Forkhead Box Protein L2
"Forkhead Box Protein L2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A forkhead box transcription factor that is expressed in the developing eyelid and during very early development of the gonad, prior to sex determination. It is essential for development of the ovary and inhibits SOX9 TRANSCRIPTION FACTOR to prevent differentiation to testes. It also induces APOPTOSIS in ovarian cells. Mutations in the FOXL2 gene are associated with BLEPHAROPHIMOSIS; Ptosis, and Epicanthus inversus (BPES with ovarian failure).
| Descriptor ID |
D000074842
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| MeSH Number(s) |
D12.776.260.950.249.032 D12.776.930.977.249.032
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Forkhead Box Protein L2".
Below are MeSH descriptors whose meaning is more specific than "Forkhead Box Protein L2".
This graph shows the total number of publications written about "Forkhead Box Protein L2" by people in this website by year, and whether "Forkhead Box Protein L2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Forkhead Box Protein L2" by people in Profiles.
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Ongaro L, Schang G, Zhou Z, Kumar TR, Treier M, Deng CX, Boehm U, Bernard DJ. Human Follicle-Stimulating Hormone ? Subunit Expression Depends on FOXL2 and SMAD4. Endocrinology. 2020 05 01; 161(5).
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Yu HC, Geiger EA, Medne L, Zackai EH, Shaikh TH. An individual with blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) and additional features expands the phenotype associated with mutations in KAT6B. Am J Med Genet A. 2014 Apr; 164A(4):950-7.