Poloxamer
"Poloxamer" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
Descriptor ID |
D020442
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MeSH Number(s) |
D02.033.455.250.700.682 D05.750.741.667 D25.720.741.667 J01.637.051.720.741.667
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Poloxamer".
Below are MeSH descriptors whose meaning is more specific than "Poloxamer".
This graph shows the total number of publications written about "Poloxamer" by people in this website by year, and whether "Poloxamer" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 2 | 0 | 2 | 2009 | 2 | 0 | 2 | 2011 | 0 | 1 | 1 | 2015 | 1 | 0 | 1 | 2016 | 1 | 1 | 2 | 2020 | 1 | 0 | 1 | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Poloxamer" by people in Profiles.
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Casella JF, Barton BA, Kanter J, Black LV, Majumdar S, Inati A, Wali Y, Drachtman RA, Abboud MR, Kilinc Y, Fuh BR, Al-Khabori MK, Takemoto CM, Salman E, Sarnaik SA, Shah N, Morris CR, Keates-Baleeiro J, Raj A, Alvarez OA, Hsu LL, Thompson AA, Sisler IY, Pace BS, Noronha SA, Lasky JL, de Julian EC, Godder K, Thornburg CD, Kamberos NL, Nuss R, Marsh AM, Owen WC, Schaefer A, Tebbi CK, Chantrain CF, Cohen DE, Karakas Z, Piccone CM, George A, Fixler JM, Singleton TC, Moulton T, Quinn CT, de Castro Lobo CL, Almomen AM, Goyal-Khemka M, Maes P, Emanuele M, Gorney RT, Padgett CS, Parsley E, Kronsberg SS, Kato GJ, Gladwin MT. Effect of Poloxamer 188 vs Placebo on Painful Vaso-Occlusive Episodes in Children and Adults With Sickle Cell Disease: A Randomized Clinical Trial. JAMA. 2021 04 20; 325(15):1513-1523.
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Westbrook LM, Henn PA, Cornish TC. Lifting Agent Granuloma: Histologic Findings Following Use of ORISE Gel for Endoscopic Resections in the Gastrointestinal Tract Am J Clin Pathol. 2020 04 15; 153(5):630-638.
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Yildirim A, Chattaraj R, Blum NT, Goldscheitter GM, Goodwin AP. Stable Encapsulation of Air in Mesoporous Silica Nanoparticles: Fluorocarbon-Free Nanoscale Ultrasound Contrast Agents. Adv Healthc Mater. 2016 06; 5(11):1290-8.
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Hotta R, Cheng L, Graham HK, Nagy N, Belkind-Gerson J, Mattheolabakis G, Amiji MM, Goldstein AM. Delivery of enteric neural progenitors with 5-HT4 agonist-loaded nanoparticles and thermosensitive hydrogel enhances cell proliferation and differentiation following transplantation in?vivo. Biomaterials. 2016 May; 88:1-11.
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?ordevic SM, Cekic ND, Savic MM, Isailovic TM, Randelovic DV, Markovic BD, Savic SR, Timic Stamenic T, Daniels R, Savic SD. Parenteral nanoemulsions as promising carriers for brain delivery of risperidone: Design, characterization and in vivo pharmacokinetic evaluation. Int J Pharm. 2015 Sep 30; 493(1-2):40-54.
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Coatney GA, Abraham AC, Fischenich KM, Button KD, Haut RC, Haut Donahue TL. Efficacy of P188 on lapine meniscus preservation following blunt trauma. J Mech Behav Biomed Mater. 2015 Jul; 47:57-64.
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Gl?wka E, Wosicka-Frackowiak H, Hyla K, Stefanowska J, Jastrzebska K, Klapiszewski L, Jesionowski T, Cal K. Polymeric nanoparticles-embedded organogel for roxithromycin delivery to hair follicles. Eur J Pharm Biopharm. 2014 Sep; 88(1):75-84.
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Pomposelli JJ, Akoad M, Flacke S, Benn JJ, Solano M, Kalra A, Madras PN. Feasibility of bloodless liver resection using Lumagel, a reverse thermoplastic polymer, to produce temporary, targeted hepatic blood flow interruption. HPB (Oxford). 2012 Feb; 14(2):115-21.
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Maurin M, St?phan O, Vial JC, Marder SR, van der Sanden B. Deep in vivo two-photon imaging of blood vessels with a new dye encapsulated in pluronic nanomicelles. J Biomed Opt. 2011 Mar; 16(3):036001.
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Maurin M, Vurth L, Vial JC, Baldeck P, Marder SR, Van der Sanden B, Stephan O. Fluorescent Pluronic nanodots for in vivo two-photon imaging. Nanotechnology. 2009 Jun 10; 20(23):235102.
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