 Morkos Adel Ibrahim Henen
| Title | Research Instructor |
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| Institution | University of Colorado Denver - Anschutz Medical Campus |
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| Department | SOM-BioChem&Molecular Genetics |
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 Biography | Vienna University, Austria | PhD with Honor degree | | Molecular Biology, Drug Discovery | | CNRS, Lille 1 University, France | | | Drug discovery, NMR, Molecular Biology | | Health Science Center, San Antonio, TX, USA | | | Molecular Biology, Drug Discovery, Biochemistry | | University of Pitsburgh, PA, USA | | | Structural Biology, NMR, Drug Discovery | | Faculty of Pharmacy, Mansoura University, Egypt | Master | | Pharmaceutical Chemistry | | Faculty of Pharmacy, Mansoura University, Egypt | Bachelor | | Pharmacy |
| 2015 | Best Poster Award, Health Science Center, University of Texas, SA, USA | | 2016 | Bursary Award, Drug Discovery Course, Douglas Connect GmbH Bärmeggenweg 14 Zeiningen, Aargau 4314 CH | | 2013 - 2014 | Marie Curie Grant member, European Union, Brussels, Belgium | | 2009 - 2012 | Ku mit Agypten, Austrian Ministry of High Education, Vienna, Austria |
Overview Research Oct 1, 2009 Austrian Ministry of High Education, Vienna Austria
Chemistry and NMR studies of Beta Catenin
Role: PhD fellow |
| (Christian Ottmann and Isabelle Landrieu)Jan 1, 2013 - Dec 31, 2014 European Union - Marie Curie Project
14-3-3 Stabilizers
Role: Senior PostDoctoral Fellow |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Morkos A. Henen et al. Understanding Chemistry and Unique NMR Characters of Novel Amide and Ester Leflunomide Analogues. Magnetochemistry. 2017; 4(3):41.
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Nichols PJ, Born A, Henen MA, Strotz D, Orts J, Olsson S, Güntert P, Chi CN, Vögeli B. The Exact Nuclear Overhauser Enhancement: Recent Advances. Molecules. 2017 Jul 14; 22(7). PMID: 28708092.
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Villarreal MM, Kim SK, Barron L, Kodali R, Baardsnes J, Hinck CS, Krzysiak TC, Henen MA, Pakhomova O, Mendoza V, O'Connor-McCourt MD, Lafer EM, López-Casillas F, Hinck AP. Correction to Binding Properties of the Transforming Growth Factor-ß Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling. Biochemistry. 2017 07 18; 56(28):3689. PMID: 28677957.
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Hinck, Andrew
Henen, Morkos A.
Zwieb, Christian
Kodali, Ravindra
Hinck, Cynthia S. Methyl-Labeling Assisted NMR Structure Determination of a 66 KDA Growth Factor-Receptor Complex. Biophysical Journal. 2017; 112(3):487a-488a.
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Villarreal MM, Kim SK, Barron L, Kodali R, Baardsnes J, Hinck CS, Krzysiak TC, Henen MA, Pakhomova O, Mendoza V, O'Connor-McCourt MD, Lafer EM, López-Casillas F, Hinck AP. Binding Properties of the Transforming Growth Factor-ß Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling. Biochemistry. 2016 12 13; 55(49):6880-6896. PMID: 27951653.
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Byrne C, Henen MA, Belnou M, Cantrelle FX, Kamah A, Qi H, Giustiniani J, Chambraud B, Baulieu EE, Lippens G, Landrieu I, Jacquot Y. A ß-Turn Motif in the Steroid Hormone Receptor's Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52. Biochemistry. 2016 09 27; 55(38):5366-76. PMID: 27641460.
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Milroy LG, Bartel M, Henen MA, Leysen S, Adriaans JM, Brunsveld L, Landrieu I, Ottmann C. Stabilizer-Guided Inhibition of Protein-Protein Interactions. Angew Chem Int Ed Engl. 2015 Dec 21; 54(52):15720-4. PMID: 26537010.
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Geist L, Henen MA, Haiderer S, Schwarz TC, Kurzbach D, Zawadzka-Kazimierczuk A, Saxena S, Zerko S, Kozminski W, Hinderberger D, Konrat R. Protonation-dependent conformational variability of intrinsically disordered proteins. Protein Sci. 2013 Sep; 22(9):1196-205. PMID: 23821606; PMCID: PMC3776332.
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Kurzbach D, Platzer G, Schwarz TC, Henen MA, Konrat R, Hinderberger D. Cooperative unfolding of compact conformations of the intrinsically disordered protein osteopontin. Biochemistry. 2013 Aug 06; 52(31):5167-75. PMID: 23848319; PMCID: PMC3737600.
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Dennis Kurzbach, Gerald Platzer, Thomas Schwarz, Morkos Henen, Robert Konrat, Dariush Hinderberger
. Cooperatively Folded Conformational Sub-States in Intrinsically Disordered Proteins as Revealed by EPR Spectroscopy. Biophysical Journal. 2013; 104(2):P190a.
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Orbán-Németh Z, Henen MA, Geist L, Zerko S, Saxena S, Stanek J, Kozminski W, Propst F, Konrat R. Backbone and partial side chain assignment of the microtubule binding domain of the MAP1B light chain. Biomol NMR Assign. 2014 Apr; 8(1):123-7. PMID: 23339032; PMCID: PMC3955483.
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Henen MA, Coudevylle N, Geist L, Konrat R. Toward rational fragment-based lead design without 3D structures. J Med Chem. 2012 Sep 13; 55(17):7909-19. PMID: 22889313; PMCID: PMC3557921.
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Henen, Morkos A.
El Bialy, Serry A A
Goda, Fatma E.
Nasr, Magda N A
Eisa, Hassan M. [1,2,4]Triazolo[4,3-a]quinoxaline: Synthesis, antiviral, and antimicrobial activities. Medicinal Chemistry Research. 2012; 21(9):2368-2378.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 2012 | 2 | | 2013 | 4 | | 2015 | 1 | | 2016 | 2 | | 2017 | 4 |
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