Single-Domain Antibodies
"Single-Domain Antibodies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An immunoglobulin fragment composed of one variable domain from an IMMUNOGLOBULIN HEAVY CHAIN or IMMUNOGLOBULIN LIGHT CHAIN.
Descriptor ID |
D061905
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MeSH Number(s) |
D12.644.541.500.650.500.900 D12.776.124.486.485.680.650.500.900 D12.776.124.790.651.680.650.500.900 D12.776.377.715.548.680.650.500.897
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Concept/Terms |
VHH Immunoglobulin Fragments- VHH Immunoglobulin Fragments
- Fragments, VHH Immunoglobulin
- Immunoglobulin Fragments, VHH
- Nanobodies
- VHH Fragments
- Fragments, VHH
VNAR Immunoglobulin Fragments- VNAR Immunoglobulin Fragments
- Fragments, VNAR Immunoglobulin
- Immunoglobulin Fragments, VNAR
- VNAR Fragments
- Fragments, VNAR
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Below are MeSH descriptors whose meaning is more general than "Single-Domain Antibodies".
Below are MeSH descriptors whose meaning is more specific than "Single-Domain Antibodies".
This graph shows the total number of publications written about "Single-Domain Antibodies" by people in this website by year, and whether "Single-Domain Antibodies" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2018 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Single-Domain Antibodies" by people in Profiles.
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Scully M, de la Rubia J, Pavenski K, Metjian A, Kn?bl P, Peyvandi F, Cataland S, Coppo P, Kremer Hovinga JA, Minkue Mi Edou J, De Passos Sousa R, Callewaert F, Gunawardena S, Lin J. Long-term follow-up of patients treated with caplacizumab and safety and efficacy of repeat caplacizumab use: Post-HERCULES study. J Thromb Haemost. 2022 12; 20(12):2810-2822.
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Peyvandi F, Cataland S, Scully M, Coppo P, Knoebl P, Kremer Hovinga JA, Metjian A, de la Rubia J, Pavenski K, Minkue Mi Edou J, De Winter H, Callewaert F. Caplacizumab prevents refractoriness and mortality in acquired thrombotic thrombocytopenic purpura: integrated analysis. Blood Adv. 2021 04 27; 5(8):2137-2141.
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Knoebl P, Cataland S, Peyvandi F, Coppo P, Scully M, Kremer Hovinga JA, Metjian A, de la Rubia J, Pavenski K, Minkue Mi Edou J, De Winter H, Callewaert F. Efficacy and safety of open-label caplacizumab in patients with exacerbations of acquired thrombotic thrombocytopenic purpura in the HERCULES study. J Thromb Haemost. 2020 02; 18(2):479-484.
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Ruoff K, Kilic T, Devant J, Koromyslova A, Ringel A, Hempelmann A, Geiss C, Graf J, Haas M, Roggenbach I, Hansman G. Structural Basis of Nanobodies Targeting the Prototype Norovirus. J Virol. 2019 03 15; 93(6).
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Scully M, Cataland SR, Peyvandi F, Coppo P, Kn?bl P, Kremer Hovinga JA, Metjian A, de la Rubia J, Pavenski K, Callewaert F, Biswas D, De Winter H, Zeldin RK. Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura. N Engl J Med. 2019 01 24; 380(4):335-346.
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Gulati S, Jin H, Masuho I, Orban T, Cai Y, Pardon E, Martemyanov KA, Kiser PD, Stewart PL, Ford CP, Steyaert J, Palczewski K. Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor. Nat Commun. 2018 05 18; 9(1):1996.
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Iljina M, Hong L, Horrocks MH, Ludtmann MH, Choi ML, Hughes CD, Ruggeri FS, Guilliams T, Buell AK, Lee JE, Gandhi S, Lee SF, Bryant CE, Vendruscolo M, Knowles TPJ, Dobson CM, De Genst E, Klenerman D. Nanobodies raised against monomeric ?-synuclein inhibit fibril formation and destabilize toxic oligomeric species. BMC Biol. 2017 07 03; 15(1):57.
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Lee ZB, Firnhaber C, Clarke J, DeDecker BS. Gene and library synthesis without amplification: polymerase step reaction (PSR). Biotechniques. 2015 Sep; 59(3):163-6.
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