OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis.

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OLT1177 (Dapansutrile)

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OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis.

Sánchez-Fernández A, Skouras DB, Dinarello CA, López-Vales R. OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis. Front Immunol. 2019; 10:2578.

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subject areas

Administration, Oral
Animals
Anti-Inflammatory Agents
CD4-Positive T-Lymphocytes
Cognitive Dysfunction
Encephalomyelitis, Autoimmune, Experimental
Female
Inflammasomes
Macrophages
Mice, Inbred C57BL
Nitriles
NLR Family, Pyrin Domain-Containing 3 Protein
Spinal Cord

authors with profiles

Charles A Dinarello

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