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																		 Tartrate-Resistant Acid Phosphatase
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"Tartrate-Resistant Acid Phosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.
    
			 
				
				
					
						| Descriptor ID | D000071681 |  
						| MeSH Number(s) | D08.811.277.352.650.025.500 D08.811.277.352.650.625.862 |  
						| Concept/Terms | Tartrate-Resistant Acid PhosphataseTartrate-Resistant Acid PhosphataseAcid Phosphatase, Tartrate-ResistantPhosphatase, Tartrate-Resistant AcidTartrate Resistant Acid PhosphataseTRAcP
 TRAP Type 5 AcPaseTRAP Type 5 AcPaseAcid Phosphatase VPhosphatase V, AcidV, Acid PhosphataseAcPase VV, AcPaseType 5 Acid PhosphataseTartrate-Resistant Acid Phosphatase Type 5Tartrate Resistant Acid Phosphatase Type 5
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				Below are MeSH descriptors whose meaning is more general than "Tartrate-Resistant Acid Phosphatase". 
				Below are MeSH descriptors whose meaning is more specific than "Tartrate-Resistant Acid Phosphatase". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "Tartrate-Resistant Acid Phosphatase" by people in this website by year, and whether "Tartrate-Resistant Acid Phosphatase" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 2002 | 0 | 1 | 1 |  | 2008 | 0 | 1 | 1 |  | 2009 | 0 | 1 | 1 |  | 2021 | 0 | 1 | 1 |  | 2022 | 0 | 1 | 1 | 
 
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				Below are the most recent publications written about "Tartrate-Resistant Acid Phosphatase" by people in Profiles. 		
					
								
								Khrystoforova I, Shochat-Carvalho C, Harari R, Henke K, Woronowicz K, Harris MP, Karasik D. Zebrafish mutants reveal unexpected role of Lrp5 in osteoclast regulation. Front Endocrinol (Lausanne). 2022; 13:985304.
								Pin F, Prideaux M, Huot JR, Essex AL, Plotkin LI, Bonetto A, Bonewald LF. Non-bone metastatic cancers promote osteocyte-induced bone destruction. Cancer Lett. 2021 11 01; 520:80-90.
								Weinstein RS, Roberson PK, Manolagas SC. Giant osteoclast formation and long-term oral bisphosphonate therapy. N Engl J Med. 2009 Jan 01; 360(1):53-62.
								Norian JM, Zeitlian G, Adel G, Freeman RG, Santoro NF, Pal L. Low serum osteoprotegerin levels in premenopausal infertile women with low bone density: an association of relevance? Fertil Steril. 2009 Feb; 91(2):542-8.
								Pham L, Purcell P, Morse L, Stashenko P, Battaglino RA. Expression analysis of nha-oc/NHA2: a novel gene selectively expressed in osteoclasts. Gene Expr Patterns. 2007 Oct; 7(8):846-51.
								Sheu TJ, Schwarz EM, Martinez DA, O'Keefe RJ, Rosier RN, Zuscik MJ, Puzas JE. A phage display technique identifies a novel regulator of cell differentiation. J Biol Chem. 2003 Jan 03; 278(1):438-43. | 
																	
																		
																			
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