 Th2 Cells
"Th2 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of helper-inducer T-lymphocytes which synthesize and secrete the INTERLEUKINS IL-4; IL-5; IL-6; and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses.
| Descriptor ID |
D018418
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| MeSH Number(s) |
A11.118.637.555.567.550.500.400.905 A11.118.637.555.567.569.200.400.905 A11.118.637.555.567.569.500.400.905 A15.145.229.637.555.567.550.500.400.750 A15.145.229.637.555.567.569.200.400.750 A15.145.229.637.555.567.569.500.400.750 A15.382.490.555.567.550.500.400.905 A15.382.490.555.567.569.200.400.905 A15.382.490.555.567.569.500.400.905
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| Concept/Terms |
Th2 Cells- Th2 Cells
- Cell, Th2
- Cells, Th2
- Th2 Cell
- T Helper 2 Cells
- TH-2 Cells
- Cell, TH-2
- Cells, TH-2
- TH 2 Cells
- TH-2 Cell
- T Helper2 Cells
- Cell, T Helper2
- Cells, T Helper2
- T Helper2 Cell
- Type-2 Helper T Cells
- Type 2 Helper T Cells
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Below are MeSH descriptors whose meaning is more general than "Th2 Cells".
- Anatomy [A]
- Cells [A11]
- Blood Cells [A11.118]
- Leukocytes [A11.118.637]
- Leukocytes, Mononuclear [A11.118.637.555]
- Lymphocytes [A11.118.637.555.567]
- Lymphocyte Subsets [A11.118.637.555.567.550]
- T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
- Th2 Cells [A11.118.637.555.567.550.500.400.905]
- T-Lymphocytes [A11.118.637.555.567.569]
- CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.200.400]
- Th2 Cells [A11.118.637.555.567.569.200.400.905]
- T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
- Th2 Cells [A11.118.637.555.567.569.500.400.905]
- Hemic and Immune Systems [A15]
- Blood [A15.145]
- Blood Cells [A15.145.229]
- Leukocytes [A15.145.229.637]
- Leukocytes, Mononuclear [A15.145.229.637.555]
- Lymphocytes [A15.145.229.637.555.567]
- Lymphocyte Subsets [A15.145.229.637.555.567.550]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
- Th2 Cells [A15.145.229.637.555.567.550.500.400.750]
- T-Lymphocytes [A15.145.229.637.555.567.569]
- CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.200.400]
- Th2 Cells [A15.145.229.637.555.567.569.200.400.750]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
- Th2 Cells [A15.145.229.637.555.567.569.500.400.750]
- Immune System [A15.382]
- Leukocytes [A15.382.490]
- Leukocytes, Mononuclear [A15.382.490.555]
- Lymphocytes [A15.382.490.555.567]
- Lymphocyte Subsets [A15.382.490.555.567.550]
- T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
- Th2 Cells [A15.382.490.555.567.550.500.400.905]
- T-Lymphocytes [A15.382.490.555.567.569]
- CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.200.400]
- Th2 Cells [A15.382.490.555.567.569.200.400.905]
- T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]
- Th2 Cells [A15.382.490.555.567.569.500.400.905]
Below are MeSH descriptors whose meaning is more specific than "Th2 Cells".
This graph shows the total number of publications written about "Th2 Cells" by people in this website by year, and whether "Th2 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 2 | 0 | 2 | | 1998 | 1 | 1 | 2 | | 2000 | 2 | 1 | 3 | | 2001 | 1 | 1 | 2 | | 2002 | 2 | 0 | 2 | | 2003 | 6 | 3 | 9 | | 2004 | 6 | 1 | 7 | | 2005 | 3 | 4 | 7 | | 2006 | 5 | 5 | 10 | | 2007 | 3 | 2 | 5 | | 2008 | 4 | 3 | 7 | | 2009 | 1 | 4 | 5 | | 2010 | 6 | 2 | 8 | | 2011 | 3 | 7 | 10 | | 2012 | 4 | 3 | 7 | | 2013 | 1 | 5 | 6 | | 2014 | 6 | 2 | 8 | | 2015 | 3 | 0 | 3 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 3 | 4 | | 2018 | 0 | 3 | 3 | | 2019 | 4 | 1 | 5 | | 2020 | 1 | 2 | 3 | | 2021 | 0 | 3 | 3 | | 2022 | 0 | 2 | 2 | | 2023 | 1 | 1 | 2 | | 2024 | 1 | 3 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Th2 Cells" by people in Profiles.
