Halothane
"Halothane" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
Descriptor ID |
D006221
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MeSH Number(s) |
D02.455.526.340
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Concept/Terms |
Halothane- Halothane
- 1,1,1-Trifluoro-2-Chloro-2-Bromoethane
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Below are MeSH descriptors whose meaning is more general than "Halothane".
Below are MeSH descriptors whose meaning is more specific than "Halothane".
This graph shows the total number of publications written about "Halothane" by people in this website by year, and whether "Halothane" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 | 2005 | 1 | 0 | 1 | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Halothane" by people in Profiles.
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Feng W, Lopez JR, Antrobus S, Zheng J, Uryash A, Dong Y, Beqollari D, Bannister RA, Hopkins PM, Beam KG, Allen PD, Pessah IN. Putative malignant hyperthermia mutation CaV1.1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance. J Biol Chem. 2023 08; 299(8):104992.
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Pidikiti R, Shamim M, Mallela KM, Reddy KS, Johansson JS. Expression and characterization of a four-alpha-helix bundle protein that binds the volatile general anesthetic halothane. Biomacromolecules. 2005 May-Jun; 6(3):1516-23.
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Galinkin JL, Davis PJ, McGowan FX, Lynn AM, Rabb MF, Yaster M, Henson LG, Blum R, Hechtman D, Maxwell L, Szmuk P, Orr R, Krane EJ, Edwards S, Kurth CD. A randomized multicenter study of remifentanil compared with halothane in neonates and infants undergoing pyloromyotomy. II. Perioperative breathing patterns in neonates and infants with pyloric stenosis. Anesth Analg. 2001 Dec; 93(6):1387-92, table of contents.
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Davis PJ, Galinkin J, McGowan FX, Lynn AM, Yaster M, Rabb MF, Krane EJ, Kurth CD, Blum RH, Maxwell L, Orr R, Szmuk P, Hechtman D, Edwards S, Henson LG. A randomized multicenter study of remifentanil compared with halothane in neonates and infants undergoing pyloromyotomy. I. Emergence and recovery profiles. Anesth Analg. 2001 Dec; 93(6):1380-6, table of contents.
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Avram MJ, Krejcie TC, Niemann CU, Klein C, Gentry WB, Shanks CA, Henthorn TK. The effect of halothane on the recirculatory pharmacokinetics of physiologic markers. Anesthesiology. 1997 Dec; 87(6):1381-93.
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Levine MF, Sarner J, Lerman J, Davis P, Sikich N, Maloney K, Motoyama E, Cook DR. Plasma inorganic fluoride concentrations after sevoflurane anesthesia in children. Anesthesiology. 1996 Feb; 84(2):348-53.
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Lockwood LL, Silbert LH, Laudenslager ML, Watkins LR, Maier SF. Anesthesia-induced modulation of in vivo antibody levels: a study of pentobarbital, chloral hydrate, methoxyflurane, halothane, and ketamine/xylazine. Anesth Analg. 1993 Oct; 77(4):769-74.
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Morrison JE, Matthews D, Washington R, Fennessey PV, Harrison LM. Phenol motor point blocks in children: plasma concentrations and cardiac dysrhythmias. Anesthesiology. 1991 Aug; 75(2):359-62.
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Yaster M. Does halothane protect against hypoxia? Anesthesiology. 1988 Feb; 68(2):318-9.
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Satoh H, Gillette JR, Davies HW, Schulick RD, Pohl LR. Immunochemical evidence of trifluoroacetylated cytochrome P-450 in the liver of halothane-treated rats. Mol Pharmacol. 1985 Nov; 28(5):468-74.
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