 Pulmonary Surfactant-Associated Protein A
"Pulmonary Surfactant-Associated Protein A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.
| Descriptor ID |
D037662
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| MeSH Number(s) |
D12.776.503.280.249.600 D12.776.823.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pulmonary Surfactant-Associated Protein A".
Below are MeSH descriptors whose meaning is more specific than "Pulmonary Surfactant-Associated Protein A".
This graph shows the total number of publications written about "Pulmonary Surfactant-Associated Protein A" by people in this website by year, and whether "Pulmonary Surfactant-Associated Protein A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2000 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 2 | 1 | 3 | | 2006 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 1 | 2 | | 2010 | 1 | 1 | 2 | | 2011 | 2 | 0 | 2 | | 2012 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2019 | 0 | 2 | 2 | | 2020 | 1 | 0 | 1 | | 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Pulmonary Surfactant-Associated Protein A" by people in Profiles.
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Tanyaratsrisakul S, Bochkov YA, White V, Lee H, Loeffler J, Everman J, Schiltz AM, Freeman KL, Hamlington KL, Secor EA, Jackson ND, Chu HW, Liu AH, Ledford JG, Kraft M, Seibold MA, Voelker DR, Numata M. Surfactant Protein A Inhibits Human Rhinovirus C Binding and Infection of Airway Epithelial Cells from Pediatric Asthma. Viruses. 2024 10 30; 16(11).
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Schaunaman N, Cervantes D, Nichols T, Numata M, Ledford JG, Kraft M, Chu HW. Cooperation of immune regulators Tollip and surfactant protein A inhibits influenza A virus infection in mice. Respir Res. 2024 May 03; 25(1):193.
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Younis US, Chu HW, Kraft M, Ledford JG. A 20-Mer Peptide Derived from the Lectin Domain of SP-A2 Decreases Tumor Necrosis Factor Alpha Production during Mycoplasma pneumoniae Infection. Infect Immun. 2020 08 19; 88(9).
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Francisco D, Wang Y, Conway M, Hurbon AN, Dy ABC, Addison KJ, Chu HW, Voelker DR, Ledford JG, Kraft M. Surfactant Protein-A Protects against IL-13-Induced Inflammation in Asthma. J Immunol. 2020 05 15; 204(10):2829-2839.
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Sanchez TR, Oelsner EC, Lederer DJ, Lo Cascio CM, Jones MR, Grau-Perez M, Francesconi KA, Goessler W, Perzanowski MS, Barr RG, Navas-Acien A. Rice Consumption and Subclinical Lung Disease in US Adults: Observational Evidence From the Multi-Ethnic Study of Atherosclerosis. Am J Epidemiol. 2019 09 01; 188(9):1655-1665.
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Moore C, Blumhagen RZ, Yang IV, Walts A, Powers J, Walker T, Bishop M, Russell P, Vestal B, Cardwell J, Markin CR, Mathai SK, Schwarz MI, Steele MP, Lee J, Brown KK, Loyd JE, Crapo JD, Silverman EK, Cho MH, James JA, Guthridge JM, Cogan JD, Kropski JA, Swigris JJ, Bair C, Kim DS, Ji W, Kim H, Song JW, Maier LA, Pacheco KA, Hirani N, Poon AS, Li F, Jenkins RG, Braybrooke R, Saini G, Maher TM, Molyneaux PL, Saunders P, Zhang Y, Gibson KF, Kass DJ, Rojas M, Sembrat J, Wolters PJ, Collard HR, Sundy JS, O'Riordan T, Strek ME, Noth I, Ma SF, Porteous MK, Kreider ME, Patel NB, Inoue Y, Hirose M, Arai T, Akagawa S, Eickelberg O, Fernandez IE, Behr J, Mogulkoc N, Corte TJ, Glaspole I, Tomassetti S, Ravaglia C, Poletti V, Crestani B, Borie R, Kannengiesser C, Parfrey H, Fiddler C, Rassl D, Molina-Molina M, Machahua C, Worboys AM, Gudmundsson G, Isaksson HJ, Lederer DJ, Podolanczuk AJ, Montesi SB, Bendstrup E, Danchel V, Selman M, Pardo A, Henry MT, Keane MP, Doran P, Va??kov? M, Sterclova M, Ryerson CJ, Wilcox PG, Okamoto T, Furusawa H, Miyazaki Y, Laurent G, Baltic S, Prele C, Moodley Y, Shea BS, Ohta K, Suzukawa M, Narumoto O, Nathan SD, Venuto DC, Woldehanna ML, Kokturk N, de Andrade JA, Luckhardt T, Kulkarni T, Bonella F, Donnelly SC, McElroy A, Armstong ME, Aranda A, Carbone RG, Puppo F, Beckman KB, Nickerson DA, Fingerlin TE, Schwartz DA. Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 07 15; 200(2):199-208.
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Kim JS, Podolanczuk AJ, Borker P, Kawut SM, Raghu G, Kaufman JD, Stukovsky KDH, Hoffman EA, Barr RG, Gottlieb DJ, Redline SS, Lederer DJ. Obstructive Sleep Apnea and Subclinical Interstitial Lung Disease in the Multi-Ethnic Study of Atherosclerosis (MESA). Ann Am Thorac Soc. 2017 Dec; 14(12):1786-1795.
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Ledford JG, Voelker DR, Addison KJ, Wang Y, Nikam VS, Degan S, Kandasamy P, Tanyaratsrisakul S, Fischer BM, Kraft M, Hollingsworth JW. Genetic variation in SP-A2 leads to differential binding to Mycoplasma pneumoniae membranes and regulation of host responses. J Immunol. 2015 Jun 15; 194(12):6123-32.
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Foster MW, Thompson JW, Ledford JG, Dubois LG, Hollingsworth JW, Francisco D, Tanyaratsrisakul S, Voelker DR, Kraft M, Moseley MA, Foster WM. Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A. J Proteome Res. 2014 Aug 01; 13(8):3722-32.
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Steele MP, Schwartz DA. Molecular mechanisms in progressive idiopathic pulmonary fibrosis. Annu Rev Med. 2013; 64:265-76.
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