Interleukin-18 Receptor alpha Subunit
"Interleukin-18 Receptor alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subunit of the interleukin-18 receptor that is responsible of extracellular binding of IL-18.
Descriptor ID |
D053727
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MeSH Number(s) |
D12.776.543.750.705.852.420.830.500
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Concept/Terms |
Interleukin-18 Receptor alpha Subunit- Interleukin-18 Receptor alpha Subunit
- Interleukin 18 Receptor alpha Subunit
- Antigens, CDw218a
- Interleukin-18 Receptor alpha Chain
- Interleukin 18 Receptor alpha Chain
- Interleukin 18 Receptor 1
- IL1 Receptor-Related Protein
- IL1 Receptor Related Protein
- CDw218a Antigen
- Antigen, CDw218a
- CDw218a Antigens
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Below are MeSH descriptors whose meaning is more general than "Interleukin-18 Receptor alpha Subunit".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-18 Receptor alpha Subunit".
This graph shows the total number of publications written about "Interleukin-18 Receptor alpha Subunit" by people in this website by year, and whether "Interleukin-18 Receptor alpha Subunit" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 | 2000 | 0 | 1 | 1 | 2001 | 0 | 3 | 3 | 2003 | 0 | 2 | 2 | 2006 | 0 | 1 | 1 | 2009 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2015 | 1 | 0 | 1 | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-18 Receptor alpha Subunit" by people in Profiles.
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Cavalli G, Koenders M, Kalabokis V, Kim J, Tan AC, Garlanda C, Mantovani A, Dagna L, Joosten LA, Dinarello CA. Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation. Rheumatology (Oxford). 2016 Dec; 55(12):2220-2229.
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Nold-Petry CA, Lo CY, Rudloff I, Elgass KD, Li S, Gantier MP, Lotz-Havla AS, Gersting SW, Cho SX, Lao JC, Ellisdon AM, Rotter B, Azam T, Mangan NE, Rossello FJ, Whisstock JC, Bufler P, Garlanda C, Mantovani A, Dinarello CA, Nold MF. IL-37 requires the receptors IL-18Ra and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction. Nat Immunol. 2015 Apr; 16(4):354-65.
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Dinarello CA, Bufler P. Interleukin-37. Semin Immunol. 2013 Dec 15; 25(6):466-8.
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Nold-Petry CA, Nold MF, Nielsen JW, Bustamante A, Zepp JA, Storm KA, Hong JW, Kim SH, Dinarello CA. Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling. J Biol Chem. 2009 Sep 18; 284(38):25900-11.
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Netea MG, Joosten LA, Lewis E, Jensen DR, Voshol PJ, Kullberg BJ, Tack CJ, van Krieken H, Kim SH, Stalenhoef AF, van de Loo FA, Verschueren I, Pulawa L, Akira S, Eckel RH, Dinarello CA, van den Berg W, van der Meer JW. Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance. Nat Med. 2006 Jun; 12(6):650-6.
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Azam T, Novick D, Bufler P, Yoon DY, Rubinstein M, Dinarello CA, Kim SH. Identification of a critical Ig-like domain in IL-18 receptor alpha and characterization of a functional IL-18 receptor complex. J Immunol. 2003 Dec 15; 171(12):6574-80.
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Dinarello CA, Novick D, Rubinstein M, Lonnemann G. Interleukin 18 and interleukin 18 binding protein: possible role in immunosuppression of chronic renal failure. Blood Purif. 2003; 21(3):258-70.
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Lee SJ, Cho YS, Cho MC, Shim JH, Lee KA, Ko KK, Choe YK, Park SN, Hoshino T, Kim S, Dinarello CA, Yoon DY. Both E6 and E7 oncoproteins of human papillomavirus 16 inhibit IL-18-induced IFN-gamma production in human peripheral blood mononuclear and NK cells. J Immunol. 2001 Jul 01; 167(1):497-504.
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Fantuzzi G, Reed D, Qi M, Scully S, Dinarello CA, Senaldi G. Role of interferon regulatory factor-1 in the regulation of IL-18 production and activity. Eur J Immunol. 2001 Feb; 31(2):369-75.
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Kim SH, Reznikov LL, Stuyt RJ, Selzman CH, Fantuzzi G, Hoshino T, Young HA, Dinarello CA. Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain. J Immunol. 2001 Jan 01; 166(1):148-54.
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