omega-Conotoxin GVIA
"omega-Conotoxin GVIA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurotoxic peptide, which is a cleavage product (VIa) of the omega-Conotoxin precursor protein contained in venom from the marine snail, CONUS geographus. It is an antagonist of CALCIUM CHANNELS, N-TYPE.
Descriptor ID |
D020866
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MeSH Number(s) |
D20.888.590.162.720.700 D23.946.580.590.162.720.700 D23.946.833.590.162.720.700
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Concept/Terms |
omega-Conotoxin GVIA- omega-Conotoxin GVIA
- GVIA, omega-Conotoxin
- omega Conotoxin GVIA
- omega-Conus geographus toxin
- geographus toxin, omega-Conus
- omega Conus geographus toxin
- toxin, omega-Conus geographus
- omega-CgTX
- omega CgTX
- omega-CgTX GVIA
- GVIA, omega-CgTX
- omega CgTX GVIA
- Conus geographus Toxin
- Toxin, Conus geographus
- geographus Toxin, Conus
- Conus geographus Toxin GVIA
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Below are MeSH descriptors whose meaning is more general than "omega-Conotoxin GVIA".
Below are MeSH descriptors whose meaning is more specific than "omega-Conotoxin GVIA".
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Below are the most recent publications written about "omega-Conotoxin GVIA" by people in Profiles.
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Nakashima YM, Todorovic SM, Covey DF, Lingle CJ. The anesthetic steroid (+)-3alpha-hydroxy-5alpha-androstane-17beta-carbonitrile blocks N-, Q-, and R-type, but not L- and P-type, high voltage-activated Ca2+ current in hippocampal and dorsal root ganglion neurons of the rat. Mol Pharmacol. 1998 Sep; 54(3):559-68.
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Todorovic SM, Lingle CJ. Pharmacological properties of T-type Ca2+ current in adult rat sensory neurons: effects of anticonvulsant and anesthetic agents. J Neurophysiol. 1998 Jan; 79(1):240-52.
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Mynlieff M, Beam KG. Adenosine acting at an A1 receptor decreases N-type calcium current in mouse motoneurons. J Neurosci. 1994 Jun; 14(6):3628-34.
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Skalicky JJ, Metzler WJ, Ciesla DJ, Galdes A, Pardi A. Solution structure of the calcium channel antagonist omega-conotoxin GVIA. Protein Sci. 1993 Oct; 2(10):1591-603.
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Altiere RJ, Diamond L, Thompson DC. Omega-conotoxin-sensitive calcium channels modulate autonomic neurotransmission in guinea pig airways. J Pharmacol Exp Ther. 1992 Jan; 260(1):98-103.
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Vigers AJ, Pfenninger KH. N-type and L-type calcium channels are present in nerve growth cones. Numbers increase on synaptogenesis. Brain Res Dev Brain Res. 1991 Jun 21; 60(2):197-203.
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