Lubiprostone
"Lubiprostone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Member of a bicyclic fatty acid class of compounds derived from PROSTAGLANDIN E1 involved in chloride channel gating.
Descriptor ID |
D000068238
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MeSH Number(s) |
D10.251.355.325.050.500
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Concept/Terms |
Lubiprostone- Lubiprostone
- Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11alpha)-
RU 0211- RU 0211
- 0211, RU
- RU0211
- RU-0211
SPI 0211- SPI 0211
- 0211, SPI
- SPI0211
- SPI-0211
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Below are MeSH descriptors whose meaning is more general than "Lubiprostone".
Below are MeSH descriptors whose meaning is more specific than "Lubiprostone".
This graph shows the total number of publications written about "Lubiprostone" by people in this website by year, and whether "Lubiprostone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2013 | 0 | 2 | 2 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lubiprostone" by people in Profiles.
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Shaughnessy CA, Yadav S, Bratcher PE, Zeitlin PL. Receptor-mediated activation of CFTR via prostaglandin signaling pathways in the airway. Am J Physiol Lung Cell Mol Physiol. 2022 03 01; 322(3):L305-L314.
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Colgan SP. Swimming through the gut: implications of fluid transport on the microbiome. Dig Dis Sci. 2013 Mar; 58(3):602-3.
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Schiffhauer ES, Vij N, Kovbasnjuk O, Kang PW, Walker D, Lee S, Zeitlin PL. Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelia. Am J Physiol Lung Cell Mol Physiol. 2013 Mar 01; 304(5):L324-31.
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Keely S, Kelly CJ, Weissmueller T, Burgess A, Wagner BD, Robertson CE, Harris JK, Colgan SP. Activated fluid transport regulates bacterial-epithelial interactions and significantly shifts the murine colonic microbiome. Gut Microbes. 2012 May-Jun; 3(3):250-60.
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MacDonald KD, McKenzie KR, Henderson MJ, Hawkins CE, Vij N, Zeitlin PL. Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice. Am J Physiol Lung Cell Mol Physiol. 2008 Nov; 295(5):L933-40.
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