 Complement C4b
"Complement C4b" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
| Descriptor ID |
D015935
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| MeSH Number(s) |
D12.776.124.486.274.350.260
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| Concept/Terms |
Complement C4b- Complement C4b
- C4b, Complement
- Complement 4b
- Complement Component 4b
- Component 4b, Complement
- C4b Complement
- Complement, C4b
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Below are MeSH descriptors whose meaning is more general than "Complement C4b".
Below are MeSH descriptors whose meaning is more specific than "Complement C4b".
This graph shows the total number of publications written about "Complement C4b" by people in this website by year, and whether "Complement C4b" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Complement C4b" by people in Profiles.
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Yuan X, Yu J, Gerber G, Chaturvedi S, Cole M, Chen H, Metjian A, Sperati CJ, Braunstein EM, Brodsky RA. Ex vivo assays to detect complement activation in complementopathies. Clin Immunol. 2020 12; 221:108616.
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Faria B, Can?o P, Cai Q, Henriques C, Matos AC, Poppelaars F, Gaya da Costa M, Daha MR, Silva R, Pestana M, Seelen MA. Arteriolar C4d in IgA Nephropathy: A Cohort Study. Am J Kidney Dis. 2020 11; 76(5):669-678.
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Wang HD, Fidder SAJ, Miller DT, Furtm?ller GJ, Ahmadi AR, N?gele F, Lopez J, Quan A, Budihardjo J, Lough DM, Akpinarli B, Etra JW, Vasilic D, Raimondi G, Lee WPA, Montgomery RA, Sun Z, Brandacher G. Desensitization and Prevention of Antibody-Mediated Rejection in Vascularized Composite Allotransplantation by Syngeneic Hematopoietic Stem Cell Transplantation. Transplantation. 2018 04; 102(4):593-600.
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Laskin BL, Maisel J, Goebel J, Yin HJ, Luo G, Khoury JC, Davies SM, Jodele S. Renal arteriolar C4d deposition: a novel characteristic of hematopoietic stem cell transplantation-associated thrombotic microangiopathy. Transplantation. 2013 Jul 27; 96(2):217-23.
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Xu Y, Galambos C, Reyes-M?gica M, Miller SA, Zeevi A, Webber SA, Feingold B. Utility of C4d immunostaining in the first year after pediatric and young adult heart transplantation. J Heart Lung Transplant. 2013 Jan; 32(1):92-7.
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Chang A, Moore JM, Cowan ML, Josephson MA, Chon WJ, Sciammas R, Du Z, Marino SR, Meehan SM, Millis M, David MZ, Williams JW, Chong AS. Plasma cell densities and glomerular filtration rates predict renal allograft outcomes following acute rejection. Transpl Int. 2012 Oct; 25(10):1050-8.
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Musat AI, Agni RM, Wai PY, Pirsch JD, Lorentzen DF, Powell A, Leverson GE, Bellingham JM, Fernandez LA, Foley DP, Mezrich JD, D'Alessandro AM, Lucey MR. The significance of donor-specific HLA antibodies in rejection and ductopenia development in ABO compatible liver transplantation. Am J Transplant. 2011 Mar; 11(3):500-10.
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Revelo MP, Stehlik J, Miller D, Snow GL, Everitt MD, Budge D, Bader FM, Alharethi RA, Gilbert EM, Reid BB, Selzman CH, Hammond ME, Kfoury AG. Antibody testing for cardiac antibody-mediated rejection: which panel correlates best with cardiovascular death? J Heart Lung Transplant. 2011 Feb; 30(2):144-50.
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Galambos C, Feingold B, Webber SA. Characterization of c4d immunostaining utilizing paraffin-embedded tissue of nonpresensitized pediatric heart transplant patients. Pediatr Dev Pathol. 2008 May-Jun; 11(3):181-4.
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Keller CE, Gamboa ET, Hays AP, Karlitz J, Lowe G, Green PH, Bhagat G. Fatal CNS vasculopathy in a patient with refractory celiac disease and lymph node cavitation. Virchows Arch. 2006 Feb; 448(2):209-13.
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