 Uncoupling Protein 3
"Uncoupling Protein 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial uncoupling protein that is expressed in heart and skeletal muscle tissues. It functions to regulate tissue respiration, energy balance, and THERMOGENESIS. Mutations in the UCP3 gene are associated with OBESITY.
| Descriptor ID |
D000071247
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| MeSH Number(s) |
D12.776.157.530.937.598.875 D12.776.543.585.475.688.875 D12.776.543.585.937.696.875 D12.776.575.750.688.875
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| Concept/Terms |
Uncoupling Protein 3- Uncoupling Protein 3
- Uncoupling Protein-3
- Solute Carrier Family 25 Member 9
- UCP3 Protein
- SLC25A9 Protein
- Mitochondrial Uncoupling Protein 3
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Below are MeSH descriptors whose meaning is more general than "Uncoupling Protein 3".
Below are MeSH descriptors whose meaning is more specific than "Uncoupling Protein 3".
This graph shows the total number of publications written about "Uncoupling Protein 3" by people in this website by year, and whether "Uncoupling Protein 3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 3 | 3 | | 2010 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Uncoupling Protein 3" by people in Profiles.
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Hirasaka K, Mills EM, Haruna M, Bando A, Ikeda C, Abe T, Kohno S, Nowinski SM, Lago CU, Akagi K, Tochio H, Ohno A, Teshima-Kondo S, Okumura Y, Nikawa T. UCP3 is associated with Hax-1 in mitochondria in the presence of calcium ion. Biochem Biophys Res Commun. 2016 Mar 25; 472(1):108-13.
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Knaub LA, McCune S, Chicco AJ, Miller M, Moore RL, Birdsey N, Lloyd MI, Villarreal J, Keller AC, Watson PA, Reusch JE. Impaired response to exercise intervention in the vasculature in metabolic syndrome. Diab Vasc Dis Res. 2013 May; 10(3):222-38.
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Boyle KE, Canham JP, Consitt LA, Zheng D, Koves TR, Gavin TP, Holbert D, Neufer PD, Ilkayeva O, Muoio DM, Houmard JA. A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals. J Clin Endocrinol Metab. 2011 Mar; 96(3):775-81.
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Watson PA, Birdsey N, Huggins GS, Svensson E, Heppe D, Knaub L. Cardiac-specific overexpression of dominant-negative CREB leads to increased mortality and mitochondrial dysfunction in female mice. Am J Physiol Heart Circ Physiol. 2010 Dec; 299(6):H2056-68.
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Damcott CM, Feingold E, Moffett SP, Barmada MM, Marshall JA, Hamman RF, Ferrell RE. Genetic variation in uncoupling protein 3 is associated with dietary intake and body composition in females. Metabolism. 2004 Apr; 53(4):458-64.
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Calsbeek DJ, Thompson TL, Dahl JA, Stob NR, Brozinick JT, Hill JO, Hickey MS. Metabolic and anthropometric factors related to skeletal muscle UCP3 gene expression in healthy human adults. Am J Physiol Endocrinol Metab. 2002 Oct; 283(4):E631-7.
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Muoio DM, MacLean PS, Lang DB, Li S, Houmard JA, Way JM, Winegar DA, Corton JC, Dohm GL, Kraus WE. Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. J Biol Chem. 2002 Jul 19; 277(29):26089-97.
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Kimm SY, Glynn NW, Aston CE, Damcott CM, Poehlman ET, Daniels SR, Ferrell RE. Racial differences in the relation between uncoupling protein genes and resting energy expenditure. Am J Clin Nutr. 2002 Apr; 75(4):714-9.
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