 Muromonab-CD3
"Muromonab-CD3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell depletion and modulation of the T-cell receptor complex (CD3/Ti).
| Descriptor ID |
D016853
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| MeSH Number(s) |
D12.776.124.486.485.114.224.075.570 D12.776.124.486.485.114.619.393.570 D12.776.124.790.651.114.224.075.570 D12.776.124.790.651.114.619.393.570 D12.776.377.715.548.114.224.284.570 D12.776.377.715.548.114.619.393.570
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| Concept/Terms |
Muromonab-CD3- Muromonab-CD3
- Muromonab CD3
- OKT3
- Monoclonal Antibody OKT3
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Below are MeSH descriptors whose meaning is more general than "Muromonab-CD3".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Blood Proteins [D12.776.124]
- Immunoproteins [D12.776.124.486]
- Immunoglobulins [D12.776.124.486.485]
- Antibodies [D12.776.124.486.485.114]
- Antibodies, Monoclonal [D12.776.124.486.485.114.224]
- Antibodies, Monoclonal, Murine-Derived [D12.776.124.486.485.114.224.075]
- Muromonab-CD3 [D12.776.124.486.485.114.224.075.570]
- Immunoglobulin Isotypes [D12.776.124.486.485.114.619]
- Immunoglobulin G [D12.776.124.486.485.114.619.393]
- Muromonab-CD3 [D12.776.124.486.485.114.619.393.570]
- Serum Globulins [D12.776.124.790]
- Immunoglobulins [D12.776.124.790.651]
- Antibodies [D12.776.124.790.651.114]
- Antibodies, Monoclonal [D12.776.124.790.651.114.224]
- Antibodies, Monoclonal, Murine-Derived [D12.776.124.790.651.114.224.075]
- Muromonab-CD3 [D12.776.124.790.651.114.224.075.570]
- Immunoglobulin Isotypes [D12.776.124.790.651.114.619]
- Immunoglobulin G [D12.776.124.790.651.114.619.393]
- Muromonab-CD3 [D12.776.124.790.651.114.619.393.570]
- Globulins [D12.776.377]
- Serum Globulins [D12.776.377.715]
- Immunoglobulins [D12.776.377.715.548]
- Antibodies [D12.776.377.715.548.114]
- Antibodies, Monoclonal [D12.776.377.715.548.114.224]
- Antibodies, Monoclonal, Murine-Derived [D12.776.377.715.548.114.224.284]
- Muromonab-CD3 [D12.776.377.715.548.114.224.284.570]
- Immunoglobulin Isotypes [D12.776.377.715.548.114.619]
- Immunoglobulin G [D12.776.377.715.548.114.619.393]
- Muromonab-CD3 [D12.776.377.715.548.114.619.393.570]
Below are MeSH descriptors whose meaning is more specific than "Muromonab-CD3".
This graph shows the total number of publications written about "Muromonab-CD3" by people in this website by year, and whether "Muromonab-CD3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Muromonab-CD3" by people in Profiles.
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Kerkar N, Morotti RA, Iyer K, Arnon R, Miloh T, Sturdevant M, Suchy F, Florman S, Emre S. Anti-lymphocyte therapy successfully controls late "cholestatic" rejection in pediatric liver transplant recipients. Clin Transplant. 2011 Nov-Dec; 25(6):E584-91.
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Zimmerman MA, Kelly MA, Campsen J, Mandell MS, Wachs M, Bak T, Skibba A, Lancaster B, Kam I. The influence of OKT3 therapy on hepatocellular carcinoma recurrence following liver transplantation. Clin Transplant. 2010 Jul-Aug; 24(4):E103-8.
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Herold KC, Gitelman S, Greenbaum C, Puck J, Hagopian W, Gottlieb P, Sayre P, Bianchine P, Wong E, Seyfert-Margolis V, Bourcier K, Bluestone JA. Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years. Clin Immunol. 2009 Aug; 132(2):166-73.
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McOmber D, Ibrahim J, Lublin DM, Saffitz JE, Ong-Simon C, Mendeloff EN, Huddleston CB, Canter CE. Non-ischemic left ventricular dysfunction after pediatric cardiac transplantation: treatment with plasmapheresis and OKT3. J Heart Lung Transplant. 2004 May; 23(5):552-7.
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Dunkelberg JC, Trotter JF, Wachs M, Bak T, Kugelmas M, Steinberg T, Everson GT, Kam I. Sirolimus as primary immunosuppression in liver transplantation is not associated with hepatic artery or wound complications. Liver Transpl. 2003 May; 9(5):463-8.
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Sollinger HW, Odorico JS, Knechtle SJ, D'Alessandro AM, Kalayoglu M, Pirsch JD. Experience with 500 simultaneous pancreas-kidney transplants. Ann Surg. 1998 Sep; 228(3):284-96.
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Stegall MD, Simon M, Wachs ME, Chan L, Nolan C, Kam I. Mycophenolate mofetil decreases rejection in simultaneous pancreas-kidney transplantation when combined with tacrolimus or cyclosporine. Transplantation. 1997 Dec 27; 64(12):1695-700.
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Conti DJ, Shen G, Singh T, Isenberg A, Freed BM. Ganciclovir prophylaxis of cytomegalovirus disease. Transplant Proc. 1997 Feb-Mar; 29(1-2):804-6.
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Gallichio MH, Conti DJ, Lempert N, Gruber SA, Geiselhart L, Freed BM. Calcium-mediated induction of anergy in the Jurkat T-cell line. Transplant Proc. 1994 Dec; 26(6):3458-9.
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Taylor DO, Bristow MR, O'Connell JB, Ensley RD, Olsen SL, Hammond EH, Wagoner LE, Renlund DG. A prospective, randomized comparison of cyclophosphamide and azathioprine for early rejection prophylaxis after cardiac transplantation. Decreased sensitization to OKT3. Transplantation. 1994 Sep 27; 58(6):645-9.
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