Thymidine Kinase
"Thymidine Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of ATP and thymidine to ADP and thymidine 5'-phosphate. Deoxyuridine can also act as an acceptor and dGTP as a donor. (From Enzyme Nomenclature, 1992) EC 2.7.1.21.
Descriptor ID |
D013937
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MeSH Number(s) |
D08.811.913.696.620.750
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Concept/Terms |
Thymidine Kinase- Thymidine Kinase
- Kinase, Thymidine
- Deoxypyrimidine Kinase
- Kinase, Deoxypyrimidine
- Deoxythymidine Kinase
- Kinase, Deoxythymidine
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Below are MeSH descriptors whose meaning is more general than "Thymidine Kinase".
Below are MeSH descriptors whose meaning is more specific than "Thymidine Kinase".
This graph shows the total number of publications written about "Thymidine Kinase" by people in this website by year, and whether "Thymidine Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 | 1996 | 0 | 1 | 1 | 1997 | 0 | 1 | 1 | 1998 | 0 | 1 | 1 | 1999 | 0 | 1 | 1 | 2000 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thymidine Kinase" by people in Profiles.
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Hashemi M, Fallah A, Aghayan HR, Arjmand B, Yazdani N, Verdi J, Ghodsi SM, Miri SM, Hadjighassem M. A New Approach in Gene Therapy of Glioblastoma Multiforme: Human Olfactory Ensheathing Cells as a Novel Carrier for Suicide Gene Delivery. Mol Neurobiol. 2016 10; 53(8):5118-28.
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Swan AA, Clutton JE, Chary PK, Cook SG, Liu GG, Drew MR. Characterization of the role of adult neurogenesis in touch-screen discrimination learning. Hippocampus. 2014 Dec; 24(12):1581-91.
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Alegre MM, Weyant MJ, Bennett DT, Yu JA, Ramsden MK, Elnaggar A, Robison RA, O'Neill KL. Serum detection of thymidine kinase 1 as a means of early detection of lung cancer. Anticancer Res. 2014 May; 34(5):2145-51.
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Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS. In vivo evaluation of 2'-deoxy-2'-[(18)F]fluoro-5-iodo-1-beta-D-arabinofuranosyluracil ([18F]FIAU) and 2'-deoxy-2'-[18F]fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil ([18F]FEAU) as markers for suicide gene expression. Eur J Nucl Med Mol Imaging. 2007 Jun; 34(6):822-9.
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Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS. Synthesis and evaluation of 2'-deoxy-2'-18F-fluoro-5-fluoro-1-beta-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression. J Nucl Med. 2004 Dec; 45(12):2063-9.
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Liu G, Beggs H, J?rgensen C, Park HT, Tang H, Gorski J, Jones KR, Reichardt LF, Wu J, Rao Y. Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction. Nat Neurosci. 2004 Nov; 7(11):1222-32.
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Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS. Synthesis of 2'-deoxy-2'-[18F]fluoro-5-bromo-1-beta-D-arabinofuranosyluracil ([18F]-FBAU) and 2'-deoxy-2'-[18F]fluoro-5-chloro-1-beta-D-arabinofuranosyl-uracil ([18F]-FCAU), and their biological evaluation as markers for gene expression. Nucl Med Biol. 2004 May; 31(4):399-405.
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Alauddin MM, Shahinian A, Gordon EM, Conti PS. Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model. Mol Imaging. 2004 Apr; 3(2):76-84.
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Tjuvajev JG, Doubrovin M, Akhurst T, Cai S, Balatoni J, Alauddin MM, Finn R, Bornmann W, Thaler H, Conti PS, Blasberg RG. Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression. J Nucl Med. 2002 Aug; 43(8):1072-83.
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Alauddin MM, Shahinian A, Gordon EM, Conti PS. Evaluation of 2'-deoxy-2'-flouro-5-methyl-1-beta-D-arabinofuranosyluracil as a potential gene imaging agent for HSV-tk expression in vivo. Mol Imaging. 2002 Apr-Jun; 1(2):74-81.
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