 Choline Kinase
"Choline Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that is active in the first step of choline phosphoglyceride (lecithin) biosynthesis by catalyzing the phosphorylation of choline to phosphorylcholine in the presence of ATP. Ethanolamine and its methyl and ethyl derivatives can also act as acceptors. EC 2.7.1.32.
| Descriptor ID |
D002797
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| MeSH Number(s) |
D08.811.913.696.620.155
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| Concept/Terms |
Choline Kinase- Choline Kinase
- Kinase, Choline
- Choline Phosphokinase
- Phosphokinase, Choline
- ATP Choline Transphosphatase
- Choline Transphosphatase, ATP
- Transphosphatase, ATP Choline
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Below are MeSH descriptors whose meaning is more general than "Choline Kinase".
Below are MeSH descriptors whose meaning is more specific than "Choline Kinase".
This graph shows the total number of publications written about "Choline Kinase" by people in this website by year, and whether "Choline Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Choline Kinase" by people in Profiles.
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Bhaduri S, Kelly CL, Lesbats C, Sharkey J, Ressel L, Mukherjee S, Platt MD, Delikatny EJ, Poptani H. Metabolic changes in glioblastomas in response to choline kinase inhibition: In vivo MRS in rodent models. NMR Biomed. 2023 03; 36(3):e4855.
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Bansal A, Harris RA, DeGrado TR. Choline phosphorylation and regulation of transcription of choline kinase a in hypoxia. J Lipid Res. 2012 Jan; 53(1):149-57.
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Darpolor MM, Kennealey PT, Le HC, Zakian KL, Ackerstaff E, Rizwan A, Chen JH, Sambol EB, Schwartz GK, Singer S, Koutcher JA. Preclinical study of treatment response in HCT-116 cells and xenografts with (1) H-decoupled (31) P MRS. NMR Biomed. 2011 Nov; 24(9):1159-68.
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Cheng J, Weber JD, Baldassare JJ, Raben DM. Ablation of Go alpha-subunit results in a transformed phenotype and constitutively active phosphatidylcholine-specific phospholipase C. J Biol Chem. 1997 Jul 11; 272(28):17312-9.
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