Antigens, Human Platelet
"Antigens, Human Platelet" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Human alloantigens expressed only on platelets, specifically on platelet membrane glycoproteins. These platelet-specific antigens are immunogenic and can result in pathological reactions to transfusion therapy.
Descriptor ID |
D016824
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MeSH Number(s) |
D23.050.705.115
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Concept/Terms |
Antigens, Human Platelet- Antigens, Human Platelet
- Platelet Alloantigens
- Alloantigens, Platelet
- Platelet-Specific Antigens
- Platelet Specific Antigens
- Human Platelet Antigens
- Platelet Antigens, Human
- Antigens, Platelet-Specific
- Antigens, Platelet Specific
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Below are MeSH descriptors whose meaning is more general than "Antigens, Human Platelet".
Below are MeSH descriptors whose meaning is more specific than "Antigens, Human Platelet".
This graph shows the total number of publications written about "Antigens, Human Platelet" by people in this website by year, and whether "Antigens, Human Platelet" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antigens, Human Platelet" by people in Profiles.
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Allen DL, Metcalfe P, Kaplan C, Kekomaki R, de Haas M, Yusuf R, Ouwehand WH. Sensitivity of assays for the detection of HPA-1a antibodies: results of an international workshop demonstrating the impact of cation chelation from integrin aIIb?3 on three widely used assays. Vox Sang. 2013 Aug; 105(2):167-73.
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Allen DL, Abrahamsson S, Murphy MF, Roberts DJ. Human platelet antigen 1a epitopes are dependent on the cation-regulated conformation of integrin a(IIb)?(3) (GPIIb/IIIa). J Immunol Methods. 2012 Jan 31; 375(1-2):166-75.
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Solomon J, Swigris JJ, Brown KK. Myositis-related interstitial lung disease and antisynthetase syndrome. J Bras Pneumol. 2011 Jan-Feb; 37(1):100-9.
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Allen DL, Samol J, Benjamin S, Verjee S, Tusold A, Murphy MF. Survey of the use and clinical effectiveness of HPA-1a/5b-negative platelet concentrates in proven or suspected platelet alloimmunization. Transfus Med. 2004 Dec; 14(6):409-17.
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Norton A, Allen DL, Murphy MF. Review: platelet alloantigens and antibodies and their clinical significance. Immunohematology. 2004; 20(2):89-102.
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Watkins NA, Schaffner-Reckinger E, Allen DL, Howkins GJ, Brons NH, Smith GA, Metcalfe P, Murphy MF, Kieffer N, Ouwehand WH. HPA-1a phenotype-genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet beta 3 integrin that disrupts the HPA-1a epitope. Blood. 2002 Mar 01; 99(5):1833-9.
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Allen DL, Murphy MF. Evaluation of an enzyme-linked immunosorbent assay kit (GTI PakPlus) for the detection of antibodies against human platelet antigens. Transfus Med. 1999 Dec; 9(4):384-6.
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Allen DL, Floyd AP, Billson AL, Bell RA, Davis JG, Entwistle CC. Neonatal alloimmune thrombocytopenia due to anti-HPA-5b (Br(a), Zav(a), Hca): the importance of third-generation platelet antibody detection techniques, a case report. Transfus Med. 1992 Dec; 2(4):277-81.
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