 Giant Cell Arteritis
"Giant Cell Arteritis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)
| Descriptor ID |
D013700
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| MeSH Number(s) |
C10.114.875.700 C10.228.140.300.850.500 C14.907.253.946.700 C14.907.940.090.530 C14.907.940.907.700 C17.800.862.252 C20.111.258.962.800
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| Concept/Terms |
Giant Cell Arteritis- Giant Cell Arteritis
- Arteritides, Giant Cell
- Arteritis, Giant Cell
- Giant Cell Arteritides
- Arteritis, Giant Cell, Horton's
- Horton's Giant Cell Arteritis
- Horton Disease
- Horton Giant Cell Arteritis
- Horton's Disease
- Hortons Disease
- Arteritis, Giant Cell, Horton
- Giant Cell Arteritis, Horton
Temporal Arteritis- Temporal Arteritis
- Arteritides, Temporal
- Temporal Arteritides
- Arteritis, Temporal
Juvenile Temporal Arteritis- Juvenile Temporal Arteritis
- Arteritides, Juvenile Temporal
- Arteritis, Juvenile Temporal
- Juvenile Temporal Arteritides
- Temporal Arteritides, Juvenile
- Temporal Arteritis, Juvenile
Aortic Arteritis, Giant Cell- Aortic Arteritis, Giant Cell
- Giant Cell Aortitis, Horton's
- Giant Cell Aortitis
- Aortitis, Giant Cell
- Aortitides, Giant Cell
- Giant Cell Aortitides
- Giant Cell Aortic Arteritis
Cranial Arteritis- Cranial Arteritis
- Arteritides, Cranial
- Arteritis, Cranial
- Cranial Arteritides
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Below are MeSH descriptors whose meaning is more general than "Giant Cell Arteritis".
Below are MeSH descriptors whose meaning is more specific than "Giant Cell Arteritis".
This graph shows the total number of publications written about "Giant Cell Arteritis" by people in this website by year, and whether "Giant Cell Arteritis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2000 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 | | 2015 | 5 | 0 | 5 | | 2016 | 5 | 1 | 6 | | 2017 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 0 | 1 | | 2020 | 2 | 1 | 3 | | 2021 | 2 | 0 | 2 | | 2022 | 3 | 0 | 3 | | 2023 | 3 | 0 | 3 | | 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Giant Cell Arteritis" by people in Profiles.
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Labowsky M, Harnke B. The Set up and the Triggers: An Update on the Risk Factors for Giant Cell Arteritis. Curr Neurol Neurosci Rep. 2024 Dec 14; 25(1):11.
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Cunningham KY, Hur B, Gupta VK, Koster MJ, Weyand CM, Cuthbertson D, Khalidi NA, Koening CL, Langford CA, McAlear CA, Monach PA, Moreland LW, Pagnoux C, Rhee RL, Seo P, Merkel PA, Warrington KJ, Sung J. Plasma proteome profiling in giant cell arteritis. Ann Rheum Dis. 2024 Nov 14; 83(12):1762-1772.
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Cantoni E, Merelli I, Stefanoni D, Tomelleri A, Campochiaro C, Giordano V, Panigada M, Baldissera EM, Merlo Pich L, Natoli V, Ziogas A, Dom?nguez-Andr?s J, De Luca G, Mazza D, Zambrano S, Gnani D, Ferrarini M, Ferrero E, Agresti A, Vergani B, Leone BE, Cenci S, Ravelli A, Matucci-Cerinic M, D'Alessandro A, Joosten LAB, Dagna L, Netea MG, Molteni R, Cavalli G. Myelomonocytic cells in giant cell arteritis activate trained immunity programs sustaining inflammation and cytokine production. Rheumatology (Oxford). 2023 10 03; 62(10):3469-3479.
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Michailidou D, Grayson PC, Hermanson P, Chapa JAG, Cuthbertson D, Khalidi NA, Koening CL, Langford CA, McAlear CA, Moreland LW, Pagnoux C, Seo P, Sreih AG, Warrington KJ, Monach PA, Merkel PA, Lood C. Mitochondrial-mediated inflammation and platelet activation in giant cell arteritis. Clin Immunol. 2023 10; 255:109746.
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Michailidou D, Kuley R, Wang T, Hermanson P, Grayson PC, Cuthbertson D, Khalidi NA, Koening CL, Langford CA, McAlear CA, Moreland LW, Pagnoux C, Seo P, Specks U, Sreih AG, Warrington KJ, Monach PA, Merkel PA, Lood C. Neutrophil extracellular trap formation in anti-neutrophil cytoplasmic antibody-associated and large-vessel vasculitis. Clin Immunol. 2023 04; 249:109274.
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Nguyen AAK, Sammel AM, Mollan SP, Subramanian PS, Fraser CL. Giant Cell Arteritis Incidence During the COVID Pandemic. J Neuroophthalmol. 2024 Mar 01; 44(1):e62-e63.
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Michailidou D, Duvvuri B, Kuley R, Cuthbertson D, Grayson PC, Khalidi NA, Koening CL, Langford CA, McAlear CA, Moreland LW, Pagnoux C, Seo P, Specks U, Sreih AG, Warrington KJ, Mustelin T, Monach PA, Merkel PA, Lood C. Neutrophil activation in patients with anti-neutrophil cytoplasmic autoantibody-associated vasculitis and large-vessel vasculitis. Arthritis Res Ther. 2022 06 29; 24(1):160.
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Caton MT, Mark IT, Narsinh KH, Baker A, Cooke DL, Hetts SW, Dowd CF, Halbach VV, Higashida RT, Ko NU, Chung SA, Amans MR. Endovascular Therapy for Intracranial Giant Cell Arteritis : Systematic Review, Technical Considerations and the Effect of Intra-arterial Calcium Channel Blockers. Clin Neuroradiol. 2022 Dec; 32(4):1045-1056.
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Bubak AN, Mescher T, Mariani M, Frietze SE, Hassell JE, Niemeyer CS, Como CN, Burnet AM, Subramanian PS, Cohrs RJ, Mahalingam R, Nagel MA. Targeted RNA Sequencing of Formalin-Fixed, Paraffin-Embedded Temporal Arteries From Giant Cell Arteritis Cases Reveals Viral Signatures. Neurol Neuroimmunol Neuroinflamm. 2021 11; 8(6).
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Chung SH, Morcos MB, Pollock PS, Ng B. The U.S. Veterans Health Administration national giant cell arteritis (GCA) database cohort: incident ophthalmic complications in biopsy-negative GCA patients. Clin Rheumatol. 2021 Jul; 40(7):2829-2833.
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