 Tartrate-Resistant Acid Phosphatase
"Tartrate-Resistant Acid Phosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.
| Descriptor ID |
D000071681
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| MeSH Number(s) |
D08.811.277.352.650.025.500 D08.811.277.352.650.625.862
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| Concept/Terms |
Tartrate-Resistant Acid Phosphatase- Tartrate-Resistant Acid Phosphatase
- Acid Phosphatase, Tartrate-Resistant
- Phosphatase, Tartrate-Resistant Acid
- Tartrate Resistant Acid Phosphatase
- TRAcP
TRAP Type 5 AcPase- TRAP Type 5 AcPase
- Acid Phosphatase V
- Phosphatase V, Acid
- V, Acid Phosphatase
- AcPase V
- V, AcPase
- Type 5 Acid Phosphatase
- Tartrate-Resistant Acid Phosphatase Type 5
- Tartrate Resistant Acid Phosphatase Type 5
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Below are MeSH descriptors whose meaning is more general than "Tartrate-Resistant Acid Phosphatase".
Below are MeSH descriptors whose meaning is more specific than "Tartrate-Resistant Acid Phosphatase".
This graph shows the total number of publications written about "Tartrate-Resistant Acid Phosphatase" by people in this website by year, and whether "Tartrate-Resistant Acid Phosphatase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2008 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tartrate-Resistant Acid Phosphatase" by people in Profiles.
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Khrystoforova I, Shochat-Carvalho C, Harari R, Henke K, Woronowicz K, Harris MP, Karasik D. Zebrafish mutants reveal unexpected role of Lrp5 in osteoclast regulation. Front Endocrinol (Lausanne). 2022; 13:985304.
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Pin F, Prideaux M, Huot JR, Essex AL, Plotkin LI, Bonetto A, Bonewald LF. Non-bone metastatic cancers promote osteocyte-induced bone destruction. Cancer Lett. 2021 11 01; 520:80-90.
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Norian JM, Zeitlian G, Adel G, Freeman RG, Santoro NF, Pal L. Low serum osteoprotegerin levels in premenopausal infertile women with low bone density: an association of relevance? Fertil Steril. 2009 Feb; 91(2):542-8.
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Pham L, Purcell P, Morse L, Stashenko P, Battaglino RA. Expression analysis of nha-oc/NHA2: a novel gene selectively expressed in osteoclasts. Gene Expr Patterns. 2007 Oct; 7(8):846-51.
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