 Certolizumab Pegol
"Certolizumab Pegol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
| Descriptor ID |
D000068582
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| MeSH Number(s) |
D05.750.741.125 D12.644.541.500.650.250 D12.776.124.486.485.114.224.060.500 D12.776.124.486.485.680.650.250 D12.776.124.790.651.114.224.060.500 D12.776.124.790.651.680.650.250 D12.776.377.715.548.114.224.200.500 D12.776.377.715.548.680.650.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Certolizumab Pegol".
- Chemicals and Drugs [D]
- Macromolecular Substances [D05]
- Polymers [D05.750]
- Polyethylene Glycols [D05.750.741]
- Certolizumab Pegol [D05.750.741.125]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Peptide Fragments [D12.644.541]
- Immunoglobulin Fragments [D12.644.541.500]
- Immunoglobulin Fab Fragments [D12.644.541.500.650]
- Certolizumab Pegol [D12.644.541.500.650.250]
- Proteins [D12.776]
- Blood Proteins [D12.776.124]
- Immunoproteins [D12.776.124.486]
- Immunoglobulins [D12.776.124.486.485]
- Antibodies [D12.776.124.486.485.114]
- Antibodies, Monoclonal [D12.776.124.486.485.114.224]
- Antibodies, Monoclonal, Humanized [D12.776.124.486.485.114.224.060]
- Certolizumab Pegol [D12.776.124.486.485.114.224.060.500]
- Immunoglobulin Fragments [D12.776.124.486.485.680]
- Immunoglobulin Fab Fragments [D12.776.124.486.485.680.650]
- Certolizumab Pegol [D12.776.124.486.485.680.650.250]
- Serum Globulins [D12.776.124.790]
- Immunoglobulins [D12.776.124.790.651]
- Antibodies [D12.776.124.790.651.114]
- Antibodies, Monoclonal [D12.776.124.790.651.114.224]
- Antibodies, Monoclonal, Humanized [D12.776.124.790.651.114.224.060]
- Certolizumab Pegol [D12.776.124.790.651.114.224.060.500]
- Immunoglobulin Fragments [D12.776.124.790.651.680]
- Immunoglobulin Fab Fragments [D12.776.124.790.651.680.650]
- Certolizumab Pegol [D12.776.124.790.651.680.650.250]
- Globulins [D12.776.377]
- Serum Globulins [D12.776.377.715]
- Immunoglobulins [D12.776.377.715.548]
- Antibodies [D12.776.377.715.548.114]
- Antibodies, Monoclonal [D12.776.377.715.548.114.224]
- Antibodies, Monoclonal, Humanized [D12.776.377.715.548.114.224.200]
- Certolizumab Pegol [D12.776.377.715.548.114.224.200.500]
- Immunoglobulin Fragments [D12.776.377.715.548.680]
- Immunoglobulin Fab Fragments [D12.776.377.715.548.680.650]
- Certolizumab Pegol [D12.776.377.715.548.680.650.250]
Below are MeSH descriptors whose meaning is more specific than "Certolizumab Pegol".
This graph shows the total number of publications written about "Certolizumab Pegol" by people in this website by year, and whether "Certolizumab Pegol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Certolizumab Pegol" by people in Profiles.
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Sieberts SK, Zhu F, Garc?a-Garc?a J, Stahl E, Pratap A, Pandey G, Pappas D, Aguilar D, Anton B, Bonet J, Eksi R, Forn?s O, Guney E, Li H, Mar?n MA, Panwar B, Planas-Iglesias J, Poglayen D, Cui J, Falcao AO, Suver C, Hoff B, Balagurusamy VSK, Dillenberger D, Neto EC, Norman T, Aittokallio T, Ammad-Ud-Din M, Azencott CA, Bell?n V, Boeva V, Bunte K, Chheda H, Cheng L, Corander J, Dumontier M, Goldenberg A, Gopalacharyulu P, Hajiloo M, Hidru D, Jaiswal A, Kaski S, Khalfaoui B, Khan SA, Kramer ER, Marttinen P, Mezlini AM, Molparia B, Pirinen M, Saarela J, Samwald M, Stoven V, Tang H, Tang J, Torkamani A, Vert JP, Wang B, Wang T, Wennerberg K, Wineinger NE, Xiao G, Xie Y, Yeung R, Zhan X, Zhao C, Greenberg J, Kremer J, Michaud K, Barton A, Coenen M, Mariette X, Miceli C, Shadick N, Weinblatt M, de Vries N, Tak PP, Gerlag D, Huizinga TWJ, Kurreeman F, Allaart CF, Louis Bridges S, Criswell L, Moreland L, Klareskog L, Saevarsdottir S, Padyukov L, Gregersen PK, Friend S, Plenge R, Stolovitzky G, Oliva B, Guan Y, Mangravite LM. Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. Nat Commun. 2016 08 23; 7:12460.
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Maruotti N, D'Onofrio F, Neve A, Santoro N, Corrado A, Cantatore FP. Anti-TNF-a and risk of infections: the experience in one center. Panminerva Med. 2014 Mar; 56(1):31-4.
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Patel AM, Moreland LW. Certolizumab pegol: a new biologic targeting rheumatoid arthritis. Expert Rev Clin Immunol. 2010 Nov; 6(6):855-66.
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