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Kevin D Deane

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-7608

    Collapse Research 
    Collapse research activities and funding
    R56AI103023     (DEANE, KEVIN D)Aug 15, 2013 - Jul 31, 2014
    NIH
    The Role of the Lung in the Initiation of Rheumatoid Arthritis
    Role: Principal Investigator
    K23AR051461     (DEANE, KEVIN D)Sep 1, 2004 - Aug 31, 2010
    NIH
    Genetics, Exposures, and RA-Related Autoimmunity
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wilson TM, Bolt M, Stahly A, Lee JS, Bang TJ, Sachs PB, Deane KD, Humphries SM, Solomon JJ, Demoruelle MK. Transforming growth factor-beta is increased in sputum from individuals with rheumatoid arthritis-associated pulmonary fibrosis. Rheumatology (Oxford). 2025 Jun 01; 64(6):3989-3995. PMID: 39693122.
      View in: PubMed
    2. Atusingwize E, Deane K, Musoke D. Social determinants of malaria in low- and middle-income countries: a mixed-methods systematic review. Malar J. 2025 May 26; 24(1):165. PMID: 40420124.
      View in: PubMed
    3. van Steenbergen HW, Doornkamp F, Alivernini S, Backlund J, Codreanu C, Cohen SB, Combe B, Cope AP, Deane KD, England BR, Falahee M, de Jong PHP, Kleyer A, Lacaille D, Maat B, Mankia K, van Mulligen E, Nagy G, O'Neil LJ, Rodamaker L, Sahbudin I, van Schaardenburg D, Sepriano A, da Silva JAP, De Smet L, Sparks JA, Steyerberg EW, Studenic P, Wethington E, Landew? RL, Raza K, van der Helm-van Mil AHM. EULAR/American College of Rheumatology Risk Stratification Criteria for Development of Rheumatoid Arthritis in the Risk Stage of Arthralgia. Arthritis Rheumatol. 2025 May 08. PMID: 40343380.
      View in: PubMed
    4. Rachid Zaim S, Savage AK, Gillespie MA, Castillo JD, Bennett C, Torgerson TR, Becker LA, Mahler M, Moss L, Feser ML, Edison JD, Mikuls TR, Holers VM, Li XJ, Deane KD. Serum Proteomic Signatures Before the Diagnosis of Rheumatoid Arthritis: Evolving Biologic Pathways and Specific Periods of Disease Development. Arthritis Rheumatol. 2025 Apr 06. PMID: 40189919.
      View in: PubMed
    5. Wang W, Liu C, Firestein G, Skene P, Deane K, Holers M, Buckner J. Multi-lineage transcriptional and cell communication signatures define pathways in individuals at-risk for developing rheumatoid arthritis that initiate and perpetuate disease. Res Sq. 2025 Mar 31. PMID: 40235495.
      View in: PubMed
    6. Inamo J, Keegan J, Griffith A, Ghosh T, Horisberger A, Howard K, Pulford JF, Murzin E, Hancock B, Dominguez ST, Gurra MG, Gurajala S, Jonsson AH, Seifert JA, Feser ML, Norris JM, Cao Y, Apruzzese W, Bridges SL, Bykerk VP, Goodman S, Donlin LT, Firestein GS, Bathon JM, Hughes LB, Filer A, Pitzalis C, Anolik JH, Moreland L, Hacohen N, Guthridge JM, James JA, Cuda CM, Perlman H, Brenner MB, Raychaudhuri S, Sparks JA, Holers VM, Deane KD, Lederer J, Rao DA, Zhang F. Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis. J Clin Invest. 2025 Mar 17; 135(6). PMID: 40091833.
      View in: PubMed
    7. Liu C, Prideaux EB, Wu P, Boyle DL, Westermann A, Nguyen K, Tsaltskan V, Lazaro L, Ochoa A, Deane KD, Feser ML, Demoruelle MK, Kuhn KA, Holers VM, Zhang F, Moss LK, Criley M, Hattel B, Siedschlag M, Okada L, Gillespie MA, Genge P, Weiss M, Hernandez V, Reading J, Becker L, Buckner JH, Speake C, Bumol TF, Skene P, Firestein GS, Wang W. Multi-lineage transcriptional and cell communication signatures define pathways in individuals at-risk for developing rheumatoid arthritis that initiate and perpetuate disease. bioRxiv. 2025 Feb 09. PMID: 39974976.
      View in: PubMed
    8. Prideaux EB, Boyle DL, Choi E, Buckner JH, Robinson WH, Holers VM, Deane KD, Firestein GS, Wang W. Epigenetic trajectory predicts development of clinical rheumatoid arthritis in ACPA+ individuals: Targeting Immune Responses for Prevention of Rheumatoid Arthritis (TIP-RA). bioRxiv. 2025 Jan 29. PMID: 39463978.
      View in: PubMed
    9. McDermott GC, Gill R, Byrne S, Gagne S, Wang X, Paudel ML, Kowalski E, Qian G, Bade K, Mueller K, Saavedra A, Vanni KM, Getachew LS, Bolden C, O'Keeffe LA, Davis NA, Puri A, Mahajan T, Mulcaire-Jones E, Kortam N, Juge PA, Doyle TJ, Dellaripa PF, Wallace ZS, San Jose Estepar R, Washko GR, Bolster MB, Deane KD, Khanna D, England BR, Sparks JA. Risk factors for interstitial lung disease in early rheumatoid arthritis and external validation of screening strategies: Baseline results of SAIL-RA. medRxiv. 2025 Jan 27. PMID: 39974108.
