 Receptor, Serotonin, 5-HT2A
"Receptor, Serotonin, 5-HT2A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that contain SMOOTH MUSCLE. Selective 5-HT2A receptor antagonists include KETANSERIN. The 5-HT2A subtype is also located in BASAL GANGLIA and CEREBRAL CORTEX of the BRAIN where it mediates the effects of HALLUCINOGENS such as LSD.
| Descriptor ID |
D044402
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| MeSH Number(s) |
D12.776.543.750.670.800.200.100 D12.776.543.750.695.800.200.100 D12.776.543.750.720.850.200.100
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| Concept/Terms |
Receptor, Serotonin, 5-HT2A- Receptor, Serotonin, 5-HT2A
- 5-HT2A Receptor
- 5 HT2A Receptor
- Receptor, 5-HT2A
- Serotonin 2A Receptors
- Receptors, Serotonin 2A
- Serotonin 2A Receptor
- 5-HT(2A) Receptor
- Receptor, Serotonin 2A
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Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT2A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.670.800.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.670.800.200.100]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Serotonin [D12.776.543.750.695.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.695.800.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.695.800.200.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.720.850.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.720.850.200.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT2A".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT2A" by people in this website by year, and whether "Receptor, Serotonin, 5-HT2A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2013 | 2 | 1 | 3 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptor, Serotonin, 5-HT2A" by people in Profiles.
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Iguchi N, Carrasco A, Xie AX, Pineda RH, Malykhina AP, Wilcox DT. Functional constipation induces bladder overactivity associated with upregulations of Htr2 and Trpv2 pathways. Sci Rep. 2021 01 13; 11(1):1149.
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Davizon-Castillo P, Allawzi A, Sorrells M, Fisher S, Baltrunaite K, Neeves K, Nozik-Grayck E, DiPaola J, Delaney C. Platelet activation in experimental murine neonatal pulmonary hypertension. Physiol Rep. 2020 03; 8(5):e14386.
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Sapkota Y, Turcotte LM, Ehrhardt MJ, Howell RM, Arnold MA, Wilson CL, Leisenring W, Wang Z, Sampson J, Dagnall CL, Karlins E, Li SA, Hicks BD, Weathers R, Smith SA, Shelton K, Liu Q, Tucker MA, Chanock SJ, Zhang J, Hudson MM, Neglia JP, Armstrong GT, Robison LL, Morton LM, Bhatia S, Yasui Y. Genome-Wide Association Study in Irradiated Childhood Cancer Survivors Identifies HTR2A for?Subsequent Basal Cell Carcinoma. J Invest Dermatol. 2019 09; 139(9):2042-2045.e8.
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Delaney C, Sherlock L, Fisher S, Maltzahn J, Wright C, Nozik-Grayck E. Serotonin 2A receptor inhibition protects against the development of pulmonary hypertension and pulmonary vascular remodeling in neonatal mice. Am J Physiol Lung Cell Mol Physiol. 2018 05 01; 314(5):L871-L881.
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Parade SH, Novick AM, Parent J, Seifer R, Klaver SJ, Marsit CJ, Gobin AP, Yang BZ, Tyrka AR. Stress exposure and psychopathology alter methylation of the serotonin receptor 2A (HTR2A) gene in preschoolers. Dev Psychopathol. 2017 12; 29(5):1619-1626.
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de Bortoli VC, Yamashita PS, Zangrossi H. 5-HT1A and 5-HT2A receptor control of a panic-like defensive response in the rat dorsomedial hypothalamic nucleus. J Psychopharmacol. 2013 Dec; 27(12):1116-23.
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Delaney C, Gien J, Roe G, Isenberg N, Kailey J, Abman SH. Serotonin contributes to high pulmonary vascular tone in a sheep model of persistent pulmonary hypertension of the newborn. Am J Physiol Lung Cell Mol Physiol. 2013 Jun 15; 304(12):L894-901.
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Edelmann MN, Demers CH, Auger AP. Maternal touch moderates sex differences in juvenile social play behavior. PLoS One. 2013; 8(2):e57396.
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Tye H, Mueller SG, Prestle J, Scheuerer S, Schindler M, Nosse B, Prevost N, Brown CJ, Heifetz A, Moeller C, Pedret-Dunn A, Whittaker M. Novel 6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene analogues as potent and selective 5-HT(2C) agonists for the treatment of metabolic disorders. Bioorg Med Chem Lett. 2011 Jan 01; 21(1):34-7.
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K?nigshoff M, Dumitrascu R, Udalov S, Amarie OV, Reiter R, Grimminger F, Seeger W, Schermuly RT, Eickelberg O. Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention. Thorax. 2010 Nov; 65(11):949-55.
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