 GTP-Binding Protein alpha Subunit, Gi2
"GTP-Binding Protein alpha Subunit, Gi2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A PERTUSSIS TOXIN-sensitive GTP-binding protein alpha subunit. It couples with a variety of CELL SURFACE RECEPTORS, has been implicated in INTERLEUKIN-12 production, and may play a role in INFLAMMATORY BOWEL DISEASES.
| Descriptor ID |
D051960
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| MeSH Number(s) |
D08.811.277.040.330.300.200.100.200.500 D12.644.360.360.100.200.500 D12.776.157.325.332.100.200.500 D12.776.476.375.100.200.500 D12.776.543.325.100.200.500
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| Concept/Terms |
GTP-Binding Protein alpha Subunit, Gi2- GTP-Binding Protein alpha Subunit, Gi2
- GTP Binding Protein alpha Subunit, Gi2
- Galphai2 Protein
- Gi2-alpha Protein
- Gi2 alpha Protein
- G Protein Subunit alpha I2
- Galpha(i2) Protein
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunit, Gi2".
- Chemicals and Drugs [D]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Hydrolases [D08.811.277]
- Acid Anhydride Hydrolases [D08.811.277.040]
- GTP Phosphohydrolases [D08.811.277.040.330]
- GTP-Binding Proteins [D08.811.277.040.330.300]
- Heterotrimeric GTP-Binding Proteins [D08.811.277.040.330.300.200]
- GTP-Binding Protein alpha Subunits [D08.811.277.040.330.300.200.100]
- GTP-Binding Protein alpha Subunits, Gi-Go [D08.811.277.040.330.300.200.100.200]
- GTP-Binding Protein alpha Subunit, Gi2 [D08.811.277.040.330.300.200.100.200.500]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Intracellular Signaling Peptides and Proteins [D12.644.360]
- Heterotrimeric GTP-Binding Proteins [D12.644.360.360]
- GTP-Binding Protein alpha Subunits [D12.644.360.360.100]
- GTP-Binding Protein alpha Subunits, Gi-Go [D12.644.360.360.100.200]
- GTP-Binding Protein alpha Subunit, Gi2 [D12.644.360.360.100.200.500]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- GTP-Binding Proteins [D12.776.157.325]
- Heterotrimeric GTP-Binding Proteins [D12.776.157.325.332]
- GTP-Binding Protein alpha Subunits [D12.776.157.325.332.100]
- GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.157.325.332.100.200]
- GTP-Binding Protein alpha Subunit, Gi2 [D12.776.157.325.332.100.200.500]
- Intracellular Signaling Peptides and Proteins [D12.776.476]
- Heterotrimeric GTP-Binding Proteins [D12.776.476.375]
- GTP-Binding Protein alpha Subunits [D12.776.476.375.100]
- GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.476.375.100.200]
- GTP-Binding Protein alpha Subunit, Gi2 [D12.776.476.375.100.200.500]
- Membrane Proteins [D12.776.543]
- Heterotrimeric GTP-Binding Proteins [D12.776.543.325]
- GTP-Binding Protein alpha Subunits [D12.776.543.325.100]
- GTP-Binding Protein alpha Subunits, Gi-Go [D12.776.543.325.100.200]
- GTP-Binding Protein alpha Subunit, Gi2 [D12.776.543.325.100.200.500]
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunit, Gi2".
This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunit, Gi2" by people in this website by year, and whether "GTP-Binding Protein alpha Subunit, Gi2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "GTP-Binding Protein alpha Subunit, Gi2" by people in Profiles.
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Villanueva H, Visbal AP, Obeid NF, Ta AQ, Faruki AA, Wu MF, Hilsenbeck SG, Shaw CA, Yu P, Plummer NW, Birnbaumer L, Lewis MT. An essential role for Ga(i2) in Smoothened-stimulated epithelial cell proliferation in the mammary gland. Sci Signal. 2015 Sep 15; 8(394):ra92.
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Kremer KN, Kumar A, Hedin KE. G alpha i2 and ZAP-70 mediate RasGRP1 membrane localization and activation of SDF-1-induced T cell functions. J Immunol. 2011 Sep 15; 187(6):3177-85.
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Sun L, Peng Y, Sharrow AC, Iqbal J, Zhang Z, Papachristou DJ, Zaidi S, Zhu LL, Yaroslavskiy BB, Zhou H, Zallone A, Sairam MR, Kumar TR, Bo W, Braun J, Cardoso-Landa L, Schaffler MB, Moonga BS, Blair HC, Zaidi M. FSH directly regulates bone mass. Cell. 2006 Apr 21; 125(2):247-60.
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Short M, Nemenoff RA, Zawada WM, Stenmark KR, Das M. Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts. Am J Physiol Cell Physiol. 2004 Feb; 286(2):C416-25.
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