      View in: PubMed
    10. Deane KD, Holers VM, Emery P, Mankia K, El-Gabalawy H, Sparks JA, Costenbader KH, Schett G, van der Helm-van Mil A, van Schaardenburg D, Thomas R, Cope AP. Therapeutic interception in individuals at risk of rheumatoid arthritis to prevent clinically impactful disease. Ann Rheum Dis. 2025 Jan; 84(1):14-28. PMID: 39874228.
      View in: PubMed
    11. Lamacchia C, Aymon R, Hattel BC, Aeby S, Kebbi-Beghdadi C, Gilbert B, Studer O, Norris JM, Nolers VM, Demoruelle MK, Feser ML, Moss LK, Courvoisier DS, Lauper K, Deane KD, Greub G, Finckh A. A potential role for chlamydial infection in rheumatoid arthritis development. Rheumatology (Oxford). 2025 01 01; 64(1):252-260. PMID: 38092030.
      View in: PubMed
    12. Deane KD, Donlin LT, Ritchlin CT, Kuhn KA. Are There Disease Endotypes in Axial Spondyloarthritis and How Would We Define Them? J Rheumatol. 2024 Dec 01; 51(12):1229-1234. PMID: 39448247.
      View in: PubMed
    13. He Z, Glass MC, Venkatesan P, Feser ML, Lazaro L, Okada LY, Tran NTT, He YD, Zaim SR, Bennett CE, Ravisankar P, Dornisch EM, Arishi NA, Asamoah AG, Barzideh S, Becker LA, Bemis EA, Buckner JH, Collora CE, Criley MAL, Demoruelle MK, Fleischer CL, Garber J, Genge PC, Gong Q, Graybuck LT, Gustafson CE, Hattel BC, Hernandez V, Heubeck AT, Kawelo EK, Krishnan U, Kuan EL, Kuhn KA, LaFrance CM, Lee KJ, Li R, Lord C, Mettey RR, Moss L, Musgrove B, Nguyen K, Ochoa A, Parthasarathy V, Pebworth MP, Pedrick C, Peng T, Phalen CG, Reading J, Roll CR, Seifert JA, Siedschlag MD, Speake C, Striebich CC, Stuckey TJ, Swanson EG, Takada H, Thai T, Thomson ZJ, Trieu N, Tsaltskan V, Wang W, Weiss MDA, Westermann A, Zhang F, Boyle DL, Goldrath AW, Bumol TF, Li XJ, Holers VM, Skene PJ, Savage AK, Firestein GS, Deane KD, Torgerson TR, Gillespie MA. Systemic inflammation and lymphocyte activation precede rheumatoid arthritis. bioRxiv. 2024 Nov 12. PMID: 39554042.
      View in: PubMed
    14. Deane KD. New insights into which ACPA-positive individuals will develop clinical rheumatoid arthritis. Rheumatology (Oxford). 2024 11 01; 63(11):2911-2913. PMID: 38837703.
      View in: PubMed
    15. Matson SM, Choi J, Rorah D, Khan S, Trofimoff A, Kim T, Lee DH, Abdolijomoor A, Chen M, Azeem I, Ngo L, Bang TJ, Sachs P, Deane KD, Demoruelle MK, Castro M, Lee JS. Airways Abnormalities in a Prospective Cohort of Patients With Rheumatoid Arthritis. Chest. 2025 Feb; 167(2):495-506. PMID: 39343293.
      View in: PubMed
    16. Deane KD, Holers VM, Emery P, Mankia K, El-Gabalawy H, Sparks JA, Costenbader KH, Schett G, van der Helm-van Mil A, van Schaardenburg D, Thomas R, Cope AP. Therapeutic interception in individuals at risk of rheumatoid arthritis to prevent clinically impactful disease. Ann Rheum Dis. 2024 Sep 24. PMID: 39242182.
      View in: PubMed
    17. Holers VM, Demoruelle KM, Buckner JH, James EA, Firestein GS, Robinson WH, Steere AC, Zhang F, Norris JM, Kuhn KA, Deane KD. Distinct mucosal endotypes as initiators and drivers of rheumatoid arthritis. Nat Rev Rheumatol. 2024 Oct; 20(10):601-613. PMID: 39251771.
      View in: PubMed
    18. Frost E, Hofmann JN, Huang WY, Frazer-Abel AA, Deane KD, Berndt SI. Serum levels of B-cell activating factor are associated with a reduced risk of chronic lymphocytic leukemia. Blood Cancer J. 2024 08 07; 14(1):132. PMID: 39112445.
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    19. Musoke D, Nalinya S, Lubega GB, Deane K, Ekirapa-Kiracho E, McCoy D. The impact of the COVID-19 lockdown on social and economic welfare in Uganda. Arch Public Health. 2024 Aug 06; 82(1):117. PMID: 39103969.
      View in: PubMed
    20. Nelson HA, Banerjee D, Novis CL, Deane KD, Feser ML, Nandakumar V. A comparison of anti-cyclic citrullinated peptides (CCP3 and CCP3.1) autoantibody tests in rheumatoid arthritis. Pract Lab Med. 2024 Aug; 41:e00420. PMID: 39161944.
