 Methylphenidate
"Methylphenidate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
| Descriptor ID |
D008774
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| MeSH Number(s) |
D02.241.223.601.600 D03.383.621.460
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Methylphenidate".
Below are MeSH descriptors whose meaning is more specific than "Methylphenidate".
This graph shows the total number of publications written about "Methylphenidate" by people in this website by year, and whether "Methylphenidate" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 | | 2000 | 1 | 0 | 1 | | 2003 | 0 | 3 | 3 | | 2004 | 1 | 0 | 1 | | 2007 | 1 | 1 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 2 | 3 | | 2011 | 3 | 1 | 4 | | 2012 | 3 | 1 | 4 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 1 | 2 | | 2021 | 1 | 0 | 1 | | 2022 | 2 | 0 | 2 | | 2025 | 1 | 1 | 2 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Methylphenidate" by people in Profiles.
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Biernacki K, Zhai T, Hill J, McConnell E, Salmeron BJ, Kaiser RH, Janes AC. From rest to focus: pharmacological modulation of the relationship between resting state dorsal attention network dynamics and task-based brain activation. Neuropsychopharmacology. 2026 Apr; 51(5):926-933.
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Arciniegas DB, Seel RT, Macciocchi SN, Cifu DX, Frazier YG, Kaelin DL, Katz DI, Oyesanya TO, Wagner AK. Practice Guideline for Methylphenidate Use in Persons With Traumatic Brain Injury: Report of the American Congress of Rehabilitation Medicine. Arch Phys Med Rehabil. 2026 Apr; 107(4):753-760.
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Seel RT, Arciniegas DB, Macciocchi SP, Cifu DX, Frazier YG, Kaelin DL, Katz DI, Oyesanya TO, Pourrahmat M, Schofield T, Wagner AK, Fazeli MS. Systematic Review on Norepinephrine and Dopamine Reuptake Inhibitors for Traumatic Brain Injury-Related Symptoms: Report of the American Congress of Rehabilitation Medicine. Arch Phys Med Rehabil. 2026 Apr; 107(4):761-777.
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Singh A, Balasundaram MK. Comment on: "A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Efficacy and Safety of Viloxazine Extended-Release Capsules in Adults with Attention Deficit/Hyperactivity Disorder". CNS Drugs. 2022 12; 36(12):1331-1332.
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Kern D, Korsmo M, Baumgartner AJ, Kramer D, Ojemann S, Case M, Holt-Becker AB, Raike R, Thompson JA. Methylphenidate effects on a clinically informative oscillatory signal within the subthalamic nucleus in Parkinson's disease during deep brain stimulation programming. Brain Stimul. 2022 May-Jun; 15(3):747-749.
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Morris SSJ, Musser ED, Tenenbaum RB, Ward AR, Raiker JS, Coles EK. Methylphenidate Improves Autonomic Functioning among Youth with Attention-Deficit/Hyperactivity Disorder. Res Child Adolesc Psychopathol. 2022 05; 50(5):591-603.
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Harstad E, Shults J, Barbaresi W, Bax A, Cacia J, Deavenport-Saman A, Friedman S, LaRosa A, Loe IM, Mittal S, Tulio S, Vanderbilt D, Blum NJ. a2-Adrenergic Agonists or Stimulants for Preschool-Age Children With Attention-Deficit/Hyperactivity Disorder. JAMA. 2021 05 25; 325(20):2067-2075.
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Horne VE, Bielamowicz K, Nguyen J, Hilsenbeck S, Lindsay H, Sonabend R, Wood AC, Okcu F, Sisley S. Methylphenidate improves weight control in childhood brain tumor survivors with hypothalamic obesity. Pediatr Blood Cancer. 2020 07; 67(7):e28379.
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Mereu M, Hiranita T, Jordan CJ, Chun LE, Lopez JP, Coggiano MA, Quarterman JC, Bi GH, Keighron JD, Xi ZX, Newman AH, Katz JL, Tanda G. Modafinil potentiates cocaine self-administration by a dopamine-independent mechanism: possible involvement of gap junctions. Neuropsychopharmacology. 2020 08; 45(9):1518-1526.
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Childress A, Hoo-Cardiel A, Lang P. Evaluation of the current data on guanfacine extended release for the treatment of ADHD in children and adolescents. Expert Opin Pharmacother. 2020 Mar; 21(4):417-426.
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