4-Butyrolactone
"4-Butyrolactone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.
Descriptor ID |
D015107
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MeSH Number(s) |
D02.540.150 D03.383.312.150
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Concept/Terms |
4-Butyrolactone- 4-Butyrolactone
- 4 Butyrolactone
- Dihydro-2(3H)-furanone
- gamma-Butyrolactone
- gamma Butyrolactone
- Furanone, tetrahydro-2-
- Furanone, tetrahydro 2
- 1,4-Butanolide
- 1,4 Butanolide
- 4-Hydroxybutyric Acid Lactone
- 4 Hydroxybutyric Acid Lactone
- Lactone, 4-Hydroxybutyric Acid
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Below are MeSH descriptors whose meaning is more general than "4-Butyrolactone".
Below are MeSH descriptors whose meaning is more specific than "4-Butyrolactone".
This graph shows the total number of publications written about "4-Butyrolactone" by people in this website by year, and whether "4-Butyrolactone" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 1 | 0 | 1 | 2004 | 0 | 1 | 1 | 2006 | 3 | 2 | 5 | 2007 | 2 | 0 | 2 | 2008 | 1 | 0 | 1 | 2009 | 0 | 1 | 1 | 2010 | 0 | 1 | 1 | 2012 | 2 | 2 | 4 | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "4-Butyrolactone" by people in Profiles.
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Miles FL, Navarro SL, Schwarz Y, Gu H, Djukovic D, Randolph TW, Shojaie A, Kratz M, Hullar MAJ, Lampe PD, Neuhouser ML, Raftery D, Lampe JW. Plasma metabolite abundances are associated with urinary enterolactone excretion in healthy participants on controlled diets. Food Funct. 2017 Sep 20; 8(9):3209-3218.
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Idrovo JP, Yang WL, Jacob A, Corbo L, Nicastro J, Coppa GF, Wang P. Inhibition of lipogenesis reduces inflammation and?organ injury in sepsis. J Surg Res. 2016 Jan; 200(1):242-9.
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DiGruccio MR, Joksimovic S, Joksovic PM, Lunardi N, Salajegheh R, Jevtovic-Todorovic V, Beenhakker MP, Goodkin HP, Todorovic SM. Hyperexcitability of rat thalamocortical networks after exposure to general anesthesia during brain development. J Neurosci. 2015 Jan 28; 35(4):1481-92.
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Li G, Wang X, Zong S, Wang J, Conti PS, Chen K. MicroPET imaging of CD13 expression using a (64)Cu-labeled dimeric NGR peptide based on sarcophagine cage. Mol Pharm. 2014 Nov 03; 11(11):3938-46.
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Zan J, Cicirelli EM, Mohamed NM, Sibhatu H, Kroll S, Choi O, Choi O, Uhlson CL, Wysoczynski CL, Wysoczinski CL, Murphy RC, Churchill ME, Hill RT, Fuqua C. A complex LuxR-LuxI type quorum sensing network in a roseobacterial marine sponge symbiont activates flagellar motility and inhibits biofilm formation. Mol Microbiol. 2012 Sep; 85(5):916-33.
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Idrovo JP, Yang WL, Nicastro J, Coppa GF, Wang P. Stimulation of carnitine palmitoyltransferase 1 improves renal function and attenuates tissue damage after ischemia/reperfusion. J Surg Res. 2012 Sep; 177(1):157-64.
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Pellinen J, Szentirmai ?. The effects of C75, an inhibitor of fatty acid synthase, on sleep and metabolism in mice. PLoS One. 2012; 7(2):e30651.
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McClean AE, Duerkop BA, Greenberg EP, Kluepfel DA. AHL signals induce rubrifacine production in a bruI mutant of Brenneria rubrifaciens. Phytopathology. 2012 Feb; 102(2):195-203.
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Chatterjee A, Drews L, Mehra S, Takano E, Kaznessis YN, Hu WS. Convergent transcription in the butyrolactone regulon in Streptomyces coelicolor confers a bistable genetic switch for antibiotic biosynthesis. PLoS One. 2011; 6(7):e21974.
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Willey JM, Gaskell AA. Morphogenetic signaling molecules of the streptomycetes. Chem Rev. 2011 Jan 12; 111(1):174-87.
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