Hepatic Encephalopathy
"Hepatic Encephalopathy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
Descriptor ID |
D006501
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MeSH Number(s) |
C06.552.308.500.356 C10.228.140.163.360 C18.452.132.360
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Concept/Terms |
Hepatic Encephalopathy- Hepatic Encephalopathy
- Encephalopathies, Hepatic
- Hepatic Encephalopathies
- Encephalopathy, Hepatic
- Portal-Systemic Encephalopathy
- Portal Systemic Encephalopathy
- Encephalopathy, Portal-Systemic
- Encephalopathies, Portal-Systemic
- Encephalopathy, Portal Systemic
- Portal-Systemic Encephalopathies
- Encephalopathy, Portosystemic
- Hepatocerebral Encephalopathy
- Portosystemic Encephalopathy
- Encephalopathies, Portosystemic
- Portosystemic Encephalopathies
- Encephalopathy, Hepatocerebral
- Encephalopathies, Hepatocerebral
- Hepatocerebral Encephalopathies
Hepatic Coma- Hepatic Coma
- Coma, Hepatic
- Comas, Hepatic
- Hepatic Comas
Hepatic Stupor- Hepatic Stupor
- Hepatic Stupors
- Stupor, Hepatic
- Stupors, Hepatic
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Below are MeSH descriptors whose meaning is more general than "Hepatic Encephalopathy".
Below are MeSH descriptors whose meaning is more specific than "Hepatic Encephalopathy".
This graph shows the total number of publications written about "Hepatic Encephalopathy" by people in this website by year, and whether "Hepatic Encephalopathy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 | 1997 | 1 | 0 | 1 | 1998 | 2 | 0 | 2 | 1999 | 0 | 1 | 1 | 2007 | 1 | 0 | 1 | 2009 | 1 | 0 | 1 | 2011 | 0 | 2 | 2 | 2012 | 0 | 1 | 1 | 2013 | 1 | 1 | 2 | 2014 | 1 | 0 | 1 | 2015 | 1 | 1 | 2 | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hepatic Encephalopathy" by people in Profiles.
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Bajaj JS, Shamsaddini A, Fagan A, McGeorge S, Gavis E, Sikaroodi M, Brenner LA, Wade JB, Gillevet PM. Distinct gut microbial compositional and functional changes associated with impaired inhibitory control in patients with cirrhosis. Gut Microbes. 2021 Jan-Dec; 13(1):1953247.
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Press CA, Morgan L, Mills M, Stack CV, Goldstein JL, Alonso EM, Wainwright MS. Spectral Electroencephalogram Analysis for the Evaluation of Encephalopathy Grade in Children With Acute Liver Failure. Pediatr Crit Care Med. 2017 01; 18(1):64-72.
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Nadim MK, Durand F, Kellum JA, Levitsky J, O'Leary JG, Karvellas CJ, Bajaj JS, Davenport A, Jalan R, Angeli P, Caldwell SH, Fern?ndez J, Francoz C, Garcia-Tsao G, Gin?s P, Ison MG, Kramer DJ, Mehta RL, Moreau R, Mulligan D, Olson JC, Pomfret EA, Senzolo M, Steadman RH, Subramanian RM, Vincent JL, Genyk YS. Management of the critically ill patient with cirrhosis: A multidisciplinary perspective. J Hepatol. 2016 Mar; 64(3):717-35.
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McMillin M, Frampton G, Tobin R, Dusio G, Smith J, Shin H, Newell-Rogers K, Grant S, DeMorrow S. TGR5 signaling reduces neuroinflammation during hepatic encephalopathy. J Neurochem. 2015 Nov; 135(3):565-76.
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Casadaban LC, Parvinian A, Minocha J, Lakhoo J, Grant CW, Ray CE, Knuttinen MG, Bui JT, Gaba RC. Clearing the Confusion over Hepatic Encephalopathy After TIPS Creation: Incidence, Prognostic Factors, and Clinical Outcomes. Dig Dis Sci. 2015 Apr; 60(4):1059-66.
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Mokhtarani M, Diaz GA, Rhead W, Berry SA, Lichter-Konecki U, Feigenbaum A, Schulze A, Longo N, Bartley J, Berquist W, Gallagher R, Smith W, McCandless SE, Harding C, Rockey DC, Vierling JM, Mantry P, Ghabril M, Brown RS, Dickinson K, Moors T, Norris C, Coakley D, Milikien DA, Nagamani SC, Lemons C, Lee B, Scharschmidt BF. Elevated phenylacetic acid levels do not correlate with adverse events in patients with urea cycle disorders or hepatic encephalopathy and can be predicted based on the plasma PAA to PAGN ratio. Mol Genet Metab. 2013 Dec; 110(4):446-53.
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Squires RH, Dhawan A, Alonso E, Narkewicz MR, Shneider BL, Rodriguez-Baez N, Olio DD, Karpen S, Bucuvalas J, Lobritto S, Rand E, Rosenthal P, Horslen S, Ng V, Subbarao G, Kerkar N, Rudnick D, Lopez MJ, Schwarz K, Romero R, Elisofon S, Doo E, Robuck PR, Lawlor S, Belle SH. Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: a placebo-controlled clinical trial. Hepatology. 2013 Apr; 57(4):1542-9.
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El Ansary M, Mogawer S, Elhamid SA, Alwakil S, Aboelkasem F, Sabaawy HE, Abdelhalim O. Immunotherapy by autologous dendritic cell vaccine in patients with advanced HCC. J Cancer Res Clin Oncol. 2013 Jan; 139(1):39-48.
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Sundaram SS, Alonso EM, Narkewicz MR, Zhang S, Squires RH. Characterization and outcomes of young infants with acute liver failure. J Pediatr. 2011 Nov; 159(5):813-818.e1.
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Wang GS, Monte A, Bagdure D, Heard K. Hepatic failure despite early acetylcysteine following large acetaminophen-diphenhydramine overdose. Pediatrics. 2011 Apr; 127(4):e1077-80.
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