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    21. Taruvinga T, Chingono RS, Olaru ID, Masiye K, Madanhire C, Munhenzva S, Sibanda S, Mafuva L, O'Sullivan N, Osman AY, Deane K, Brandson T, Munyanyi M, Makoni AC, Ngwenya S, Webb K, Chinyanga TT, Ferrand RA, Dixon J, Kranzer K, McCoy D. Understanding the impact of the COVID-19 pandemic and its control measures on women and children: A Zimbabwe case study. medRxiv. 2024 Jul 03. PMID: 38883725.
      View in: PubMed
    22. Goff SH, Bergstedt DT, Feser ML, Moss L, Mikuls TR, Edison JD, Holers VM, Martinez-Prat L, Aure MAR, Mahler M, Deane KD. Multi-Autoantibody Testing Identifies Expansion of Reactivity to Targeted Antigens Before a Diagnosis of Rheumatoid Arthritis. ACR Open Rheumatol. 2024 Sep; 6(9):587-597. PMID: 38950890.
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    23. Takada H, Demoruelle MK, Deane KD, Nakamura S, Katsumata Y, Ikari K, Buckner JH, Robinson WH, Seifert JA, Feser ML, Moss L, Norris JM, Harigai M, Hsieh EWY, Holers VM, Okamoto Y. Expansion of HLA-DR Positive Peripheral Helper T and Naive B Cells in Anticitrullinated Protein Antibody-Positive Individuals At Risk for Rheumatoid Arthritis. Arthritis Rheumatol. 2024 Jul; 76(7):1023-1035. PMID: 38412870.
      View in: PubMed
    24. O'Neil LJ, Alp?zar-Rodr?guez D, Deane KD. Rheumatoid Arthritis: The Continuum of Disease and Strategies for Prediction, Early Intervention, and Prevention. J Rheumatol. 2024 Apr 01; 51(4):337-349. PMID: 38224993.
      View in: PubMed
    25. Deane KD, Van Hoovels L, Joy VE, Olschowka N, Bossuyt X. From autoantibody test results to decision making: Incorporating likelihood ratios within medical practice. Autoimmun Rev. 2024 May; 23(5):103537. PMID: 38565401.
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    26. Deane KD. Rheumatoid arthritis: prediction of future clinically-apparent disease, and prevention. Curr Opin Rheumatol. 2024 05 01; 36(3):225-234. PMID: 38441488.
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    27. Baxter RM, Cabrera-Martinez B, Ghosh T, Rester C, Moreno MG, Borko TL, Selva S, Fleischer CL, Haakonsen N, Mayher A, Bowhay E, Evans C, Miller TM, Huey L, McWilliams J, van Bokhoven A, Deane KD, Knight V, Jordan KR, Ghosh D, Klarquist J, Kedl RM, Piquet AL, Hsieh EWY. SARS-CoV-2 Vaccine-Elicited Immunity after B Cell Depletion in Multiple Sclerosis. Immunohorizons. 2024 03 01; 8(3):254-268. PMID: 38483384.
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    28. Doyle TJ, Juge PA, Peljto AL, Lee S, Walts AD, Esposito AJ, Poli S, Gill R, Hatabu H, Nishino M, Dellaripa PF, Weinblatt ME, Shadick NA, Demoruelle MK, Sparks JA, Rosas IO, Granger B, Deane KD, Crestani B, Wolters PJ, Dieud? P, Lee JS. Short peripheral blood leukocyte telomere length in rheumatoid arthritis-interstitial lung disease. Thorax. 2024 01 18; 79(2):182-185. PMID: 38071573.
      View in: PubMed
    29. Musoke D, Deane K, Nalinya S, Lubega GB, Ekirapa-Kiracho E, McCoy D. The Unequal Economic and Livelihood Impacts of COVID-19 Lockdowns: Qualitative Evidence from Uganda. Inquiry. 2024 Jan-Dec; 61:469580241284281. PMID: 39305024.
      View in: PubMed
    30. James EA, Holers VM, Iyer R, Prideaux EB, Rao NL, Rims C, Muir VS, Posso SE, Bloom MS, Zia A, Elliott SE, Adamska JZ, Ai R, Brewer RC, Seifert JA, Moss L, Barzideh S, Demoruelle MK, Striebich CC, Okamoto Y, Sainbayar E, Crook AA, Peterson RA, Vanderlinden LA, Wang W, Boyle DL, Robinson WH, Buckner JH, Firestein GS, Deane KD. Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis. Nat Commun. 2023 11 22; 14(1):7637. PMID: 37993439.
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    31. Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, Kang JB, Rumker L, Mears J, Slowikowski K, Weinand K, Orange DE, Geraldino-Pardilla L, Deane KD, Tabechian D, Ceponis A, Firestein GS, Maybury M, Sahbudin I, Ben-Artzi A, Mandelin AM, Nerviani A, Lewis MJ, Rivellese F, Pitzalis C, Hughes LB, Horowitz D, DiCarlo E, Gravallese EM, Boyce BF, Moreland LW, Goodman SM, Perlman H, Holers VM, Liao KP, Filer A, Bykerk VP, Wei K, Rao DA, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes. Nature. 2023 Nov; 623(7987):616-624. PMID: 37938773.
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    32. Frost E, Hofmann JN, Huang WY, Parks CG, Frazer-Abel AA, Deane KD, Berndt SI. Antinuclear Antibodies Are Associated with an Increased Risk of Diffuse Large B-Cell Lymphoma. Cancers (Basel). 2023 Oct 31; 15(21). PMID: 37958403.
