 Cell Adhesion Molecule-1
"Cell Adhesion Molecule-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.
| Descriptor ID |
D000075982
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| MeSH Number(s) |
D12.776.395.550.200.115 D12.776.543.550.200.128 D23.050.301.350.115
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| Concept/Terms |
Cell Adhesion Molecule-1- Cell Adhesion Molecule-1
- Adhesion Molecule-1, Cell
- Cell Adhesion Molecule 1
- Molecule-1, Cell Adhesion
- CADM1 Protein
- Tumor Suppressor in Lung Cancer 1 Protein
- IGSF4 Protein
- TSLC1 Protein
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Below are MeSH descriptors whose meaning is more general than "Cell Adhesion Molecule-1".
Below are MeSH descriptors whose meaning is more specific than "Cell Adhesion Molecule-1".
This graph shows the total number of publications written about "Cell Adhesion Molecule-1" by people in this website by year, and whether "Cell Adhesion Molecule-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cell Adhesion Molecule-1" by people in Profiles.
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Hartsough EJ, Weiss MB, Heilman SA, Purwin TJ, Kugel CH, Rosenbaum SR, Erkes DA, Tiago M, HooKim K, Chervoneva I, Aplin AE. CADM1 is a TWIST1-regulated suppressor of invasion and survival. Cell Death Dis. 2019 03 25; 10(4):281.
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Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, Szigeti-Buck K, Yi CX, Schriever SC, Tattikota SG, Carlo AS, Moroni M, Siemens J, Heuser A, van der Weyden L, Birkenfeld AL, Niendorf T, Poulet JFA, Horvath TL, Tsch?p MH, Heinig M, Trajkovski M, Haucke V, Poy MN. Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Nat Neurosci. 2017 Aug; 20(8):1096-1103.
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