 Taurochenodeoxycholic Acid
"Taurochenodeoxycholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bile salt formed in the liver by conjugation of chenodeoxycholate with taurine, usually as the sodium salt. It acts as detergent to solubilize fats in the small intestine and is itself absorbed. It is used as a cholagogue and choleretic.
| Descriptor ID |
D013655
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| MeSH Number(s) |
D02.455.326.146.100.850.875.900.875 D02.886.645.600.055.850.800.900.875 D04.210.500.105.225.272.150.850 D04.210.500.105.225.272.925.875 D04.210.500.105.225.900.900.870 D04.210.500.221.430.342.300.900 D04.210.500.221.430.342.900.910 D04.210.500.221.430.873.920.900
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Taurochenodeoxycholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Taurochenodeoxycholic Acid".
This graph shows the total number of publications written about "Taurochenodeoxycholic Acid" by people in this website by year, and whether "Taurochenodeoxycholic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1998 | 1 | 1 | 2 | | 2005 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Taurochenodeoxycholic Acid" by people in Profiles.
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Hemingway HW, Moore AM, Olivencia-Yurvati AH, Romero SA. Effect of endoplasmic reticulum stress on endothelial ischemia-reperfusion injury in humans. Am J Physiol Regul Integr Comp Physiol. 2020 12 01; 319(6):R666-R672.
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Keestra-Gounder AM, Byndloss MX, Seyffert N, Young BM, Ch?vez-Arroyo A, Tsai AY, Cevallos SA, Winter MG, Pham OH, Tiffany CR, de Jong MF, Kerrinnes T, Ravindran R, Luciw PA, McSorley SJ, B?umler AJ, Tsolis RM. NOD1 and NOD2 signalling links ER stress with inflammation. Nature. 2016 Apr 21; 532(7599):394-7.
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Anderson CD, Upadhya G, Conzen KD, Jia J, Brunt EM, Tiriveedhi V, Xie Y, Ramachandran S, Mohanakumar T, Davidson NO, Chapman WC. Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts. Liver Transpl. 2011 Feb; 17(2):189-200.
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Sokol RJ, Dahl R, Devereaux MW, Yerushalmi B, Kobak GE, Gumpricht E. Human hepatic mitochondria generate reactive oxygen species and undergo the permeability transition in response to hydrophobic bile acids. J Pediatr Gastroenterol Nutr. 2005 Aug; 41(2):235-43.
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Shivaram KN, Winklhofer-Roob BM, Straka MS, Devereaux MW, Everson G, Mierau GW, Sokol RJ. The effect of idebenone, a coenzyme Q analogue, on hydrophobic bile acid toxicity to isolated rat hepatocytes and hepatic mitochondria. Free Radic Biol Med. 1998 Sep; 25(4-5):480-92.
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Sokol RJ, McKim JM, Goff MC, Ruyle SZ, Devereaux MW, Han D, Packer L, Everson G. Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat. Gastroenterology. 1998 Jan; 114(1):164-74.
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Sokol RJ, Winklhofer-Roob BM, Devereaux MW, McKim JM. Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids. Gastroenterology. 1995 Oct; 109(4):1249-56.
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