      View in: PubMed
    33. Parks CG, Wilson LE, Capello M, Deane KD, Hanash SM. Tumor-Associated and Systemic Autoimmunity in Pre-Clinical Breast Cancer among Post-Menopausal Women. Biomolecules. 2023 10 24; 13(11). PMID: 38002248.
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    34. Inamo J, Keegan J, Griffith A, Ghosh T, Horisberger A, Howard K, Pulford J, Murzin E, Hancock B, Jonsson AH, Seifert J, Feser ML, Norris JM, Cao Y, Apruzzese W, Louis Bridges S, Bykerk V, Goodman S, Donlin L, Firestein GS, Perlman H, Bathon JM, Hughes LB, Tabechian D, Filer A, Pitzalis C, Anolik JH, Moreland L, Guthridge JM, James JA, Brenner MB, Raychaudhuri S, Sparks JA, Michael Holers V, Deane KD, Lederer JA, Rao DA, Zhang F. Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis. bioRxiv. 2023 Jul 04. PMID: 37461737.
      View in: PubMed
    35. Moore RE, Wang T, Duvvuri B, Feser ML, Deane KD, Solomon JJ, Nelson JL, Demoruelle MK, Lood C. Prediction of Erosive Disease Development by Antimitochondrial Antibodies in Rheumatoid Arthritis. Arthritis Rheumatol. 2023 06; 75(6):890-899. PMID: 36580020.
      View in: PubMed
    36. Seifert JA, Bemis EA, Ramsden K, Lowell C, Polinski K, Feser M, Fleischer C, Demoruelle MK, Buckner J, Gregersen PK, Keating RM, Mikuls TR, O'Dell JR, Weisman MH, Deane KD, Norris JM, Steere AC, Holers VM. Association of Antibodies to Prevotella copri in Anti-Cyclic Citrullinated Peptide-Positive Individuals At Risk of Developing Rheumatoid Arthritis and in Patients With Early or Established Rheumatoid Arthritis. Arthritis Rheumatol. 2023 04; 75(4):507-516. PMID: 36259174.
      View in: PubMed
    37. Brewer RC, Lanz TV, Hale CR, Sepich-Poore GD, Martino C, Swafford AD, Carroll TS, Kongpachith S, Blum LK, Elliott SE, Blachere NE, Parveen S, Fak J, Yao V, Troyanskaya O, Frank MO, Bloom MS, Jahanbani S, Gomez AM, Iyer R, Ramadoss NS, Sharpe O, Chandrasekaran S, Kelmenson LB, Wang Q, Wong H, Torres HL, Wiesen M, Graves DT, Deane KD, Holers VM, Knight R, Darnell RB, Robinson WH, Orange DE. Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis. Sci Transl Med. 2023 02 22; 15(684):eabq8476. PMID: 36812347.
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    38. Lee JA, Mikuls TR, Deane KD, Sayles HR, Thiele GM, Edison JD, Wagner BD, Feser ML, Moss LK, Kelmenson LB, Robinson WH, Payne JB. Serum antibodies to periodontal pathogens prior to rheumatoid arthritis diagnosis: A case-control study. Semin Arthritis Rheum. 2023 04; 59:152176. PMID: 36812865.
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    39. Musoke D, Nalinya S, Lubega GB, Deane K, Ekirapa-Kiracho E, McCoy D. The effects of COVID-19 lockdown measures on health and healthcare services in Uganda. PLOS Glob Public Health. 2023; 3(1):e0001494. PMID: 36963035.
      View in: PubMed
    40. Moon JS, Younis S, Ramadoss NS, Iyer R, Sheth K, Sharpe O, Rao NL, Becart S, Carman JA, James EA, Buckner JH, Deane KD, Holers VM, Goodman SM, Donlin LT, Davis MM, Robinson WH. Cytotoxic CD8+ T cells target citrullinated antigens in rheumatoid arthritis. Nat Commun. 2023 01 19; 14(1):319. PMID: 36658110.
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    41. Chriswell ME, Lefferts AR, Clay MR, Hsu AR, Seifert J, Feser ML, Rims C, Bloom MS, Bemis EA, Liu S, Maerz MD, Frank DN, Demoruelle MK, Deane KD, James EA, Buckner JH, Robinson WH, Holers VM, Kuhn KA. Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum. Sci Transl Med. 2022 10 26; 14(668):eabn5166. PMID: 36288282.
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    42. Khassawneh B, Zhu C, Barkes B, Vestal B, Shrock S, Gillespie M, Pacheco K, Deane KD, Maier LA, Li QZ, Hamzeh N. Autoantibody profile in sarcoidosis, analysis from the GRADS sarcoidosis cohort. PLoS One. 2022; 17(10):e0274381. PMID: 36264970.
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    43. Deane KD. Targeting Environmental Risks to Prevent Rheumatic Disease. Rheum Dis Clin North Am. 2022 11; 48(4):931-943. PMID: 36333004.
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    44. Fleischer CL, Bemis EA, Feser ML, Kormendi VA, Zhang A, Ketcham K, White SD, Striebich CC, Deane KD, Harrison M. Preferences and Insights for Participation in a Rheumatoid Arthritis Clinical Prevention Trial: A Mixed-Methods Study. ACR Open Rheumatol. 2022 Nov; 4(11):974-982. PMID: 36112074.
