 Receptors, Leukocyte-Adhesion
"Receptors, Leukocyte-Adhesion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of proteins associated with the capacity of LEUKOCYTES to adhere to each other and to certain substrata, e.g., the C3bi component of complement. Members of this family are the LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; (LFA-1), the MACROPHAGE-1 ANTIGEN; (Mac-1), and the INTEGRIN ALPHAXBETA2 or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited LEUKOCYTE-ADHESION DEFICIENCY SYNDROME, which is characterized by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells.
| Descriptor ID |
D016028
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| MeSH Number(s) |
D12.776.543.750.705.408.600
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| Concept/Terms |
Receptors, Leukocyte-Adhesion- Receptors, Leukocyte-Adhesion
- Receptors, Leukocyte Adhesion
- Leukocyte-Adhesion Receptor
- Leukocyte Adhesion Receptor
- Receptor, Leukocyte-Adhesion
- Leukocyte-Adhesion Receptor Family
- Leukocyte Adhesion Receptor Family
- Leu-CAM Receptor Family
- Family, Leu-CAM Receptor
- Leu CAM Receptor Family
- Receptor Family, Leu-CAM
- Leukocyte-Adhesion Receptors
- Leukocyte Adhesion Receptors
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Below are MeSH descriptors whose meaning is more general than "Receptors, Leukocyte-Adhesion".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Leukocyte-Adhesion".
This graph shows the total number of publications written about "Receptors, Leukocyte-Adhesion" by people in this website by year, and whether "Receptors, Leukocyte-Adhesion" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Leukocyte-Adhesion" by people in Profiles.
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Hellewell PG, Young SK, Henson PM, Worthen GS. Disparate role of the beta 2-integrin CD18 in the local accumulation of neutrophils in pulmonary and cutaneous inflammation in the rabbit. Am J Respir Cell Mol Biol. 1994 Apr; 10(4):391-8.
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Young SK, Worthen GS, Haslett C, Tonnesen MG, Henson PM. Interaction between chemoattractants and bacterial lipopolysaccharide in the induction and enhancement of neutrophil adhesion. Am J Respir Cell Mol Biol. 1990 Jun; 2(6):523-32.
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Salyer JL, Bohnsack JF, Knape WA, Shigeoka AO, Ashwood ER, Hill HR. Mechanisms of tumor necrosis factor-alpha alteration of PMN adhesion and migration. Am J Pathol. 1990 Apr; 136(4):831-41.
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Golde WT, McDuffie M, Kappler J, Marrack P. Identification of a new cell surface glycoprotein with accessory function in murine T cell responses. J Immunol. 1990 Feb 01; 144(3):804-10.
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