 Neurokinin-1 Receptor Antagonists
"Neurokinin-1 Receptor Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit or block the activity of NEUROKININ-1 RECEPTORS.
| Descriptor ID |
D064729
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| MeSH Number(s) |
D27.505.519.625.487 D27.505.696.577.487
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| Concept/Terms |
Neurokinin-1 Receptor Antagonists- Neurokinin-1 Receptor Antagonists
- Antagonists, Neurokinin-1 Receptor
- Neurokinin 1 Receptor Antagonists
- Receptor Antagonists, Neurokinin-1
- Neuroleukin-1 Receptor Blockers
- Blockers, Neuroleukin-1 Receptor
- Neuroleukin 1 Receptor Blockers
- Receptor Blockers, Neuroleukin-1
- Substance P Receptor Antagonists
- Tachykinin Receptor 1 Antagonists
- Tachykinin Receptor 1 Blockers
- Neurokinin-1 Receptor Blockers
- Blockers, Neurokinin-1 Receptor
- Neurokinin 1 Receptor Blockers
- Receptor Blockers, Neurokinin-1
- Substance P Receptor Blockers
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Below are MeSH descriptors whose meaning is more general than "Neurokinin-1 Receptor Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Neurokinin-1 Receptor Antagonists".
This graph shows the total number of publications written about "Neurokinin-1 Receptor Antagonists" by people in this website by year, and whether "Neurokinin-1 Receptor Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2013 | 0 | 2 | 2 | | 2014 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Neurokinin-1 Receptor Antagonists" by people in Profiles.
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Bubak AN, Como CN, Blackmon AM, Frietze S, Mescher T, Jones D, Cohrs RJ, Paucek P, Baird NL, Nagel MA. Varicella Zoster Virus Induces Nuclear Translocation of the Neurokinin-1 Receptor, Promoting Lamellipodia Formation and Viral Spread in Spinal Astrocytes. J Infect Dis. 2018 09 08; 218(8):1324-1335.
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Kwako LE, Schwandt ML, Sells JR, Ramchandani VA, Hommer DW, George DT, Sinha R, Heilig M. Methods for inducing alcohol craving in individuals with co-morbid alcohol dependence and posttraumatic stress disorder: behavioral and physiological outcomes. Addict Biol. 2015 Jul; 20(4):733-46.
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Spitsin S, Tuluc F, Meshki J, Ping Lai J, Tustin Iii R, Douglas SD. Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor. Neuroimmunomodulation. 2013; 20(5):247-55.
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Schwartz L, Spitsin SV, Meshki J, Tuluc F, Douglas SD, Wolfe JH. Substance P enhances HIV-1 infection in human fetal brain cell cultures expressing full-length neurokinin-1 receptor. J Neurovirol. 2013 Jun; 19(3):219-27.
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Manak MM, Moshkoff DA, Nguyen LT, Meshki J, Tebas P, Tuluc F, Douglas SD. Anti-HIV-1 activity of the neurokinin-1 receptor antagonist aprepitant and synergistic interactions with other antiretrovirals. AIDS. 2010 Nov 27; 24(18):2789-96.
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Meshki J, Douglas SD, Lai JP, Schwartz L, Kilpatrick LE, Tuluc F. Neurokinin 1 receptor mediates membrane blebbing in HEK293 cells through a Rho/Rho-associated coiled-coil kinase-dependent mechanism. J Biol Chem. 2009 Apr 03; 284(14):9280-9.
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Matsubara S, Swasey CH, Loader JE, Dakhama A, Joetham A, Ohnishi H, Balhorn A, Miyahara N, Takeda K, Gelfand EW. Estrogen determines sex differences in airway responsiveness after allergen exposure. Am J Respir Cell Mol Biol. 2008 May; 38(5):501-8.
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Dakhama A, Park JW, Taube C, El Gazzar M, Kodama T, Miyahara N, Takeda K, Kanehiro A, Balhorn A, Joetham A, Loader JE, Larsen GL, Gelfand EW. Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection. Am J Physiol Lung Cell Mol Physiol. 2005 Apr; 288(4):L761-70.
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Carpenter TC, Stenmark KR. Hypoxia decreases lung neprilysin expression and increases pulmonary vascular leak. Am J Physiol Lung Cell Mol Physiol. 2001 Oct; 281(4):L941-8.
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Evans CM, Belmonte KE, Costello RW, Jacoby DB, Gleich GJ, Fryer AD. Substance P-induced airway hyperreactivity is mediated by neuronal M(2) receptor dysfunction. Am J Physiol Lung Cell Mol Physiol. 2000 Sep; 279(3):L477-86.
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