 Type VII Secretion Systems
"Type VII Secretion Systems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bacterial secretion systems found in bacteria that have a MYCOLIC ACID-containing outer membrane such as MYCOBACTERIACEAE; Corynebacteriaceae; and NOCARDIACEAE. These are also known as ESX secretion systems because the first to be discovered is involved in secreting major virulence factors EsxA and EsxB. There are several subtypes of T7SSs including ESX-1, ESX-2, ESX-3, ESX-4, and ESX-5 secretion systems. The subtypes share some core components including an inner membrane channel-forming ATPase complex, a membrane-anchored mycosin, and a second channel that spans the outer mycolic acid-containing membrane.
| Descriptor ID |
D000069377
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| MeSH Number(s) |
D05.500.890.500.992
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| Concept/Terms |
Type VII Secretion Systems- Type VII Secretion Systems
- ESX Secretion Systems
- Systems, ESX Secretion
- Secretion Systems, Type VII
- T7SS Secretion System
- Secretion System, T7SS
- System, T7SS Secretion
- Type 7 Secretion Systems
- Secretion Systems, Type 7
- Secretion Systems, ESX
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Below are MeSH descriptors whose meaning is more general than "Type VII Secretion Systems".
Below are MeSH descriptors whose meaning is more specific than "Type VII Secretion Systems".
This graph shows the total number of publications written about "Type VII Secretion Systems" by people in this website by year, and whether "Type VII Secretion Systems" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 1 | 1 | | 2021 | 1 | 1 | 2 | | 2022 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Type VII Secretion Systems" by people in Profiles.
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Spencer BL, Job AM, Robertson CM, Hameed ZA, Serchejian C, Wiafe-Kwakye CS, Mendon?a JC, Apolonio MA, Nagao PE, Neely MN, Korotkova N, Korotkov KV, Patras KA, Doran KS. Heterogeneity of the group B streptococcal type VII secretion system and influence on colonization of the female genital tract. Mol Microbiol. 2023 08; 120(2):258-275.
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Spencer BL, Doran KS. Evolving understanding of the type VII secretion system in Gram-positive bacteria. PLoS Pathog. 2022 07; 18(7):e1010680.
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Spencer BL, Tak U, Mendon?a JC, Nagao PE, Niederweis M, Doran KS. A type VII secretion system in Group B Streptococcus mediates cytotoxicity and virulence. PLoS Pathog. 2021 12; 17(12):e1010121.
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Pajuelo D, Tak U, Zhang L, Danilchanka O, Tischler AD, Niederweis M. Toxin secretion and trafficking by Mycobacterium tuberculosis. Nat Commun. 2021 11 15; 12(1):6592.
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Tak U, Dokland T, Niederweis M. Pore-forming Esx proteins mediate toxin secretion by Mycobacterium tuberculosis. Nat Commun. 2021 01 15; 12(1):394.
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Chatterjee A, Willett JLE, Dunny GM, Duerkop BA. Phage infection and sub-lethal antibiotic exposure mediate Enterococcus faecalis type VII secretion system dependent inhibition of bystander bacteria. PLoS Genet. 2021 01; 17(1):e1009204.
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Tiwari S, Dutt TS, Chen B, Chen M, Kim J, Dai AZ, Lukose R, Shanley C, Fox A, Karger BR, Porcelli SA, Chan J, Podell BK, Obregon-Henao A, Orme IM, Jacobs WR, Henao-Tamayo M. BCG-Prime and boost with Esx-5 secretion system deletion mutant leads to better protection against clinical strains of Mycobacterium tuberculosis. Vaccine. 2020 10 21; 38(45):7156-7165.
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Alhajjar N, Chatterjee A, Spencer BL, Burcham LR, Willett JLE, Dunny GM, Duerkop BA, Doran KS. Genome-Wide Mutagenesis Identifies Factors Involved in Enterococcus faecalis Vaginal Adherence and Persistence. Infect Immun. 2020 09 18; 88(10).
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