Antibodies, Heterophile
"Antibodies, Heterophile" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antibodies elicited in a different species from which the antigen originated. These antibodies are directed against a wide variety of interspecies-specific antigens, the best known of which are Forssman, Hanganutziu-Deicher (H-D), and Paul-Bunnell (P-B). Incidence of antibodies to these antigens--i.e., the phenomenon of heterophile antibody response--is useful in the serodiagnosis, pathogenesis, and prognosis of infection and latent infectious states as well as in cancer classification.
Descriptor ID |
D000910
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MeSH Number(s) |
D12.776.124.486.485.114.191 D12.776.124.790.651.114.191 D12.776.377.715.548.114.191
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Concept/Terms |
Antibodies, Heterophile- Antibodies, Heterophile
- Heterogenetic Antibodies
- Heterologous Antibodies
- Heterophile Antibodies
- Xenoantibodies
- Antibodies, Xenogenic
- Xenogenic Antibodies
- Heteroantibodies
- Antibodies, Heterologous
- Antibodies, Heterophil
- Heterophil Antibodies
- Antibodies, Heterotypic
- Heterotypic Antibodies
- Antibodies, Xenogeneic
- Xenogeneic Antibodies
- Antibodies, Heterogenetic
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Below are MeSH descriptors whose meaning is more general than "Antibodies, Heterophile".
Below are MeSH descriptors whose meaning is more specific than "Antibodies, Heterophile".
This graph shows the total number of publications written about "Antibodies, Heterophile" by people in this website by year, and whether "Antibodies, Heterophile" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 1 | 0 | 1 | 2000 | 2 | 1 | 3 | 2001 | 1 | 0 | 1 | 2004 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antibodies, Heterophile" by people in Profiles.
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Navarro Alvarez N, Zhu A, Arellano RS, Randolph MA, Duggan M, Scott Arn J, Huang CA, Sachs DH, Vagefi PA. Postnatal xenogeneic B-cell tolerance in swine following in utero intraportal antigen exposure. Xenotransplantation. 2015 Sep-Oct; 22(5):368-78.
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Liang F, Wamala I, Scalea J, Tena A, Cormack T, Pratts S, Duran-Struuck R, Elias N, Hertl M, Huang CA, Sachs DH. Increased levels of anti-non-Gal IgG following pig-to-baboon bone marrow transplantation correlate with failure of engraftment. Xenotransplantation. 2013 Nov-Dec; 20(6):458-68.
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Nagata H, Nishitai R, Shirota C, Zhang JL, Koch CA, Cai J, Awwad M, Schuurman HJ, Christians U, Abe M, Baranowska-Kortylewicz J, Platt JL, Fox IJ. Prolonged survival of porcine hepatocytes in cynomolgus monkeys. Gastroenterology. 2007 Jan; 132(1):321-9.
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Aly T, Devendra D, Barker J, Liu E, Yu L, Eisenbarth GS. Heterophile antibodies masquerade as interferon-alpha in subjects with new-onset type 1 diabetes. Diabetes Care. 2004 May; 27(5):1205-6.
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Loveland BE, Milland J, Kyriakou P, Thorley BR, Christiansen D, Lanteri MB, Regensburg M, Duffield M, French AJ, Williams L, Baker L, Brandon MR, Xing PX, Kahn D, McKenzie IF. Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons. Xenotransplantation. 2004 Mar; 11(2):171-83.
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Willman JH, Hill HR, Martins TB, Jaskowski TD, Ashwood ER, Litwin CM. Multiplex analysis of heterophil antibodies in patients with indeterminate HIV immunoassay results. Am J Clin Pathol. 2001 May; 115(5):764-9.
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Marchbank KJ, Watson CC, Ritsema DF, Holers VM. Expression of human complement receptor 2 (CR2, CD21) in Cr2-/- mice restores humoral immune function. J Immunol. 2000 Sep 01; 165(5):2354-61.
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Tsaparas YF, Brigden ML, Mathias R, Thomas E, Raboud J, Doyle PW. Proportion positive for Epstein-Barr virus, cytomegalovirus, human herpesvirus 6, Toxoplasma, and human immunodeficiency virus types 1 and 2 in heterophile-negative patients with an absolute lymphocytosis or an instrument-generated atypical lymphocyte flag. Arch Pathol Lab Med. 2000 Sep; 124(9):1324-30.
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Xu H, Gundry SR, Bailey LL. Xenoreactivity of fetal and neonatal baboon intracellular antibody against the pig. Transplant Proc. 2000 Aug; 32(5):869-71.
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Redondo MJ, Gottlieb PA, Motheral T, Mulgrew C, Rewers M, Babu S, Stephens E, Wegmann DR, Eisenbarth GS. Heterophile anti-mouse immunoglobulin antibodies may interfere with cytokine measurements in patients with HLA alleles protective for type 1A diabetes. Diabetes. 1999 Nov; 48(11):2166-70.
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