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Gorska MM. Update on type 2 immunity. J Allergy Clin Immunol. 2025 Feb; 155(2):327-335.
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Fonseca Balladares DC, Kassa B, Mickael C, Kumar R, Nolan K, Menezes TCF, Lee MH, Lau-Xiao AM, Molofsky AB, Wells E, Graham BB. Intrapulmonary T Cells Are Sufficient for Schistosoma-Induced Pulmonary Hypertension. Int J Mol Sci. 2024 Aug 24; 25(17).
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Papadopoulos NG, Bacharier LB, Jackson DJ, Deschildre A, Phipatanakul W, Szefler SJ, Gall R, Ledanois O, Jacob-Nara JA, Sacks H. Type 2 Inflammation and Asthma in Children: A Narrative Review. J Allergy Clin Immunol Pract. 2024 Sep; 12(9):2310-2324.
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Greuter T, Straumann A, Fernandez-Marrero Y, Germic N, Hosseini A, Chanwangpong A, Yousefi S, Simon D, Collins MH, Bussmann C, Chehade M, Dellon ES, Furuta GT, Gonsalves N, Hirano I, Moawad FJ, Biedermann L, Safroneeva E, Schoepfer AM, Simon HU. A Multicenter Long-Term Cohort Study of Eosinophilic Esophagitis Variants and Their Progression to Eosinophilic Esophagitis Over Time. Clin Transl Gastroenterol. 2024 Apr 01; 15(4):e00664.
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Bao K, Isik Can U, Miller MM, Brown IK, Dell'Aringa M, Dooms H, Seibold MA, Scott-Browne J, Lee Reinhardt R. A bifurcated role for c-Maf in Th2 and Tfh2 cells during helminth infection. Mucosal Immunol. 2023 06; 16(3):357-372.
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Yang B, Wilkie H, Das M, Timilshina M, Bainter W, Woods B, Daya M, Boorgula MP, Mathias RA, Lai P, Petty CR, Weller E, Harb H, Chatila TA, Leung DYM, Beck LA, Simpson EL, Hata TR, Barnes KC, Phipatanakul W, Leyva-Castillo JM, Geha RS. The IL-4Ra Q576R polymorphism is associated with increased severity of atopic dermatitis and exaggerates allergic skin inflammation in mice. J Allergy Clin Immunol. 2023 05; 151(5):1296-1306.e7.
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Kabat AM, Hackl A, Sanin DE, Zeis P, Grzes KM, Baixauli F, Kyle R, Caputa G, Edwards-Hicks J, Villa M, Rana N, Curtis JD, Castoldi A, Cupovic J, Dreesen L, Sibilia M, Pospisilik JA, Urban JF, Grün D, Pearce EL, Pearce EJ. Resident TH2 cells orchestrate adipose tissue remodeling at a site adjacent to infection. Sci Immunol. 2022 10 21; 7(76):eadd3263.
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Verma M, Verma D, Alam R. Role of type-2 innate lymphoid cells (ILC2s) in type-2 asthma. Curr Opin Allergy Clin Immunol. 2022 02 01; 22(1):29-35.
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Schröder A, Lunding LP, Zissler UM, Vock C, Webering S, Ehlers JC, Orinska Z, Chaker A, Schmidt-Weber CB, Lang NJ, Schiller HB, Mall MA, Fehrenbach H, Dinarello CA, Wegmann M. IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33. Allergy. 2022 03; 77(3):856-869.
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Nganou-Makamdop K, Talla A, Sharma AA, Darko S, Ransier A, Laboune F, Chipman JG, Beilman GJ, Hoskuldsson T, Fourati S, Schmidt TE, Arumugam S, Lima NS, Moon D, Callisto S, Schoephoerster J, Tomalka J, Mugyenyi P, Ssali F, Muloma P, Ssengendo P, Leda AR, Cheu RK, Flynn JK, Morou A, Brunet-Ratnasingham E, Rodriguez B, Lederman MM, Kaufmann DE, Klatt NR, Kityo C, Brenchley JM, Schacker TW, Sekaly RP, Douek DC. Translocated microbiome composition determines immunological outcome in treated HIV infection. Cell. 2021 07 22; 184(15):3899-3914.e16.
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