 Epithelial Sodium Channels
"Epithelial Sodium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sodium channels found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON; the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. They are AMILORIDE-sensitive and play a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE.
| Descriptor ID |
D053503
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| MeSH Number(s) |
D12.776.157.530.400.875.200 D12.776.543.550.450.875.200 D12.776.543.585.400.875.200
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| Concept/Terms |
Epithelial Sodium Channels- Epithelial Sodium Channels
- Sodium Channels, Epithelial
- Epithelial Amiloride-Sensitive Sodium Channel
- Epithelial Amiloride Sensitive Sodium Channel
- Epithelial Sodium Ion Channels
- ENaC (Epithelial Na+ Channel)
- Epithelial Sodium Channel
- Sodium Channel, Epithelial
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Below are MeSH descriptors whose meaning is more general than "Epithelial Sodium Channels".
Below are MeSH descriptors whose meaning is more specific than "Epithelial Sodium Channels".
This graph shows the total number of publications written about "Epithelial Sodium Channels" by people in this website by year, and whether "Epithelial Sodium Channels" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2016 | 0 | 2 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Epithelial Sodium Channels" by people in Profiles.
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Yadav S, Shaughnessy CA, Zeitlin PL, Bratcher PE. Downregulation of epithelial sodium channel (ENaC) activity in human airway epithelia after low temperature incubation. BMJ Open Respir Res. 2021 02; 8(1).
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Vandenbeuch A, Kinnamon SC. Is the Amiloride-Sensitive Na+ Channel in Taste Cells Really ENaC? Chem Senses. 2020 05 21; 45(4):233-234.
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Livraghi-Butrico A, Grubb BR, Wilkinson KJ, Volmer AS, Burns KA, Evans CM, O'Neal WK, Boucher RC. Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease. Mucosal Immunol. 2017 03; 10(2):395-407.
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Li D, Zou L, Feng Y, Xu G, Gong Y, Zhao G, Ouyang W, Thurman JM, Chao W. Complement Factor B Production in Renal Tubular Cells and Its Role in Sodium Transporter Expression During Polymicrobial Sepsis. Crit Care Med. 2016 May; 44(5):e289-99.
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Gupta MD, Girish MP, Sikdar S, Ahuja R, Shah D, Kumar R, Rain M, Nejatizadeh A, Tyagi S, Pasha Q. ?-T594M epithelial sodium channel gene polymorphism and essential hypertension in individuals of Indo-Aryan ancestry in Northern India. Indian Heart J. 2014 Jul-Aug; 66(4):397-400.
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Peters DM, Vad?sz I, Wujak L, Wygrecka M, Olschewski A, Becker C, Herold S, Papp R, Mayer K, Rummel S, Brandes RP, G?nther A, Waldegger S, Eickelberg O, Seeger W, Morty RE. TGF-? directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):E374-83.
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Furgeson SB, Linas S. Mechanisms of type I and type II pseudohypoaldosteronism. J Am Soc Nephrol. 2010 Nov; 21(11):1842-5.
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Schweiger B, Moriarty MW, Cadnapaphornchai MA. Case report: severe neonatal hyperkalemia due to pseudohypoaldosteronism type 1. Curr Opin Pediatr. 2009 Apr; 21(2):269-71.
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Poschet JF, Timmins GS, Taylor-Cousar JL, Ornatowski W, Fazio J, Perkett E, Wilson KR, Yu HD, de Jonge HR, Deretic V. Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis. Am J Physiol Lung Cell Mol Physiol. 2007 Sep; 293(3):L712-9.
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Doctor RB, Johnson S, Brodsky KS, Amura CR, Gattone V, Fitz JG. Regulated ion transport in mouse liver cyst epithelial cells. Biochim Biophys Acta. 2007 Mar; 1772(3):345-54.
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