4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
"4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia.
| Descriptor ID |
D015772
|
| MeSH Number(s) |
D03.383.129.539.120
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine".
Below are MeSH descriptors whose meaning is more specific than "4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine".
This graph shows the total number of publications written about "4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine" by people in this website by year, and whether "4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine" was a major or minor topic of these publications.
![]()
To see the data from this visualization as text,
click here.
Below are the most recent publications written about "4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine" by people in Profiles.
-
Dinarello CA, Bishai I, Rosenwasser LJ, Coceani F. The influence of lipoxygenase inhibitors on the in vitro production of human leukocytic pyrogen and lymphocyte activating factor (interleukin-1). Int J Immunopharmacol. 1984; 6(1):43-50.
-
Dinarello CA, Marnoy SO, Rosenwasser LJ. Role of arachidonate metabolism in the immunoregulatory function of human leukocytic pyrogen/lymphocyte-activating factor/interleukin 1. J Immunol. 1983 Feb; 130(2):890-5.