 Digitonin
"Digitonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoside obtained from Digitalis purpurea; the aglycone is digitogenin which is bound to five sugars. Digitonin solubilizes lipids, especially in membranes and is used as a tool in cellular biochemistry, and reagent for precipitating cholesterol. It has no cardiac effects.
| Descriptor ID |
D004072
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| MeSH Number(s) |
D04.210.500.155.580.130.500.236 D09.408.180.261.236
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Digitonin".
Below are MeSH descriptors whose meaning is more specific than "Digitonin".
This graph shows the total number of publications written about "Digitonin" by people in this website by year, and whether "Digitonin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Digitonin" by people in Profiles.
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Wheeler JR, Matheny T, Jain S, Abrisch R, Parker R. Distinct stages in stress granule assembly and disassembly. Elife. 2016 09 07; 5.
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Taniai H, Hines IN, Bharwani S, Maloney RE, Nimura Y, Gao B, Flores SC, McCord JM, Grisham MB, Aw TY. Susceptibility of murine periportal hepatocytes to hypoxia-reoxygenation: role for NO and Kupffer cell-derived oxidants. Hepatology. 2004 Jun; 39(6):1544-52.
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Plutner H, Davidson HW, Saraste J, Balch WE. Morphological analysis of protein transport from the ER to Golgi membranes in digitonin-permeabilized cells: role of the P58 containing compartment. J Cell Biol. 1992 Dec; 119(5):1097-116.
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Heasley LE, Johnson GL. Regulation of protein kinase C by nerve growth factor, epidermal growth factor, and phorbol esters in PC12 pheochromocytoma cells. J Biol Chem. 1989 May 25; 264(15):8646-52.
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Steiner C, Dahl R, Sherman N, Trowbridge M, Vatter A, Robbins R, Draznin B. Somatostatin receptors are biologically active before they are inserted into the plasma membrane. Endocrinology. 1986 Feb; 118(2):766-72.
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