 Eicosapentaenoic Acid
"Eicosapentaenoic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
| Descriptor ID |
D015118
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| MeSH Number(s) |
D10.212.302.380.410.385 D10.251.355.255.200 D10.251.355.337.290 D10.627.430.450.390
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| Concept/Terms |
Eicosapentaenoic Acid- Eicosapentaenoic Acid
- Eicosapentanoic Acid
- Acid, Eicosapentanoic
- omega-3-Eicosapentaenoic Acid
- omega 3 Eicosapentaenoic Acid
- Timnodonic Acid
- 5,8,11,14,17-Eicosapentaenoic Acid
- 5,8,11,14,17-Icosapentaenoic Acid
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Below are MeSH descriptors whose meaning is more general than "Eicosapentaenoic Acid".
Below are MeSH descriptors whose meaning is more specific than "Eicosapentaenoic Acid".
This graph shows the total number of publications written about "Eicosapentaenoic Acid" by people in this website by year, and whether "Eicosapentaenoic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 4 | 0 | 4 | | 2011 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 | | 2017 | 0 | 1 | 1 | | 2019 | 1 | 1 | 2 | | 2020 | 4 | 1 | 5 | | 2021 | 2 | 1 | 3 | | 2022 | 1 | 0 | 1 | | 2023 | 0 | 2 | 2 | | 2024 | 2 | 0 | 2 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Eicosapentaenoic Acid" by people in Profiles.
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Grabert J, Mohsen G, Diepenseifen C, Heister U, Breil M, Rohner M, Graeff I, Kappler J, Gutbrod K, Dörmann P, Schewe JC, Kunsorg A, Mayr A, Stroemer A, Stoppe C, Zimmer S, Hoffmann U, Duerr GD, Wittmann M, Velten M. The impact of preexisting omega-3 fatty acid serum levels on outcomes following out-of-hospital cardiac arrest: A comprehensive investigation. Life Sci. 2025 Sep 15; 377:123770.
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Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, Dunbar RL, Ketchum SB, Tardif JC, Martens FMAC, Ballantyne CM, Szarek M, Mason RP. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025 Mar 04; 14(5):e038656.
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Lovins HB, Mehta A, Leuenberger LA, Yaeger MJ, Schott E, Hutton G, Manke J, Armstrong M, Reisdorph N, Tighe RM, Cochran SJ, Shaikh SR, Gowdy KM. Dietary Eicosapentaenoic Acid Improves Ozone-Induced Pulmonary Inflammation in C57BL/6 Mice. J Nutr. 2025 Feb; 155(2):465-475.
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Szarek M, Bhatt DL, Miller M, Brinton EA, Jacobson TA, Tardif JC, Ballantyne CM, Mason RP, Ketchum SB, Lira Pineda A, Doyle RT, Steg PG. Lipoprotein(a) Blood Levels and Cardiovascular Risk Reduction With Icosapent Ethyl. J Am Coll Cardiol. 2024 Apr 23; 83(16):1529-1539.
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Weintraub WS, Bhatt DL, Zhang Z, Dolman S, Boden WE, Bress AP, Bellows BK, Derington CG, Philip S, Steg G, Miller M, Brinton EA, Jacobson TA, Tardif JC, Ballantyne CM, Kolm P. Cost-Effectiveness of Icosapent Ethyl in REDUCE-IT USA: Results From Patients Randomized in the United States. J Am Heart Assoc. 2024 01 02; 13(1):e032413.
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Kim JS, Ma SF, Ma JZ, Huang Y, Bonham CA, Oldham JM, Adegunsoye A, Strek ME, Flaherty KR, Strickland E, Udofia I, Mooney JJ, Ghosh S, Maddipati K, Noth I. Associations of Plasma Omega-3 Fatty Acids With Progression and Survival in Pulmonary Fibrosis. Chest. 2024 03; 165(3):621-631.
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Weintraub WS, Bhatt DL, Zhang Z, Dolman S, Boden WE, Bress AP, King JB, Bellows BK, Tajeu GS, Derington CG, Johnson J, Andrade K, Steg PG, Miller M, Brinton EA, Jacobson TA, Tardif JC, Ballantyne CM, Kolm P. Cost-effectiveness of Icosapent Ethyl for High-risk Patients With Hypertriglyceridemia Despite Statin Treatment. JAMA Netw Open. 2022 02 01; 5(2):e2148172.
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Vander Ploeg M, Quinn K, Armstrong M, Manke J, Reisdorph N, Shaikh SR. SPM pathway marker analysis of the brains of obese mice in the absence and presence of eicosapentaenoic acid ethyl esters. Prostaglandins Leukot Essent Fatty Acids. 2021 12; 175:102360.
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Pal A, Sun S, Armstrong M, Manke J, Reisdorph N, Adams VR, Kennedy A, Zu Y, Moustaid-Moussa N, Carroll I, Shaikh SR. Beneficial effects of eicosapentaenoic acid on the metabolic profile of obese female mice entails upregulation of HEPEs and increased abundance of enteric Akkermansia muciniphila. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 01; 1867(1):159059.
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Zec MM, Krga I, Stojkovic L, ?ivkovic M, Pokimica B, Stankovic A, Glibetic M. Is There a FADS2-Modulated Link between Long-Chain Polyunsaturated Fatty Acids in Plasma Phospholipids and Polyphenol Intake in Adult Subjects Who Are Overweight? Nutrients. 2021 Jan 21; 13(2).
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