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    45. Finckh A, Gilbert B, Hodkinson B, Bae SC, Thomas R, Deane KD, Alpizar-Rodriguez D, Lauper K. Global epidemiology of rheumatoid arthritis. Nat Rev Rheumatol. 2022 10; 18(10):591-602. PMID: 36068354.
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    46. Bergstedt DT, Tarter WJ, Peterson RA, Feser ML, Parish MC, Striebich CC, Demoruelle MK, Moss L, Bemis EA, Norris JM, Holers VM, Edison JD, Thiele GM, Mikuls TR, Deane KD. Antibodies to Citrullinated Protein Antigens, Rheumatoid Factor Isotypes and the Shared Epitope and the Near-Term Development of Clinically-Apparent Rheumatoid Arthritis. Front Immunol. 2022; 13:916277. PMID: 35812446.
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    47. Holers VM, Kuhn KA, Demoruelle MK, Norris JM, Firestein GS, James EA, Robinson WH, Buckner JH, Deane KD. Mechanism-driven strategies for prevention of rheumatoid arthritis. Rheumatol Autoimmun. 2022 Sep; 2(3):109-119. PMID: 36312783.
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    48. Vanderlinden LA, Bemis EA, Seifert J, Guthridge JM, Young KA, Demoruelle MK, Feser M, DeJager W, Macwana S, Mikuls TR, O'Dell JR, Weisman MH, Buckner J, Keating RM, Gaffney PM, Kelly JA, Langefeld CD, Deane KD, James JA, Holers VM, Norris JM. Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus. Front Immunol. 2022; 13:881332. PMID: 35720397.
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    49. Tsaltskan V, Nguyen K, Eaglin C, Holers VM, Deane KD, Firestein GS. Comparison of Web-Based Advertising and a Social Media Platform as Recruitment Tools for Underserved and Hard-to-Reach Populations in Rheumatology Clinical Research. ACR Open Rheumatol. 2022 Jul; 4(7):623-630. PMID: 35536990.
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    50. Purdue M, Zhang L, Vermeulen R, Smith MT, Hu W, Rhee J, Wen C, Huang Y, Tang X, Berndt SI, Frazer-Abel AA, Deane KD, Rothman N, Lan Q. Occupational trichloroethylene exposure and antinuclear antibodies: a cross-sectional study in China. Occup Environ Med. 2022 10; 79(10):717-720. PMID: 35504721.
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    51. Banda NK, Deane KD, Bemis EA, Strickland C, Seifert J, Jordan K, Goldman K, Morgan BP, Moreland LW, Lewis MJ, Pitzalis C, Holers VM. Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features. J Immunol. 2022 06 01; 208(11):2482-2496. PMID: 35500934.
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    52. Matson SM, Deane KD, Peljto AL, Bang TJ, Sachs PB, Walts AD, Collora C, Ye S, Demoruelle MK, Humphries SM, Schwartz DA, Lee JS. Prospective Identification of Subclinical Interstitial Lung Disease in a Rheumatoid Arthritis Cohort Is Associated with the MUC5B Promoter Variant. Am J Respir Crit Care Med. 2022 02 15; 205(4):473-476. PMID: 34874815.
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    53. Fechtner S, Berens H, Bemis E, Johnson RL, Guthridge CJ, Carlson NE, Demoruelle MK, Harley JB, Edison JD, Norris JA, Robinson WH, Deane KD, James JA, Holers VM. Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles. Arthritis Rheumatol. 2022 04; 74(4):597-603. PMID: 34605217.
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    54. Nalinya S, Musoke D, Deane K. Malaria prevention interventions beyond long-lasting insecticidal nets and indoor residual spraying in low- and middle-income countries: a scoping review. Malar J. 2022 Feb 02; 21(1):31. PMID: 35109848.
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    55. Haville S, Deane KD. Pre-RA: Can early diagnosis lead to prevention? Best Pract Res Clin Rheumatol. 2022 03; 36(1):101737. PMID: 34991984.
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    56. Okamoto Y, Devoe S, Seto N, Minarchick V, Wilson T, Rothfuss HM, Mohning MP, Arbet J, Kroehl M, Visser A, August J, Thomas SM, Charry LL, Fleischer C, Feser ML, Frazer-Abel AA, Norris JM, Cherrington BD, Janssen WJ, Kaplan MJ, Deane KD, Holers VM, Demoruelle MK. Association of Sputum Neutrophil Extracellular Trap Subsets With IgA Anti-Citrullinated Protein Antibodies in Subjects at Risk for Rheumatoid Arthritis. Arthritis Rheumatol. 2022 01; 74(1):38-48. PMID: 34369110.
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    57. Hughes-Austin JM, Ix JH, Ward SR, Weisman MH, ODell JR, Mikuls TR, Buckner JH, Gregersen PK, Keating RM, Demoruelle MK, Deane KD, Holers VM, Norris JM. Evaluating associations of joint swelling, joint stiffness and joint pain with physical activity in first-degree relatives of patients with rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA), a prospective cohort study. BMJ Open. 2021 09 14; 11(9):e050883. PMID: 34521672.
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    58. Mankia K, Siddle HJ, Kerschbaumer A, Alpizar Rodriguez D, Catrina AI, Ca?ete JD, Cope AP, Daien CI, Deane KD, El Gabalawy H, Finckh A, Holers VM, Koloumas M, Ometto F, Raza K, Zabalan C, van der Helm-van Mil A, van Schaardenburg D, Aletaha D, Emery P. EULAR points to consider for conducting clinical trials and observational studies in individuals at risk of rheumatoid arthritis. Ann Rheum Dis. 2021 10; 80(10):1286-1298. PMID: 34362746.
