 Hexokinase
"Hexokinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of ATP and a D-hexose to ADP and a D-hexose 6-phosphate. D-Glucose, D-mannose, D-fructose, sorbitol, and D-glucosamine can act as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes been called glucokinase. (From Enzyme Nomenclature, 1992) EC 2.7.1.1.
| Descriptor ID |
D006593
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| MeSH Number(s) |
D08.811.913.696.620.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hexokinase".
Below are MeSH descriptors whose meaning is more specific than "Hexokinase".
This graph shows the total number of publications written about "Hexokinase" by people in this website by year, and whether "Hexokinase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hexokinase" by people in Profiles.
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Lee JY, Stevens RP, Pastukh VV, Pastukh VM, Kozhukhar N, Alexeyev MF, Reisz JA, Nerguizian D, D'Alessandro A, Koloteva A, Gwin MS, Roberts JT, Borchert GM, Wagener BM, Pittet JF, Graham BB, Stenmark KR, Stevens T. PFKFB3 Inhibits Fructose Metabolism in Pulmonary Microvascular Endothelial Cells. Am J Respir Cell Mol Biol. 2023 09; 69(3):340-354.
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Roberson PA, Kincheloe GN, Welles JE, Xu D, Sam-Clarke M, MacLean PS, Lang CH, Jefferson LS, Kimball SR. Glucose-Induced Activation of mTORC1 is Associated with Hexokinase2 Binding to Sestrins in HEK293T Cells. J Nutr. 2023 04; 153(4):988-998.
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Galbraith MD, Andrysik Z, Pandey A, Hoh M, Bonner EA, Hill AA, Sullivan KD, Espinosa JM. CDK8 Kinase Activity Promotes Glycolysis. Cell Rep. 2017 Nov 07; 21(6):1495-1506.
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Perkins M, Wolf AB, Chavira B, Shonebarger D, Meckel JP, Leung L, Ballina L, Ly S, Saini A, Jones TB, Vallejo J, Jentarra G, Valla J. Altered Energy Metabolism Pathways in the Posterior Cingulate in Young Adult Apolipoprotein E ?4 Carriers. J Alzheimers Dis. 2016 04 23; 53(1):95-106.
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Kelly G, Sade N, Attia Z, Secchi F, Zwieniecki M, Holbrook NM, Levi A, Alchanatis V, Moshelion M, Granot D. Relationship between hexokinase and the aquaporin PIP1 in the regulation of photosynthesis and plant growth. PLoS One. 2014; 9(2):e87888.
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Kelly G, Moshelion M, David-Schwartz R, Halperin O, Wallach R, Attia Z, Belausov E, Granot D. Hexokinase mediates stomatal closure. Plant J. 2013 Sep; 75(6):977-88.
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Caino MC, Chae YC, Vaira V, Ferrero S, Nosotti M, Martin NM, Weeraratna A, O'Connell M, Jernigan D, Fatatis A, Languino LR, Bosari S, Altieri DC. Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells. J Clin Invest. 2013 Jul; 123(7):2907-20.
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Gayathri Devi D, Cibin TR, Ramaiah D, Abraham A. Bis(3,5-diiodo-2,4,6-trihydroxyphenyl)squaraine: a novel candidate in photodynamic therapy for skin cancer models in vivo. J Photochem Photobiol B. 2008 Sep 18; 92(3):153-9.
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Kappy MS, Drake A, Gao D, Ratliff R. Assessing adrenal function in primary care settings with a single sample subcutaneous glucagon test. J Pediatr. 2006 Nov; 149(5):682-6.
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Magnusson AL, Powell T, Wennergren M, Jansson T. Glucose metabolism in the human preterm and term placenta of IUGR fetuses. Placenta. 2004 Apr; 25(4):337-46.
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