 Decorin
"Decorin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.
| Descriptor ID |
D058575
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| MeSH Number(s) |
D09.698.735.700.750 D12.776.395.650.750.625 D12.776.395.650.875.500 D12.776.860.300.806.750
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| Concept/Terms |
Decorin- Decorin
- Bone Proteoglycan II
- Proteoglycan II, Bone
- DSPG-II
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Below are MeSH descriptors whose meaning is more general than "Decorin".
Below are MeSH descriptors whose meaning is more specific than "Decorin".
This graph shows the total number of publications written about "Decorin" by people in this website by year, and whether "Decorin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Decorin" by people in Profiles.
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Oshima K, Siddiqui N, Orfila JE, Carter D, Laing J, Han X, Zakharevich I, Iozzo RV, Ghasabyan A, Moore H, Zhang F, Linhardt RJ, Moore EE, Quillinan N, Schmidt EP, Herson PS, Hippensteel JA. A role for decorin in improving motor deficits after traumatic brain injury. Matrix Biol. 2024 Jan; 125:88-99.
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Aguado BA, Hartfield RM, Bushnell GG, Decker JT, Azarin SM, Nanavati D, Schipma MJ, Rao SS, Oakes RS, Zhang Y, Jeruss JS, Shea LD. Biomaterial Scaffolds as Pre-metastatic Niche Mimics Systemically Alter the Primary Tumor and Tumor Microenvironment. Adv Healthc Mater. 2018 05; 7(10):e1700903.
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Barker NM, Carrino DA, Caplan AI, Hurd WW, Liu JH, Tan H, Mesiano S. Proteoglycans in Leiomyoma and Normal Myometrium: Abundance, Steroid Hormone Control, and Implications for Pathophysiology. Reprod Sci. 2016 Mar; 23(3):302-9.
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Roberts JJ, Nicodemus GD, Greenwald EC, Bryant SJ. Degradation improves tissue formation in (un)loaded chondrocyte-laden hydrogels. Clin Orthop Relat Res. 2011 Oct; 469(10):2725-34.
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Krishna P, Regner M, Palko J, Liu F, Abramowitch S, Jiang J, Wells A. The effects of decorin and HGF-primed vocal fold fibroblasts in vitro and ex vivo in a porcine model of vocal fold scarring. Laryngoscope. 2010 Nov; 120(11):2247-57.
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Salinas CN, Anseth KS. Decorin moieties tethered into PEG networks induce chondrogenesis of human mesenchymal stem cells. J Biomed Mater Res A. 2009 Aug; 90(2):456-64.
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Maeda E, Shelton JC, Bader DL, Lee DA. Differential regulation of gene expression in isolated tendon fascicles exposed to cyclic tensile strain in vitro. J Appl Physiol (1985). 2009 Feb; 106(2):506-12.
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