 Pulmonary Surfactant-Associated Protein D
"Pulmonary Surfactant-Associated Protein D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens and enhances their opsinization and killing by phagocytic cells. Surfactant protein D contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.
| Descriptor ID |
D037663
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| MeSH Number(s) |
D12.776.503.280.249.625 D12.776.823.249
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| Concept/Terms |
Pulmonary Surfactant-Associated Protein D- Pulmonary Surfactant-Associated Protein D
- Pulmonary Surfactant Associated Protein D
- Lung Protein D
- Surfactant-Associated Glycoprotein D
- Surfactant Associated Glycoprotein D
- Surfactant Protein D
- SP-D
- Pulmonary Surfactant Protein D
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Below are MeSH descriptors whose meaning is more general than "Pulmonary Surfactant-Associated Protein D".
Below are MeSH descriptors whose meaning is more specific than "Pulmonary Surfactant-Associated Protein D".
This graph shows the total number of publications written about "Pulmonary Surfactant-Associated Protein D" by people in this website by year, and whether "Pulmonary Surfactant-Associated Protein D" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2002 | 1 | 2 | 3 | | 2003 | 1 | 1 | 2 | | 2006 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 2 | 0 | 2 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pulmonary Surfactant-Associated Protein D" by people in Profiles.
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Rose JA, Steele MP, Kosak Lopez EJ, Axelsson GT, Galecio Chao AG, Waich A, Regan K, Gulati S, Maeda AH, Sultana S, Cutting C, Tukpah AC, Synn AJ, Rice MB, Goldberg HJ, Lee JS, Lynch DA, Putman RK, Hatabu H, Raby BA, Schwartz DA, Rosas IO, Hunninghake GM. Protein biomarkers of interstitial lung abnormalities in relatives of patients with pulmonary fibrosis. Eur Respir J. 2025 Jun; 65(6).
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Gottlieb DJ, Lederer DJ, Kim JS, Tracy RP, Gao S, Redline S, Jelic S. Effect of positive airway pressure therapy of obstructive sleep apnea on circulating Angiopoietin-2. Sleep Med. 2022 08; 96:119-121.
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Allawzi A, Nozik-Grayck E. S-nitrosylation of surfactant protein-D: a proinflammatory posttranslational modification. Am J Physiol Lung Cell Mol Physiol. 2019 11 01; 317(5):L537-L538.
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Svedberg FR, Brown SL, Krauss MZ, Campbell L, Sharpe C, Clausen M, Howell GJ, Clark H, Madsen J, Evans CM, Sutherland TE, Ivens AC, Thornton DJ, Grencis RK, Hussell T, Cunoosamy DM, Cook PC, MacDonald AS. The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation. Nat Immunol. 2019 05; 20(5):571-580.
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Sottile PD, Albers D, Moss MM. Neuromuscular blockade is associated with the attenuation of biomarkers of epithelial and endothelial injury in patients with moderate-to-severe acute respiratory distress syndrome. Crit Care. 2018 Mar 10; 22(1):63.
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Obeidat M, Li X, Burgess S, Zhou G, Fishbane N, Hansel NN, Boss? Y, Joubert P, Hao K, Nickle DC, van den Berge M, Timens W, Cho MH, Hobbs BD, de Jong K, Boezen M, Hung RJ, Rafaels N, Mathias R, Ruczinski I, Beaty TH, Barnes KC, Par? PD, Sin DD. Surfactant protein D is a causal risk factor for COPD: results of Mendelian randomisation. Eur Respir J. 2017 11; 50(5).
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Moazed F, Burnham EL, Vandivier RW, O'Kane CM, Shyamsundar M, Hamid U, Abbott J, Thickett DR, Matthay MA, McAuley DF, Calfee CS. Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation. Thorax. 2016 12; 71(12):1130-1136.
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Bratcher PE, Gaggar A. Factors influencing the measurement of plasma/serum surfactant protein D levels by ELISA. PLoS One. 2014; 9(11):e111466.
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Bratcher PE, Gaggar A. Characterization and prevention of the adsorption of surfactant protein D to polypropylene. PLoS One. 2013; 8(9):e73467.
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Casaburi R, Celli B, Crapo J, Criner G, Croxton T, Gaw A, Jones P, Kline-Leidy N, Lomas DA, Merrill D, Polkey M, Rennard S, Sciurba F, Tal-Singer R, Stockley R, Turino G, Vestbo J, Walsh J. The COPD Biomarker Qualification Consortium (CBQC). COPD. 2013 Jun; 10(3):367-77.
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