 Stavudine
"Stavudine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
| Descriptor ID |
D018119
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| MeSH Number(s) |
D03.383.742.680.705.875 D13.570.230.500.850 D13.570.230.855.875 D13.570.685.705.875
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| Concept/Terms |
Stavudine- Stavudine
- D4T
- 2',3'-Didehydro-3'-deoxythymidine
- 2',3' Didehydro 3' deoxythymidine
- 2',3'-Didehydro-2',3'-dideoxythmidine
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Below are MeSH descriptors whose meaning is more general than "Stavudine".
Below are MeSH descriptors whose meaning is more specific than "Stavudine".
This graph shows the total number of publications written about "Stavudine" by people in this website by year, and whether "Stavudine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Stavudine" by people in Profiles.
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Innes S, van der Laan L, Anderson PL, Cotton M, Denti P. Can We Improve Stavudine's Safety Profile in Children? Pharmacokinetics of Intracellular Stavudine Triphosphate with Reduced Dosing. Antimicrob Agents Chemother. 2018 11; 62(11).
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Nelson BC, Borok MZ, Mhlanga TO, Makadzange AT, Campbell TB. AIDS-associated Kaposi sarcoma: outcomes after initiation of antiretroviral therapy at a university-affiliated hospital in urban Zimbabwe. Int J Infect Dis. 2013 Oct; 17(10):e902-6.
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Azzoni L, Foulkes AS, Firnhaber C, Yin X, Xiang ZQ, Li Y, Stevens W, Gross R, Ertl HC, Sanne I, Montaner LJ. Antiretroviral therapy interruptions result in loss of protective humoral immunity to neoantigens in HIV-infected individuals. AIDS. 2012 Jul 17; 26(11):1355-62.
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Firnhaber C, Azzoni L, Foulkes AS, Gross R, Yin X, Van Amsterdam D, Schulze D, Glencross DK, Stevens W, Hunt G, Morris L, Fox L, Sanne I, Montaner LJ. Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection. PLoS One. 2011; 6(6):e21450.
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Shlay JC, Sharma S, Peng G, Gibert CL, Grunfeld C. Long-term subcutaneous tissue changes among antiretroviral-naive persons initiating stavudine, zidovudine, or abacavir with lamivudine. J Acquir Immune Defic Syndr. 2008 May 01; 48(1):53-62.
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Shlay JC, Visnegarwala F, Bartsch G, Wang J, Peng G, El-Sadr WM, Gibert C, Kotler D, Grunfeld C, Raghavan S. Body composition and metabolic changes in antiretroviral-naive patients randomized to didanosine and stavudine vs. abacavir and lamivudine. J Acquir Immune Defic Syndr. 2005 Feb 01; 38(2):147-55.
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Velsor LW, Kovacevic M, Goldstein M, Leitner HM, Lewis W, Day BJ. Mitochondrial oxidative stress in human hepatoma cells exposed to stavudine. Toxicol Appl Pharmacol. 2004 Aug 15; 199(1):10-9.
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Wittenstein B, Rogers V, Novelli V, Clayton PT, Kenny MB, Peters MJ. "African medicine" and Reye's syndrome. Lancet. 2004 Mar 13; 363(9412):860.
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Simpson DM, Tagliati M. Nucleoside analogue-associated peripheral neuropathy in human immunodeficiency virus infection. J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 01; 9(2):153-61.
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