Monensin
"Monensin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts' development of acquired immunity to the majority of coccidial species. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies.
Descriptor ID |
D008985
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MeSH Number(s) |
D03.383.312.600
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Concept/Terms |
Monensin Sodium- Monensin Sodium
- Monensin Monosodium Salt
- Monensin-A-Sodium Complex
- Monensin A Sodium Complex
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Below are MeSH descriptors whose meaning is more general than "Monensin".
Below are MeSH descriptors whose meaning is more specific than "Monensin".
This graph shows the total number of publications written about "Monensin" by people in this website by year, and whether "Monensin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Monensin" by people in Profiles.
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Chi C, Zhu H, Han M, Zhuang Y, Wu X, Xu T. Disruption of lysosome function promotes tumor growth and metastasis in Drosophila. J Biol Chem. 2010 Jul 09; 285(28):21817-23.
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Perry C, Baker OJ, Reyland ME, Grichtchenko II. PKC{alpha}{beta}{gamma}- and PKC{delta}-dependent endocytosis of NBCe1-A and NBCe1-B in salivary parotid acinar cells. Am J Physiol Cell Physiol. 2009 Dec; 297(6):C1409-23.
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Perry C, Quissell DO, Reyland ME, Grichtchenko II. Electrogenic NBCe1 (SLC4A4), but not electroneutral NBCn1 (SLC4A7), cotransporter undergoes cholinergic-stimulated endocytosis in salivary ParC5 cells. Am J Physiol Cell Physiol. 2008 Nov; 295(5):C1385-98.
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Perry C, Le H, Grichtchenko II. ANG II and calmodulin/CaMKII regulate surface expression and functional activity of NBCe1 via separate means. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F68-77.
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Fittschen C, Henson PM. Linkage of azurophil granule secretion in neutrophils to chloride ion transport and endosomal transcytosis. J Clin Invest. 1994 Jan; 93(1):247-55.
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Fittschen C, Henson PM. Selective secretion of azurophil granule contents induced by monovalent cation ionophores in human neutrophils: evidence for direct ionophore effects on the granule membrane. J Leukoc Biol. 1991 Nov; 50(5):517-28.
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McGinnes LW, Semerjian A, Morrison T. Conformational changes in Newcastle disease virus fusion glycoprotein during intracellular transport. J Virol. 1985 Nov; 56(2):341-8.
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Morrison T, Ward LJ, Semerjian A. Intracellular processing of the Newcastle disease virus fusion glycoprotein. J Virol. 1985 Mar; 53(3):851-7.
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