 Integrin beta3
"Integrin beta3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-containing and INTEGRIN ALPHAV-containing heterodimers. Integrin beta3 occurs as three alternatively spliced isoforms, designated beta3A-C.
| Descriptor ID |
D039661
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| MeSH Number(s) |
D12.776.543.750.705.408.200.750
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| Concept/Terms |
Integrin beta3- Integrin beta3
- beta3, Integrin
- CD61 Antigen
- Antigen, CD61
- GPIIIa
- beta(3) Integrin
- Platelet Glycoprotein IIIa
- Glycoprotein IIIa, Platelet
- Platelet GPIIIa
- Antigens, CD61
- CD61 Antigens
- Platelet Membrane Glycoprotein IIIa
- beta3 Integrin
- Integrin, beta3
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Below are MeSH descriptors whose meaning is more general than "Integrin beta3".
Below are MeSH descriptors whose meaning is more specific than "Integrin beta3".
This graph shows the total number of publications written about "Integrin beta3" by people in this website by year, and whether "Integrin beta3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 2 | 1 | 3 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Integrin beta3" by people in Profiles.
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Navarro-Becerra JA, Castillo JI, Di Ruzza F, Borden MA. Monodispersity Increases Adhesion Efficiency and Specificity for Ultrasound-Targeted Microbubbles. ACS Biomater Sci Eng. 2023 02 13; 9(2):991-1001.
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Botero JP, Lee K, Branchford BR, Bray PF, Freson K, Lambert MP, Luo M, Mohan S, Ross JE, Bergmeier W, Di Paola J. Glanzmann thrombasthenia: genetic basis and clinical correlates. Haematologica. 2020 04; 105(4):888-894.
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Merna N, Fung KM, Wang JJ, King CR, Hansen KC, Christman KL, George SC. Differential ?3 Integrin Expression Regulates the Response of Human Lung and Cardiac Fibroblasts to Extracellular Matrix and Its Components. Tissue Eng Part A. 2015 Aug; 21(15-16):2195-205.
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Zhu P, Davis M, Blackwelder AJ, Bachman N, Liu B, Edgerton S, Williams LL, Thor AD, Yang X. Metformin selectively targets tumor-initiating cells in ErbB2-overexpressing breast cancer models. Cancer Prev Res (Phila). 2014 Feb; 7(2):199-210.
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Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, J?r?s M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root DE, Scadden DT, Hynes RO, Mukherjee S, Stegmaier K, Jordan CT, Ebert BL. In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. Cancer Cell. 2013 Jul 08; 24(1):45-58.
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Allen DL, Metcalfe P, Kaplan C, Kekomaki R, de Haas M, Yusuf R, Ouwehand WH. Sensitivity of assays for the detection of HPA-1a antibodies: results of an international workshop demonstrating the impact of cation chelation from integrin aIIb?3 on three widely used assays. Vox Sang. 2013 Aug; 105(2):167-73.
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Allen DL, Abrahamsson S, Murphy MF, Roberts DJ. Human platelet antigen 1a epitopes are dependent on the cation-regulated conformation of integrin a(IIb)?(3) (GPIIb/IIIa). J Immunol Methods. 2012 Jan 31; 375(1-2):166-75.
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Allen DL, Samol J, Benjamin S, Verjee S, Tusold A, Murphy MF. Survey of the use and clinical effectiveness of HPA-1a/5b-negative platelet concentrates in proven or suspected platelet alloimmunization. Transfus Med. 2004 Dec; 14(6):409-17.
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Inwald DP, McDowall A, Peters MJ, Callard RE, Klein NJ. CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation. Circ Res. 2003 May 16; 92(9):1041-8.
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Kashani-Sabet M, Liu Y, Fong S, Desprez PY, Liu S, Tu G, Nosrati M, Handumrongkul C, Liggitt D, Thor AD, Debs RJ. Identification of gene function and functional pathways by systemic plasmid-based ribozyme targeting in adult mice. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3878-83.
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