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    59. Bettner LF, Peterson RA, Bergstedt DT, Kelmenson LB, Demoruelle MK, Mikuls TR, Edison JD, Parish MC, Feser ML, Frazer-Abel AA, Moss LK, Mahler M, Holers VM, Deane KD. Combinations of Anticyclic Citrullinated Protein Antibody, Rheumatoid Factor, and Serum Calprotectin Positivity Are Associated With the Diagnosis of Rheumatoid Arthritis Within 3 Years. ACR Open Rheumatol. 2021 Oct; 3(10):684-689. PMID: 34288565.
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    60. Deane K, Wamoyi J, Mgunga S, Changalucha J. HIV testing attitudes and practices amongst 'wealthy men': qualitative evidence from Tanzania. Cult Health Sex. 2022 09; 24(9):1215-1229. PMID: 34254898.
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    61. O'Neil LJ, Deane KD. Striking a balance in rheumatoid arthritis prevention trials. Nat Rev Rheumatol. 2021 07; 17(7):385-386. PMID: 33963305.
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    62. Fraenkel L, Bathon JM, England BR, St Clair EW, Arayssi T, Carandang K, Deane KD, Genovese M, Huston KK, Kerr G, Kremer J, Nakamura MC, Russell LA, Singh JA, Smith BJ, Sparks JA, Venkatachalam S, Weinblatt ME, Al-Gibbawi M, Baker JF, Barbour KE, Barton JL, Cappelli L, Chamseddine F, George M, Johnson SR, Kahale L, Karam BS, Khamis AM, Navarro-Mill?n I, Mirza R, Schwab P, Singh N, Turgunbaev M, Turner AS, Yaacoub S, Akl EA. 2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis. Arthritis Rheumatol. 2021 07; 73(7):1108-1123. PMID: 34101376.
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    129. Sparks JA, Iversen MD, Miller Kroouze R, Mahmoud TG, Triedman NA, Kalia SS, Atkinson ML, Lu B, Deane KD, Costenbader KH, Green RC, Karlson EW. Personalized Risk Estimator for Rheumatoid Arthritis (PRE-RA) Family Study: rationale and design for a randomized controlled trial evaluating rheumatoid arthritis risk education to first-degree relatives. Contemp Clin Trials. 2014 Sep; 39(1):145-57. PMID: 25151341.
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    130. Deane KD. Preclinical rheumatoid arthritis (autoantibodies): an updated review. Curr Rheumatol Rep. 2014 May; 16(5):419. PMID: 24643396.
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    131. Kuller LH, Mackey RH, Walitt BT, Deane KD, Holers VM, Robinson WH, Sokolove J, Chang Y, Liu S, Parks CG, Wright NC, Moreland LW. Determinants of mortality among postmenopausal women in the women's health initiative who report rheumatoid arthritis. Arthritis Rheumatol. 2014 Mar; 66(3):497-507. PMID: 24574208.
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    132. Kuller LH, Mackey RH, Walitt BT, Deane KD, Holers VM, Robinson WH, Sokolove J, Chang Y, Moreland LW. Rheumatoid arthritis in the Women's Health Initiative: methods and baseline evaluation. Am J Epidemiol. 2014 Apr 01; 179(7):917-26. PMID: 24569640.
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    133. Deane KD, El-Gabalawy H. Pathogenesis and prevention of rheumatic disease: focus on preclinical RA and SLE. Nat Rev Rheumatol. 2014 Apr; 10(4):212-28. PMID: 24514912.
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    134. Demoruelle MK, Deane KD, Holers VM. When and where does inflammation begin in rheumatoid arthritis? Curr Opin Rheumatol. 2014 Jan; 26(1):64-71. PMID: 24247116.
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    135. Demoruelle MK, Solomon JJ, Fischer A, Deane KD. The lung may play a role in the pathogenesis of rheumatoid arthritis. Int J Clin Rheumtol. 2014; 9(3):295-309. PMID: 26089988.
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    136. Deane KD. Can rheumatoid arthritis be prevented? Best Pract Res Clin Rheumatol. 2013 Aug; 27(4):467-85. PMID: 24315049.
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    137. Willis VC, Demoruelle MK, Derber LA, Chartier-Logan CJ, Parish MC, Pedraza IF, Weisman MH, Norris JM, Holers VM, Deane KD. Sputum autoantibodies in patients with established rheumatoid arthritis and subjects at risk of future clinically apparent disease. Arthritis Rheum. 2013 Oct; 65(10):2545-54. PMID: 23817979.
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    138. Demoruelle MK, Parish MC, Derber LA, Kolfenbach JR, Hughes-Austin JM, Weisman MH, Gilliland W, Edison JD, Buckner JH, Mikuls TR, O'Dell JR, Keating RM, Gregersen PK, Norris JM, Holers VM, Deane KD. Performance of anti-cyclic citrullinated Peptide assays differs in subjects at increased risk of rheumatoid arthritis and subjects with established disease. Arthritis Rheum. 2013 Sep; 65(9):2243-52. PMID: 23686569.
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    139. Moreau KL, Deane KD, Meditz AL, Kohrt WM. Tumor necrosis factor-a inhibition improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women. Atherosclerosis. 2013 Oct; 230(2):390-6. PMID: 24075772.
