 Lymphocytic choriomeningitis virus
"Lymphocytic choriomeningitis virus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The type species of ARENAVIRUS, part of the Old World Arenaviruses (ARENAVIRUSES, OLD WORLD), producing a silent infection in house and laboratory mice. In humans, infection with LCMV can be inapparent, or can present with an influenza-like illness, a benign aseptic meningitis, or a severe meningoencephalomyelitis. The virus can also infect monkeys, dogs, field mice, guinea pigs, and hamsters, the latter an epidemiologically important host.
| Descriptor ID |
D008217
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| MeSH Number(s) |
B04.820.057.070.100.550
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lymphocytic choriomeningitis virus".
Below are MeSH descriptors whose meaning is more specific than "Lymphocytic choriomeningitis virus".
This graph shows the total number of publications written about "Lymphocytic choriomeningitis virus" by people in this website by year, and whether "Lymphocytic choriomeningitis virus" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2011 | 1 | 1 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 2 | 0 | 2 | | 2015 | 2 | 0 | 2 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 2 | 1 | 3 | | 2019 | 1 | 1 | 2 | | 2021 | 1 | 1 | 2 | | 2023 | 1 | 0 | 1 | | 2024 | 1 | 1 | 2 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lymphocytic choriomeningitis virus" by people in Profiles.
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D'Antonio MA, Ware BC, DiLisio JE, Michaels MJ, Turner JA, Habenicht LM, Davenport BJ, Morrison TE, Pelanda R, Gapin L, Torres RM. Lpar5 regulates the CD8 T-cell response to persistent virus infection by altering exhaustion programming, survival, and NK receptor expression. J Immunol. 2025 Nov 01; 214(11):3055-3068.
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Bullock CB, Wang L, Ware BC, Wagoner N, Ohara RA, Liu T-T, Desai P, Peters B, Murphy KM, Handley SA, Morrison TE, Diamond MS. Type I interferon signaling in dendritic cells limits direct antigen presentation and CD8+ T cell responses against an arthritogenic alphavirus. mBio. 2024 12 11; 15(12):e0293024.
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Bloomfield CL, Gong J, Droho S, Makinde HM, Gurra MG, Stumpf CH, Kharel A, Gadhvi G, Winter DR, Cui W, Cuda CM, Lavine JA. Retinal microglia express more MHC class I and promote greater T-cell-driven inflammation than brain microglia. Front Immunol. 2024; 15:1399989.
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Moon-Walker A, Zhang Z, Zyla DS, Buck TK, Li H, Diaz Avalos R, Schendel SL, Hastie KM, Crotty S, Saphire EO. Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus. Cell Chem Biol. 2023 04 20; 30(4):403-411.e4.
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Sircy LM, Harrison-Chau M, Novis CL, Baessler A, Nguyen J, Hale JS. Protein Immunization Induces Memory CD4+ T Cells That Lack Th Lineage Commitment. J Immunol. 2021 09 01; 207(5):1388-1400.
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Abdel-Hakeem MS, Manne S, Beltra JC, Stelekati E, Chen Z, Nzingha K, Ali MA, Johnson JL, Giles JR, Mathew D, Greenplate AR, Vahedi G, Wherry EJ. Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation. Nat Immunol. 2021 08; 22(8):1008-1019.
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Rome KS, Stein SJ, Kurachi M, Petrovic J, Schwartz GW, Mack EA, Uljon S, Wu WW, DeHart AG, McClory SE, Xu L, Gimotty PA, Blacklow SC, Faryabi RB, Wherry EJ, Jordan MS, Pear WS. Trib1 regulates T cell differentiation during chronic infection by restraining the effector program. J Exp Med. 2020 05 04; 217(5).
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Ziegler CM, Dang L, Eisenhauer P, Kelly JA, King BR, Klaus JP, Manuelyan I, Mattice EB, Shirley DJ, Weir ME, Bruce EA, Ballif BA, Botten J. NEDD4 family ubiquitin ligases associate with LCMV Z's PPXY domain and are required for virus budding, but not via direct ubiquitination of Z. PLoS Pathog. 2019 11; 15(11):e1008100.
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Davenport B, Eberlein J, Nguyen TT, Victorino F, Jhun K, Abuirqeba H, van der Heide V, Heeger P, Homann D. Aging boosts antiviral CD8+T cell memory through improved engagement of diversified recall response determinants. PLoS Pathog. 2019 11; 15(11):e1008144.
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Kim YJ, Cubitt B, Chen E, Hull MV, Chatterjee AK, Cai Y, Kuhn JH, de la Torre JC. The ReFRAME library as a comprehensive drug repurposing library to identify mammarenavirus inhibitors. Antiviral Res. 2019 09; 169:104558.
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