 Taurocholic Acid
"Taurocholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.
| Descriptor ID |
D013656
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| MeSH Number(s) |
D02.455.326.146.100.850.875 D02.886.645.600.055.850.800 D04.210.500.105.225.900 D04.210.500.221.430.873
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Taurocholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Taurocholic Acid".
This graph shows the total number of publications written about "Taurocholic Acid" by people in this website by year, and whether "Taurocholic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 | | 1996 | 0 | 2 | 2 | | 1997 | 1 | 3 | 4 | | 2000 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2015 | 1 | 1 | 2 |
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Below are the most recent publications written about "Taurocholic Acid" by people in Profiles.
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Moore HB, Moore EE, Lawson PJ, Gonzalez E, Fragoso M, Morton AP, Gamboni F, Chapman MP, Sauaia A, Banerjee A, Silliman CC. Fibrinolysis shutdown phenotype masks changes in rodent coagulation in tissue injury versus hemorrhagic shock. Surgery. 2015 Aug; 158(2):386-92.
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Wiener G, Moore HB, Moore EE, Gonzalez E, Diamond S, Zhu S, D'Alessandro A, Banerjee A. Shock releases bile acid inducing platelet inhibition and fibrinolysis. J Surg Res. 2015 May 15; 195(2):390-5.
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Sun AQ, Balasubramaniyan N, Xu K, Liu CJ, Ponamgi VM, Liu H, Suchy FJ. Protein-protein interactions and membrane localization of the human organic solute transporter. Am J Physiol Gastrointest Liver Physiol. 2007 Jun; 292(6):G1586-93.
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Sun AQ, Balasubramaniyan N, Chen H, Shahid M, Suchy FJ. Identification of functionally relevant residues of the rat ileal apical sodium-dependent bile acid cotransporter. J Biol Chem. 2006 Jun 16; 281(24):16410-8.
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Anwer MS, Gillin H, Mukhopadhyay S, Balasubramaniyan N, Suchy FJ, Ananthanarayanan M. Dephosphorylation of Ser-226 facilitates plasma membrane retention of Ntcp. J Biol Chem. 2005 Sep 30; 280(39):33687-92.
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Arrese M, Trauner M, Ananthanarayanan M, Pizarro M, Sol?s N, Accatino L, Soroka C, Boyer JL, Karpen SJ, Miquel JF, Suchy FJ. Down-regulation of the Na+/taurocholate cotransporting polypeptide during pregnancy in the rat. J Hepatol. 2003 Feb; 38(2):148-55.
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Webster CR, Srinivasulu U, Ananthanarayanan M, Suchy FJ, Anwer MS. Protein kinase B/Akt mediates cAMP- and cell swelling-stimulated Na+/taurocholate cotransport and Ntcp translocation. J Biol Chem. 2002 Aug 09; 277(32):28578-83.
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Sun AQ, Arrese MA, Zeng L, Swaby I, Zhou MM, Suchy FJ. The rat liver Na(+)/bile acid cotransporter. Importance of the cytoplasmic tail to function and plasma membrane targeting. J Biol Chem. 2001 Mar 02; 276(9):6825-33.
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Agellon LB, Torchia EC. Intracellular transport of bile acids. Biochim Biophys Acta. 2000 Jun 26; 1486(1):198-209.
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Torchia EC, Agellon LB. Bile acid-induced morphological changes in hepatoma cells with elevated sodium-dependent bile acid uptake capacity. Eur J Cell Biol. 1997 Oct; 74(2):190-6.
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