 JC Virus
"JC Virus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A species of POLYOMAVIRUS, originally isolated from the brain of a patient with progressive multifocal leukoencephalopathy. The patient's initials J.C. gave the virus its name. Infection is not accompanied by any apparent illness but serious demyelinating disease can appear later, probably following reactivation of latent virus.
| Descriptor ID |
D007577
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| MeSH Number(s) |
B04.280.210.620.615.400 B04.613.204.670.615.400
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| Concept/Terms |
JC Virus- JC Virus
- Polyomavirus, JC
- JC polyomavirus
- Polyomavirus hominis 2
- John Cunningham Virus
- Virus, John Cunningham
- Human Polyomavirus JC
- Polyomavirus JC, Human
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Below are MeSH descriptors whose meaning is more general than "JC Virus".
Below are MeSH descriptors whose meaning is more specific than "JC Virus".
This graph shows the total number of publications written about "JC Virus" by people in this website by year, and whether "JC Virus" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 3 | 0 | 3 | | 2009 | 1 | 2 | 3 | | 2010 | 0 | 1 | 1 | | 2011 | 2 | 2 | 4 | | 2013 | 2 | 2 | 4 | | 2015 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "JC Virus" by people in Profiles.
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Rempe T, Wang Q, Wu Q, Ballur Narayana Reddy V, Newcomer Z, Miravalle A, Mao-Draayer Y. Progressive multifocal leukoencephalopathy and granule cell neuronopathy with novel mutation flanking VP1 C-terminus in natalizumab-extended interval dosing. Neurol Neuroimmunol Neuroinflamm. 2020 05 04; 7(3).
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Erickson KD, Garcea RL. Viral replication centers and the DNA damage response in JC virus-infected cells. Virology. 2019 02; 528:198-206.
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Ramanan P, Timmerman EA, Fidler ME, Amer H, Pritt BS, Schwab DA, Batterman HJ, Binnicker MJ. A kidney transplant recipient with renal medullary viral cytopathic changes. Transpl Infect Dis. 2017 Feb; 19(1).
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Zerbe CS, Marciano BE, Katial RK, Santos CB, Adamo N, Hsu AP, Hanks ME, Darnell DN, Quezado MM, Frein C, Barnhart LA, Anderson VL, Uzel G, Freeman AF, Lisco A, Nath A, Major EO, Sampaio EP, Holland SM. Progressive Multifocal Leukoencephalopathy in Primary Immune Deficiencies: Stat1 Gain of Function and Review of the Literature. Clin Infect Dis. 2016 Apr 15; 62(8):986-94.
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Patera AC, Butler SL, Cinque P, Clifford DB, Elston R, Garcea RL, Major EO, Pavlovic D, Peterson IS, Ryan AM, Tyler KL, Weber T. 2nd International Conference on Progressive Multifocal Leukoencephalopathy (PML) 2015: JCV virology, progressive multifocal leukoencephalopathy pathogenesis, diagnosis and risk stratification, and new approaches to prevention and treatment. J Neurovirol. 2015 Dec; 21(6):702-5.
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Scott FI, Osterman MT. Natalizumab for Crohn's Disease: Down but Not Out. Clin Gastroenterol Hepatol. 2015 Nov; 13(11):1926-8.
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Sadeghi F, Salehi-Vaziri M, Ghodsi SM, Alizadeh A, Bokharaei-Salim F, Saroukalaei ST, Mirbolouk M, Monavari SH, Keyvani H. Prevalence of JC polyomavirus large T antigen sequences among Iranian patients with central nervous system tumors. Arch Virol. 2015 Jan; 160(1):61-8.
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Sospedra M, Schippling S, Yousef S, Jelcic I, Bofill-Mas S, Planas R, Stellmann JP, Demina V, Cinque P, Garcea R, Croughs T, Girones R, Martin R. Treating progressive multifocal leukoencephalopathy with interleukin 7 and vaccination with JC virus capsid protein VP1. Clin Infect Dis. 2014 Dec 01; 59(11):1588-92.
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Chen CJ, Burke JM, Kincaid RP, Azarm KD, Mireles N, Butel JS, Sullivan CS. Naturally arising strains of polyomaviruses with severely attenuated microRNA expression. J Virol. 2014 Nov; 88(21):12683-93.
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Scott FI, Osterman MT, McConnell RA, Lorusso M, Aberra F, Kerner C, Lichtenstein GR, Lewis JD. Impact of JC virus antibody testing in patients with Crohn's disease with loss of response to infliximab: a Markov model. Inflamm Bowel Dis. 2013 Nov; 19(12):2625-33.
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