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    140. Young KA, Deane KD, Derber LA, Hughes-Austin JM, Wagner CA, Sokolove J, Weisman MH, Buckner JH, Mikuls TR, O'Dell JR, Keating RM, Gregersen PK, Robinson WH, Holers VM, Norris JM. Relatives without rheumatoid arthritis show reactivity to anti-citrullinated protein/peptide antibodies that are associated with arthritis-related traits: studies of the etiology of rheumatoid arthritis. Arthritis Rheum. 2013 Aug; 65(8):1995-2004. PMID: 23754702.
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    141. Demoruelle MK, Deane KD. Reply: To PMID 22183986. Arthritis Rheum. 2013 Jun; 65(6):1673-4. PMID: 23436248.
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    142. Gan RW, Deane KD, Zerbe GO, Demoruelle MK, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Holers VM, Norris JM. Relationship between air pollution and positivity of RA-related autoantibodies in individuals without established RA: a report on SERA. Ann Rheum Dis. 2013 Dec; 72(12):2002-5. PMID: 23572338.
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    143. Deane KD, Nicolls MR. Developing better biomarkers for connective tissue disease-associated interstitial lung disease: citrullinated hsp90 autoantibodies in rheumatoid arthritis. Arthritis Rheum. 2013 Apr; 65(4):864-8. PMID: 23400799.
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    144. Walitt B, Mackey R, Kuller L, Deane KD, Robinson W, Holers VM, Chang YF, Moreland L. Predictive value of autoantibody testing for validating self-reported diagnoses of rheumatoid arthritis in the Women's Health Initiative. Am J Epidemiol. 2013 May 01; 177(9):887-93. PMID: 23492764.
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    145. Demoruelle MK, Kahr A, Verilhac K, Deane K, Fischer A, West S. Recent-onset systemic lupus erythematosus complicated by acute respiratory failure. Arthritis Care Res (Hoboken). 2013 Feb; 65(2):314-23. PMID: 22972558.
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    146. Mikuls TR, Thiele GM, Deane KD, Payne JB, O'Dell JR, Yu F, Sayles H, Weisman MH, Gregersen PK, Buckner JH, Keating RM, Derber LA, Robinson WH, Holers VM, Norris JM. Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis. Arthritis Rheum. 2012 Nov; 64(11):3522-30. PMID: 22736291.
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    147. Demoruelle MK, Deane KD. Treatment strategies in early rheumatoid arthritis and prevention of rheumatoid arthritis. Curr Rheumatol Rep. 2012 Oct; 14(5):472-80. PMID: 22773387.
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    148. Moreau KL, Hildreth KL, Meditz AL, Deane KD, Kohrt WM. Endothelial function is impaired across the stages of the menopause transition in healthy women. J Clin Endocrinol Metab. 2012 Dec; 97(12):4692-700. PMID: 22969140.
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    149. Hughes-Austin JM, Deane KD, Derber LA, Kolfenbach JR, Zerbe GO, Sokolove J, Lahey LJ, Weisman MH, Buckner JH, Mikuls TR, O'Dell JR, Keating RM, Gregersen PK, Robinson WH, Holers VM, Norris JM. Multiple cytokines and chemokines are associated with rheumatoid arthritis-related autoimmunity in first-degree relatives without rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA). Ann Rheum Dis. 2013 Jun; 72(6):901-7. PMID: 22915618.
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    150. Deane KD. Learning about the natural history of rheumatoid arthritis development through prospective study of subjects at high risk of rheumatoid arthritis-related autoimmunity. Arthritis Rheum. 2012 Jun; 64(6):1708-12. PMID: 22354795.
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    151. Karlson EW, Deane K. Environmental and gene-environment interactions and risk of rheumatoid arthritis. Rheum Dis Clin North Am. 2012 May; 38(2):405-26. PMID: 22819092.
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    152. Sokolove J, Bromberg R, Deane KD, Lahey LJ, Derber LA, Chandra PE, Edison JD, Gilliland WR, Tibshirani RJ, Norris JM, Holers VM, Robinson WH. Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis. PLoS One. 2012; 7(5):e35296. PMID: 22662108.
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    153. Fischer A, Solomon JJ, du Bois RM, Deane KD, Olson AL, Fernandez-Perez ER, Huie TJ, Stevens AD, Gill MB, Rabinovitch AM, Lynch DA, Burns DA, Pineiro IS, Groshong SD, Duarte Achcar RD, Brown KK, Martin RJ, Swigris JJ. Lung disease with anti-CCP antibodies but not rheumatoid arthritis or connective tissue disease. Respir Med. 2012 Jul; 106(7):1040-7. PMID: 22503074.
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    154. Moreau KL, Meditz A, Deane KD, Kohrt WM. Tetrahydrobiopterin improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women. Am J Physiol Heart Circ Physiol. 2012 Mar 01; 302(5):H1211-8. PMID: 22245769.
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    155. Demoruelle MK, Weisman MH, Simonian PL, Lynch DA, Sachs PB, Pedraza IF, Harrington AR, Kolfenbach JR, Striebich CC, Pham QN, Strickland CD, Petersen BD, Parish MC, Derber LA, Norris JM, Holers VM, Deane KD. Brief report: airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity? Arthritis Rheum. 2012 Jun; 64(6):1756-61. PMID: 22183986.
