 Protein-Arginine Deiminases
"Protein-Arginine Deiminases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of ENZYMES that, in the presence of calcium ion, converts ARGININE to CITRULLINE in proteins.
| Descriptor ID |
D000076342
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| MeSH Number(s) |
D08.811.277.721
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| Concept/Terms |
Protein-Arginine Deiminases- Protein-Arginine Deiminases
- Deiminases, Protein-Arginine
- Protein Arginine Deiminases
- Protein-L-Arginine Iminohydrolase
- Iminohydrolase, Protein-L-Arginine
- Protein L Arginine Iminohydrolase
- Protein-Arginine Deiminase
- Deiminase, Protein-Arginine
- Protein Arginine Deiminase
- Peptidylarginine Deiminase
- Deiminase, Peptidylarginine
- Peptidylarginine Deiminases
- Deiminases, Peptidylarginine
- Protein-L-Arginine Iminohydrolases
- Iminohydrolases, Protein-L-Arginine
- Protein L Arginine Iminohydrolases
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Below are MeSH descriptors whose meaning is more general than "Protein-Arginine Deiminases".
Below are MeSH descriptors whose meaning is more specific than "Protein-Arginine Deiminases".
This graph shows the total number of publications written about "Protein-Arginine Deiminases" by people in this website by year, and whether "Protein-Arginine Deiminases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein-Arginine Deiminases" by people in Profiles.
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Demoruelle MK, Wang H, Davis RL, Visser A, Hoang J, Norris JM, Holers VM, Deane KD, Darrah E. Anti-peptidylarginine deiminase-4 antibodies at mucosal sites can activate peptidylarginine deiminase-4 enzyme activity in rheumatoid arthritis. Arthritis Res Ther. 2021 06 06; 23(1):163.
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Li G, Young CH, Snow B, Christensen AO, Demoruelle MK, Nemmara VV, Thompson PR, Rothfuss HM, Cherrington BD. Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome. Int J Mol Sci. 2020 Apr 10; 21(7).
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Malki L, Sarig O, Romano MT, M?chin MC, Peled A, Pavlovsky M, Warshauer E, Samuelov L, Uwakwe L, Briskin V, Mohamad J, Gat A, Isakov O, Rabinowitz T, Shomron N, Adir N, Simon M, McMichael A, Dlova NC, Betz RC, Sprecher E. Variant PADI3 in Central Centrifugal Cicatricial Alopecia. N Engl J Med. 2019 02 28; 380(9):833-841.
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Chang HH, Liu GY, Dwivedi N, Sun B, Okamoto Y, Kinslow JD, Deane KD, Demoruelle MK, Norris JM, Thompson PR, Sparks JA, Rao DA, Karlson EW, Hung HC, Holers VM, Ho IC. A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22. JCI Insight. 2016 Oct 20; 1(17):e90045.
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Willis VC, Gizinski AM, Banda NK, Causey CP, Knuckley B, Cordova KN, Luo Y, Levitt B, Glogowska M, Chandra P, Kulik L, Robinson WH, Arend WP, Thompson PR, Holers VM. N-a-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis. J Immunol. 2011 Apr 01; 186(7):4396-404.
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Kolfenbach JR, Deane KD, Derber LA, O'Donnell CI, Gilliland WR, Edison JD, Rosen A, Darrah E, Norris JM, Holers VM. Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis. Arthritis Rheum. 2010 Sep; 62(9):2633-9.
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Harris ML, Darrah E, Lam GK, Bartlett SJ, Giles JT, Grant AV, Gao P, Scott WW, El-Gabalawy H, Casciola-Rosen L, Barnes KC, Bathon JM, Rosen A. Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis. Arthritis Rheum. 2008 Jul; 58(7):1958-67.
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