 H-Y Antigen
"H-Y Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sex-specific cell surface antigen produced by the sex-determining gene of the Y chromosome in mammals. It causes syngeneic grafts from males to females to be rejected and interacts with somatic elements of the embryologic undifferentiated gonad to produce testicular organogenesis.
| Descriptor ID |
D006182
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| MeSH Number(s) |
D23.050.301.500.600.400 D23.050.705.552.600.400
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| Concept/Terms |
H-Y Antigen- H-Y Antigen
- Antigen, H-Y
- H Y Antigen
- HY Antigen
- Antigen, HY
- GA-1 Germ Cell Antigen
- GA 1 Germ Cell Antigen
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Below are MeSH descriptors whose meaning is more general than "H-Y Antigen".
Below are MeSH descriptors whose meaning is more specific than "H-Y Antigen".
This graph shows the total number of publications written about "H-Y Antigen" by people in this website by year, and whether "H-Y Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "H-Y Antigen" by people in Profiles.
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Shand JC, Qin H, Nasholm N, Capitini CM, Fry TJ. Minor antigen distribution predicts site-specific graft-versus-tumor activity of adoptively transferred, minor antigen-specific CD8 T Cells. Biol Blood Marrow Transplant. 2014 Jan; 20(1):26-36.
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Capitini CM, Nasholm NM, Duncan BB, Guimond M, Fry TJ. Graft-versus-host disease impairs vaccine responses through decreased CD4+ and CD8+ T cell proliferation and increased perforin-mediated CD8+ T cell apoptosis. J Immunol. 2013 Feb 01; 190(3):1351-9.
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Marshall HD, Prince AL, Berg LJ, Welsh RM. IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions. J Immunol. 2010 Aug 01; 185(3):1419-28.
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Fry TJ, Shand JL, Milliron M, Tasian SK, Mackall CL. Antigen loading of DCs with irradiated apoptotic tumor cells induces improved anti-tumor immunity compared to other approaches. Cancer Immunol Immunother. 2009 Aug; 58(8):1257-64.
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Manders PM, Hunter PJ, Telaranta AI, Carr JM, Marshall JL, Carrasco M, Murakami Y, Palmowski MJ, Cerundolo V, Kaech SM, Ahmed R, Fearon DT. BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes. Proc Natl Acad Sci U S A. 2005 May 24; 102(21):7418-25.
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Melchionda F, Fry TJ, Milliron MJ, McKirdy MA, Tagaya Y, Mackall CL. Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool. J Clin Invest. 2005 May; 115(5):1177-87.
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Melchionda F, McKirdy MK, Medeiros F, Fry TJ, Mackall CL. Escape from immune surveillance does not result in tolerance to tumor-associated antigens. J Immunother. 2004 Sep-Oct; 27(5):329-38.
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Wang J, Fu YX. LIGHT (a cellular ligand for herpes virus entry mediator and lymphotoxin receptor)-mediated thymocyte deletion is dependent on the interaction between TCR and MHC/self-peptide. J Immunol. 2003 Apr 15; 170(8):3986-93.
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Kawauchi M, Gundry SR, de Begona JA, Fullerton DA, Razzouk AJ, Boucek MM, Nehlsen-Cannarella S, Bailey LL. Male donor into female recipient increases the risk of pediatric heart allograft rejection. Ann Thorac Surg. 1993 Mar; 55(3):716-8.
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Carlon N. [Role of HY antigen in human and mammalian gonadal organogenesis (author's transl)]. Pathol Biol (Paris). 1982 Jan; 30(1):49-60.
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