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    156. Demoruelle MK, Deane K. Antibodies to citrullinated protein antigens (ACPAs): clinical and pathophysiologic significance. Curr Rheumatol Rep. 2011 Oct; 13(5):421-30. PMID: 21713412.
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    157. Deane KD, Tyler KN, Johnson DW, Tanabe JL, Oskarrson BE, Nitka EE, Brass E, Davies JK, Striebich CC. Susac syndrome and pregnancy: disease management. J Clin Rheumatol. 2011 Mar; 17(2):83-8. PMID: 21325959.
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    158. Deane KD, O'Donnell CI, Hueber W, Majka DS, Lazar AA, Derber LA, Gilliland WR, Edison JD, Norris JM, Robinson WH, Holers VM. The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner. Arthritis Rheum. 2010 Nov; 62(11):3161-72. PMID: 20597112.
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    159. Deane KD, Parkhurst JO, Johnston D. Linking migration, mobility and HIV. Trop Med Int Health. 2010 Dec; 15(12):1458-63. PMID: 20958895.
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    160. Kolfenbach JR, Deane KD, Derber LA, O'Donnell CI, Gilliland WR, Edison JD, Rosen A, Darrah E, Norris JM, Holers VM. Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis. Arthritis Rheum. 2010 Sep; 62(9):2633-9. PMID: 20496417.
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    161. Ercan A, Cui J, Chatterton DE, Deane KD, Hazen MM, Brintnell W, O'Donnell CI, Derber LA, Weinblatt ME, Shadick NA, Bell DA, Cairns E, Solomon DH, Holers VM, Rudd PM, Lee DM. Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis. Arthritis Rheum. 2010 Aug; 62(8):2239-48. PMID: 20506563.
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    162. Deane KD, Norris JM, Holers VM. Preclinical rheumatoid arthritis: identification, evaluation, and future directions for investigation. Rheum Dis Clin North Am. 2010 May; 36(2):213-41. PMID: 20510231.
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    163. Kolfenbach JR, Deane KD, Derber LA, O'Donnell C, Weisman MH, Buckner JH, Gersuk VH, Wei S, Mikuls TR, O'Dell J, Gregersen PK, Keating RM, Norris JM, Holers VM. A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA. Arthritis Rheum. 2009 Dec 15; 61(12):1735-42. PMID: 19950324.
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    164. Deane KD, Striebich CC, Goldstein BL, Derber LA, Parish MC, Feser ML, Hamburger EM, Brake S, Belz C, Goddard J, Norris JM, Karlson EW, Holers VM. Identification of undiagnosed inflammatory arthritis in a community health fair screen. Arthritis Rheum. 2009 Dec 15; 61(12):1642-9. PMID: 19950306.
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    165. Feser M, Derber LA, Deane KD, Lezotte DC, Weisman MH, Buckner JH, Mikuls T, O'Dell J, Gregersen PK, Holers VM, Norris JM. Plasma 25,OH vitamin D concentrations are not associated with rheumatoid arthritis (RA)-related autoantibodies in individuals at elevated risk for RA. J Rheumatol. 2009 May; 36(5):943-6. PMID: 19286844.
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    166. Gizinski AM, Mascolo M, Loucks JL, Kervitsky A, Meehan RT, Brown KK, Holers VM, Deane KD. Rheumatoid arthritis (RA)-specific autoantibodies in patients with interstitial lung disease and absence of clinically apparent articular RA. Clin Rheumatol. 2009 May; 28(5):611-3. PMID: 19252818.
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    167. Majka DS, Deane KD, Parrish LA, Lazar AA, Bar?n AE, Walker CW, Rubertone MV, Gilliland WR, Norris JM, Holers VM. Duration of preclinical rheumatoid arthritis-related autoantibody positivity increases in subjects with older age at time of disease diagnosis. Ann Rheum Dis. 2008 Jun; 67(6):801-7. PMID: 17974596.
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    168. Young KA, Parrish LA, Zerbe GO, Rewers M, Deane KD, Michael Holers V, Norris JM. Perinatal and early childhood risk factors associated with rheumatoid factor positivity in a healthy paediatric population. Ann Rheum Dis. 2007 Feb; 66(2):179-83. PMID: 17242018.
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    169. Bhatia SS, Majka DS, Kittelson JM, Parrish LA, Ferucci ED, Deane KD, Arend WP, Rewers M, Michael Holers V, Norris JM. Rheumatoid factor seropositivity is inversely associated with oral contraceptive use in women without rheumatoid arthritis. Ann Rheum Dis. 2007 Feb; 66(2):267-9. PMID: 16868018.
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    170. Deane KD, West SG. Antiphospholipid antibodies as a cause of pulmonary capillaritis and diffuse alveolar hemorrhage: a case series and literature review. Semin Arthritis Rheum. 2005 Dec; 35(3):154-65. PMID: 16325656.
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    171. Ferucci ED, Majka DS, Parrish LA, Moroldo MB, Ryan M, Passo M, Thompson SD, Deane KD, Rewers M, Arend WP, Glass DN, Norris JM, Holers VM. Antibodies against cyclic citrullinated peptide are associated with HLA-DR4 in simplex and multiplex polyarticular-onset juvenile rheumatoid arthritis. Arthritis Rheum. 2005 Jan; 52(1):239-46. PMID: 15641089.
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    172. Deane K, Fitch M, Carman M. An innovative art therapy program for cancer patients. Can Oncol Nurs J. 2000; 10(4):147-51, 152-7. PMID: 11894321.
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