 G Protein-Coupled Inwardly-Rectifying Potassium Channels
"G Protein-Coupled Inwardly-Rectifying Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of inwardly-rectifying potassium channels that are activated by PERTUSSIS TOXIN sensitive G-PROTEIN-COUPLED RECEPTORS. GIRK potassium channels are primarily activated by the complex of GTP-BINDING PROTEIN BETA SUBUNITS and GTP-BINDING PROTEIN GAMMA SUBUNITS.
| Descriptor ID |
D051676
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| MeSH Number(s) |
D12.776.157.530.400.600.450.500 D12.776.543.550.450.750.450.500 D12.776.543.585.400.750.450.500
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| Concept/Terms |
G Protein-Coupled Inwardly-Rectifying Potassium Channels- G Protein-Coupled Inwardly-Rectifying Potassium Channels
- G Protein Coupled Inwardly Rectifying Potassium Channels
- GIRK Potassium Channels
- Potassium Channels, GIRK
- G Protein-Activated Potassium Channels
- G Protein Activated Potassium Channels
- Kir3 Potassium Channels
- Potassium Channels, Kir3
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Below are MeSH descriptors whose meaning is more general than "G Protein-Coupled Inwardly-Rectifying Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "G Protein-Coupled Inwardly-Rectifying Potassium Channels".
This graph shows the total number of publications written about "G Protein-Coupled Inwardly-Rectifying Potassium Channels" by people in this website by year, and whether "G Protein-Coupled Inwardly-Rectifying Potassium Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2009 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "G Protein-Coupled Inwardly-Rectifying Potassium Channels" by people in Profiles.
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Mamaligas AA, Cai Y, Ford CP. Nicotinic and opioid receptor regulation of striatal dopamine D2-receptor mediated transmission. Sci Rep. 2016 11 25; 6:37834.
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Monticone S, Hattangady NG, Nishimoto K, Mantero F, Rubin B, Cicala MV, Pezzani R, Auchus RJ, Ghayee HK, Shibata H, Kurihara I, Williams TA, Giri JG, Bollag RJ, Edwards MA, Isales CM, Rainey WE. Effect of KCNJ5 mutations on gene expression in aldosterone-producing adenomas and adrenocortical cells. J Clin Endocrinol Metab. 2012 Aug; 97(8):E1567-72.
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Liu C, Morishima M, Yu T, Matsui S, Zhang L, Fu D, Pao A, Costa AC, Gardiner KJ, Cowell JK, Nowak NJ, Nowak NJ, Parmacek MS, Liang P, Baldini A, Yu YE. Genetic analysis of Down syndrome-associated heart defects in mice. Hum Genet. 2011 Nov; 130(5):623-32.
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Ford CP, Phillips PE, Williams JT. The time course of dopamine transmission in the ventral tegmental area. J Neurosci. 2009 Oct 21; 29(42):13344-52.
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Aryal P, Dvir H, Choe S, Slesinger PA. A discrete alcohol pocket involved in GIRK channel activation. Nat Neurosci. 2009 Aug; 12(8):988-95.
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Beckstead MJ, Gantz SC, Ford CP, Stenzel-Poore MP, Phillips PE, Mark GP, Williams JT. CRF enhancement of GIRK channel-mediated transmission in dopamine neurons. Neuropsychopharmacology. 2009 Jul; 34(8):1926-35.
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Torrecilla M, Quillinan N, Williams JT, Wickman K. Pre- and postsynaptic regulation of locus coeruleus neurons after chronic morphine treatment: a study of GIRK-knockout mice. Eur J Neurosci. 2008 Aug; 28(3):618-24.
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Fowler CE, Aryal P, Suen KF, Slesinger PA. Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins. J Physiol. 2007 Apr 01; 580(Pt 1):51-65.
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Matthews DB, Bhave SV, Belknap JK, Brittingham C, Chesler EJ, Hitzemann RJ, Hoffmann PL, Lu L, McWeeney S, Miles MF, Tabakoff B, Williams RW. Complex genetics of interactions of alcohol and CNS function and behavior. Alcohol Clin Exp Res. 2005 Sep; 29(9):1706-19.
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Morishige KI, Inanobe A, Takahashi N, Yoshimoto Y, Kurachi H, Miyake A, Tokunaga Y, Maeda T, Kurachi Y. G protein-gated K+ channel (GIRK1) protein is expressed presynaptically in the paraventricular nucleus of the hypothalamus. Biochem Biophys Res Commun. 1996 Mar 18; 220(2):300-5.
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