 Deoxycholic Acid
"Deoxycholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
| Descriptor ID |
D003840
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| MeSH Number(s) |
D04.210.500.105.225.272 D04.210.500.221.430.342
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| Concept/Terms |
Deoxycholic Acid- Deoxycholic Acid
- Acid, Deoxycholic
- Desoxycholic Acid
- Acid, Desoxycholic
- Dihydroxycholanoic Acid
- Acid, Dihydroxycholanoic
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Below are MeSH descriptors whose meaning is more general than "Deoxycholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Deoxycholic Acid".
This graph shows the total number of publications written about "Deoxycholic Acid" by people in this website by year, and whether "Deoxycholic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2021 | 0 | 3 | 3 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Deoxycholic Acid" by people in Profiles.
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Jovanovich A, Cai X, Frazier R, Bundy JD, He J, Rao P, Lora C, Dobre M, Go A, Shafi T, Feldman HI, Rhee EP, Miyazaki M, Isakova T, Chonchol M. Deoxycholic Acid and Coronary Artery Calcification in the Chronic Renal Insufficiency Cohort. J Am Heart Assoc. 2022 04 05; 11(7):e022891.
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Gergen AK, Jarrett MJ, Li A, Meng X, Pratap A, Fullerton DA, Weyant MJ. Toll-like Receptor 4 Mediates Reflux-Induced Inflammation in a Murine Reflux Model. Semin Thorac Cardiovasc Surg. 2022; 34(4):1324-1335.
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Miyazaki-Anzai S, Masuda M, Shiozaki Y, Keenan AL, Chonchol M, Kremoser C, Miyazaki M. Free Deoxycholic Acid Exacerbates Vascular Calcification in CKD through ER Stress-Mediated ATF4 Activation. Kidney360. 2021 May; 2(5):857-868.
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Gergen AK, Jarrett MJ, Li A, Cheng L, Tilva KR, Madsen HJ, Meng X, Fullerton DA, Weyant MJ. Expression of Adhesion Molecules in a Gastroduodenal Reflux Murine Model. Ann Thorac Surg. 2022 03; 113(3):926-933.
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Wipf A, Lofgreen S, Miller DD, Farah RS. Novel Use of Deoxycholic Acid for Adiposis Dolorosa (Dercum Disease). Dermatol Surg. 2019 12; 45(12):1718-1720.
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Jovanovich A, Isakova T, Block G, Stubbs J, Smits G, Chonchol M, Miyazaki M. Deoxycholic Acid, a Metabolite of Circulating Bile Acids, and Coronary Artery Vascular Calcification in CKD. Am J Kidney Dis. 2018 01; 71(1):27-34.
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Wang GS, Banerji S, Roussil TK, Heard KJ. Survival after amphotericin B overdose treated with plasmapheresis. Ann Pharmacother. 2013 Feb; 47(2):e9.
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Chafe SC, Pierce JB, Mangroo D. Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation. PLoS One. 2012; 7(8):e42501.
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Roesly HB, Khan MR, Chen HD, Hill KA, Narendran N, Watts GS, Chen X, Dvorak K. The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid. Am J Physiol Gastrointest Liver Physiol. 2012 Apr 15; 302(8):G864-72.
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Goldman A, Chen H, Khan MR, Roesly H, Hill KA, Shahidullah M, Mandal A, Delamere NA, Dvorak K. The Na+/H+ exchanger controls deoxycholic acid-induced apoptosis by a H+-activated, Na+-dependent ionic shift in esophageal cells. PLoS One. 2011; 6(8):e23835.
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