Longitudinal whole genome analysis of pre and post drug treatment Mycobacterium tuberculosis isolates reveals progressive steps to drug resistance.

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Longitudinal whole genome analysis of pre and post drug treatment Mycobacterium tuberculosis isolates reveals progressive steps to drug resistance.

Datta G, Nieto LM, Davidson RM, Mehaffy C, Pederson C, Dobos KM, Strong M. Longitudinal whole genome analysis of pre and post drug treatment Mycobacterium tuberculosis isolates reveals progressive steps to drug resistance. Tuberculosis (Edinb). 2016 05; 98:50-5.

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subject areas

Antitubercular Agents
Bacterial Proteins
Bacterial Toxins
Catalase
DNA Mutational Analysis
Drug Resistance, Multiple, Bacterial
Genome, Bacterial
Genotype
Humans
Isoniazid
Microbial Sensitivity Tests
Models, Molecular
Mutation
Mycobacterium tuberculosis
Phenotype
Polymorphism, Single Nucleotide
Protein Conformation
Rifampin
Structure-Activity Relationship
Time Factors
Treatment Outcome
Tuberculosis

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Michael Strong

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